Data/hora: 11/06/2024 14:39:01

Provedor de dados: | 56
País: | Brazil
Título: | Two novel Mg(II)-based and Zn(II)-based complexes: inhibiting growth of human liver cancer cells
Autores: | Liu,N.; Ding,D.; Wang,L.; Zhao,H.; Zhu,L.; Geng,X.
Data: | 2018-01-01
Ano: | 2018
Palavras-chave: | Coordination polymer; Pillar-layered; Liver cancer.
Resumo: | Two new Mg(II)-based and Zn(II)-based coordination polymers, {[Mg3(BTB)(DMA)4](DMA)2}n (1, H3BTB=1,3,5-benzenetrisbenzoic acid, DMA=N,N-dimethylacetamide) and {(H2NMe2)2[Zn3(BTB)2(OH)(Im)](DMF)9(MeOH)7}n (2, Im=imidazole, DMF=N,N-dimethylformamide), have been successfully synthesized and structurally characterized under solvothermal conditions. 1 contains a linear [Mg3(COO)6] cluster that connected by the fully deprotonated BTB3- ligands to give a kgd-type 2D bilayer structure; 2 represents a microporous 3D pillar-layered system based on the binuclear Zn units and pillared Im ligands, which shows a (3,5)-connected hms topological net. In addition, in vitro anticancer activities of compounds 1 and 2 on 4 human liver cancer cells (HB611, HHCC, BEL-7405 and SMMC-7721) were determined.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000200614
Editor: | Associação Brasileira de Divulgação Científica
Relação: | 10.1590/1414-431x20176929
Formato: | text/html
Fonte: | Brazilian Journal of Medical and Biological Research  v.51 n.2 2018
Fonte: | info:eu-repo/semantics/openAccess