Data/hora: 03/06/2024 01:22:09

Provedor de dados: | 52
País: | Brazil
Título: | Efeito do etanol e do peróxido de hidrogênio intragástrico sobre a mucosa gástrica de rã (Rana catesbeiana, SHAW)
Autores: | Estivallet,Hidê Virgínia; Rodrigues,Maria Inês; Marroni,Norma Possa.
Data: | 1998-06-01
Ano: | 1998
Palavras-chave: | Gastric acid secretion; Mucus; Ethanol; Hydrogen peroxide; Frog.
Resumo: | This work investigated the frog gastric mucosa response to hydrogen peroxide and ethanol induced injury. Acid and mucus secretion were estimated "in vitro" in control animals with intragastric absolute ethanol (1ml/30min. or 2ml/60min.) and hydrogen peroxide. The gastric mucosa morphological conditions were assessed "in vivo", concerning lesion area, pH and mucus. Ethanol (1ml/30min.) was observed to cause hyperemia, cell damage, rupture, edema, erosions, necrosis in gastric mucosa and significant increase in acid secretion. Absolute ethanol (2ml/60min.) caused a decrease in acid secretion due to alcalinization and an increase of mucus and pH. Intragastric hydrogem peroxide provoked gastric unwrinkling and hyperemia, acid secretions were not increased, mucus fragmented and the pH was decreased. The results indicate an increase of mucus and acid in response to ethanol and unwrinkling and hyperemia to hydrogen peroxide.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Português
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89131998000100007
Editor: | Instituto de Tecnologia do Paraná - Tecpar
Relação: | 10.1590/S1516-89131998000100007
Formato: | text/html
Fonte: | Brazilian Archives of Biology and Technology  v.41 n.1 1998
Fonte: | info:eu-repo/semantics/openAccess