Data/hora: 10/06/2024 09:00:34

Provedor de dados: 	55	
País: 	Brazil	
Título: 	Chronic skull osteomyelitis due to Cryptococcus neoformans: first case report in an HIV-infected patient	
Autores: 	Adiwardana,Natanael Sutikno; Morás,Juliana de Angelo; Bernardo,Leandro Lombo; Klautau,Giselle Burlamaqui; Queiroz,Wladimir; Vidal,Jose Ernesto.	
Data: 	2018-11-01	
Ano: 	2018	
Palavras-chave: 	Cryptococcus neoformans; Osteomyelitis; Skull; HIV.	
Resumo: 	ABSTRACT Osteomyelitis due to Cryptococcus neoformans are described in mostly 10% of patients with disseminated cryptococcosis, being direct inoculation even more uncommon. We report the case of an HIV-infected patient with history of recurring itching on his scalp and repetitive local trauma. For eighteen months, he noticed a painful and slow growing lump on his scalp. He was submitted to an excisional biopsy of the lesion but no etiological diagnosis was identified. After this procedure, the post-surgical wound never completely healed. At admission, the patient presented nausea and headache for three days and an open orifice into his skull. Investigations confirmed meningitis and skull osteomyelitis caused by Cryptococcus neoformans. He was treated with bone debridement and combined systemic antifungals, showing good clinical and laboratorial outcome. Cryptococcal disease should be included in the differential diagnoses of chronic osteomyelitis in HIV-infected patients and trauma is a possible source of infection.	
Tipo: 	Info:eu-repo/semantics/report	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000600499	
Editor: 	Brazilian Society of Infectious Diseases	
Relação: 	10.1016/j.bjid.2018.11.004	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Infectious Diseases  v.22 n.6 2018	
Fonte: 	info:eu-repo/semantics/openAccess