Data/hora: 10/06/2024 11:16:28

Provedor de dados: 	17	
País: 	United Kingdom	
Título: 	2011 German Escherichia coli O104:H4 outbreak: Alignment-free whole-genome phylogeny by feature frequency profiles	
Autores: 	Man Kit Cheung; Lei Li; Wenyan Nong; Hoi Shan Kwan.	
Data: 	2011-07-27	
Ano: 	2011	
Palavras-chave: 	Genetics &amp; Genomics; Microbiology; Bioinformatics; Evolutionary Biology.	
Resumo: 	Accuracy of SNP-based whole-genome phylogeny reconstruction relies heavily on quality of sequence alignment which is particularly hindered by poorly assembled genomes. Alignment-free methods might provide additional insights. Here, we constructed a whole-genome phylogeny of 10 isolates from the current German E. coli outbreak against 30 existing E. coli genomes as well as that of a historical EHEC isolate using the alignment-free feature frequency profile method. Our results revealed a high similarity among E. coli isolates from the current outbreak and the historical EHEC being the most closely related isolate sequenced thus far.	
Tipo: 	Manuscript	
Identificador: 	http://precedings.nature.com/documents/6109/version/2

oai:nature.com:10.1038/npre.2011.6109.2

http://dx.doi.org/10.1038/npre.2011.6109.2	
Fonte: 	Nature Precedings	
Fonte: 	Creative Commons Attribution 3.0 License