Data/hora: 04/06/2024 03:49:45

Provedor de dados: | 21
País: | Germany
Título: | Accuracy of direct genomic values for functional traits in Brown Swiss cattle
Autores: | Kramer, M.; Erbe, M.; Seefried, F.R.; Gredler, B.; Bapst, B.; Bieber, A.; Simianer, H.
Data: | 2014
Ano: | 2014
Palavras-chave: | Beef cattle; Breeding and genetics.
Resumo: | In this study, direct genomic values for the functional traits general temperament, milking temperament, aggressiveness, rank order in herd, milking speed, udder depth, position of labia, and days to first heat in Brown Swiss dairy cattle were estimated based on ∼777,000 (777k) single nucleotide polymorphism (SNP) information from 1,126 animals. Accuracy of direct genomic values was assessed by a 5-fold cross-validation with 10 replicates. Correlations between deregressed proofs and direct genomic values were 0.63 for general temperament, 0.73 for milking temperament, 0.69 for aggressiveness, 0.65 for rank order in herd, 0.69 for milking speed, 0.71 for udder depth, 0.66 for position of labia, and 0.74 for days to first heat. Using the information of ∼54,000 (54k) SNP led to only marginal deviations in the observed accuracy. Trying to predict the 20% youngest bulls led to correlations of 0.55, 0.77, 0.73, 0.55, 0.64, 0.59, 0.67, and 0.77, respectively, for the traits listed above. Using a novel method to estimate the accuracy of a direct genomic value (defined as correlation between direct genomic value and true breeding value and accounting for the correlation between direct genomic values and conventional breeding values) revealed accuracies of 0.37, 0.20, 0.19, 0.27, 0.48, 0.45, 0.36, and 0.12, respectively, for the traits listed above. These values are much smaller but probably also more realistic than accuracies based on correlations, given the heritabilities and samples sizes in this study. Annotation of the largest estimated SNP effects revealed 2 candidate genes affecting the traits general temperament and days to first heat.
Tipo: | Journal paper
Idioma: | Inglês

Identificador:

http://orgprints.org/25080/1/Kramer_2014_Accuracy%20of%20direct%20genomic%20values.pdf

Kramer, M.; Erbe, M.; Seefried, F.R.; Gredler, B.; Bapst, B.; Bieber, A. and Simianer, H.   (2014) Accuracy of direct genomic values for functional traits in Brown Swiss cattle.   Journal of Dairy Science, 97 (3), pp. 1774-1781.

urn:ISSN:1525-3198

info:doi/doi.org/10.3168/jds.2013-7054

Relação:

http://orgprints.org/25080/

doi.org/10.3168/jds.2013-7054

info:eu-repo/grantAgreement/EC/FP7/2226232

Formato: | application/pdf
Fonte: | info:eu-repo/semantics/restrictedAccess