Data/hora: 02/06/2024 13:09:01

Provedor de dados: | 58
País: | Brazil
Título: | Anti-foot-and-mouth disease virus effects of Chinese herbal kombucha in vivo
Autores: | Fu,Naifang; Wu,Juncai; Lv,Lv; He,Jijun; Jiang,Shengjun.
Data: | 2015-12-01
Ano: | 2015
Palavras-chave: | FMD; FMDV; Chinese herbal kombucha.
Resumo: | Abstract The foot and mouth disease virus (FMDV) is sensitive to acids and can be inactivated by exposure to low pH conditions. Spraying animals at risk of infection with suspensions of acid-forming microorganisms has been identified as a potential strategy for preventing FMD. Kombucha is one of the most strongly acid-forming symbiotic probiotics and could thus be an effective agent with which to implement this strategy. Moreover, certain Chinese herbal extracts are known to have broad-spectrum antiviral effects. Chinese herbal kombucha can be prepared by fermenting Chinese herbal extracts with a kombucha culture. Previous studies demonstrated that Chinese herbal kombucha prepared in this way efficiently inhibits FMDV replication in vitro. To assess the inhibitory effects of Chinese herbal kombucha against FMDV in vitro, swine challenged by intramuscular injection with 1000 SID50 of swine FMDV serotype O strain O/China/99 after treatment with Chinese herbal kombucha were partially protected against infection, as demonstrated by a lack of clinical symptoms and qRT-PCR analysis. In a large scale field trial, spraying cattle in an FMD outbreak zone with kombucha protected against infection. Chinese herbal kombucha may be a useful probiotic agent for managing FMD outbreaks.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000401245
Editor: | Sociedade Brasileira de Microbiologia
Relação: | 10.1590/S1517-838246420140701
Formato: | text/html
Fonte: | Brazilian Journal of Microbiology  v.46 n.4 2015
Fonte: | info:eu-repo/semantics/openAccess