Data/hora: 13/06/2024 01:15:28

Provedor de dados: | 17
País: | United Kingdom
Título: | 2011 German Escherichia coli outbreak: Alignment-free whole-genome phylogeny by feature frequency profiles
Autores: | Man Kit Cheung; Lei LI; Wenyan Nong; Hoi Shan Kwan.
Data: | 2011-07-12
Ano: | 2011
Palavras-chave: | Genetics &amp; Genomics; Microbiology; Bioinformatics; Evolutionary Biology.
Resumo: | Accuracy of SNP-based whole-genome phylogeny reconstruction relies heavily on quality of sequence alignment which is particularly hindered by poorly assembled genomes. Alignment-free methods might provide additional insights. Here, we constructed a whole-genome phylogeny of 9 E.coli isolates from the 2011 German outbreak against existing E. coli genomes using the alignment-free feature frequency profile method. In addition, we looked for gene elements that distinguish the outbreak group from the other E. coli strains and possibly accounted for the emergence of the outbreak isolates using the distinguishing feature analysis.
Tipo: | Manuscript

Identificador:

http://precedings.nature.com/documents/6109/version/1

oai:nature.com:10.1038/npre.2011.6109.1

http://dx.doi.org/10.1038/npre.2011.6109.1

Fonte: | Nature Precedings
Fonte: | Creative Commons Attribution 3.0 License