Data/hora: 13/06/2024 05:44:57

Provedor de dados: | 52
País: | Brazil
Título: | Healing effect of the ointment made of Equisetum pyramidale in the treatment of cutaneous lesions in diabetic rats
Autores: | Corrêa,Andréia Cristina Lopes; Hans Filho,Guinter; Dourado,Doroty Mesquita; Matias,Rosemary; Silva,Iandara Schettert da; Sarragiotto,Maria Helena.
Data: | 2013-06-01
Ano: | 2013
Palavras-chave: | Diabetes; Skin lesions; Medicinal plants; Anti-inflammatory activity; Reepithelialization tissue.
Resumo: | This study aimed to evaluate the anti-inflammatory and repair effects of the ethanolic extract and ointment of Equisetum pyramidale on the skin lesions of rats induced to diabetes. After the induction of diabetes with alloxan, a surgical procedure was performed on the back of each rat. Then, they were separated into treatment groups: G1 ethanol extract of E. pyramidale; G2-ointment (extract of E. pyramidale 80g + 20g of vaseline:lanolin 1:1); G3 control (vehicle vaseline:lanolin 1:1); and G4-no treatment during 3, 7 and 14 days. The samples were embedded in paraffin and stained with hematoxylin-eosin for histological analysis. The findings showed that the use of ethanolic extract as well as the ointment decreased the inflammatory cells at the site of inflammation, resulting a faster healing, with less crusting and lower amount of secretion in comparison to the control group. Therapy with topical herbal was an effective method in the inflammatory process of tissue repair, contributing to a faster and more organized tissue re-epithelialization.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000300005
Editor: | Instituto de Tecnologia do Paraná - Tecpar
Relação: | 10.1590/S1516-89132013000300005
Formato: | text/html
Fonte: | Brazilian Archives of Biology and Technology  v.56 n.3 2013
Fonte: | info:eu-repo/semantics/openAccess