Data/hora: 03/06/2024 02:50:54

Provedor de dados: | 65
País: | Brazil
Título: | Hematological, biochemical, and blood gas alterations of goat whole blood stored in CPDA-1 and CPD/SAG-M plastic bags
Autores: | Tavares,Marcondes Dias; Barros,Isabella de Oliveira; Sousa,Rejane dos Santos; Firmino,Paulo Ricardo; Gameleira,Jucelio da Silva; Oliveira,Francisco Leonardo Costa de; Minervino,Antonio Humberto Hamad; Ortolani,Enrico Lippi; Alves Barrêto-Júnior,Raimundo.
Data: | 2019-01-01
Ano: | 2019
Palavras-chave: | Transfusion; Red blood cell; Hemolysis; Blood therapy; Goats.
Resumo: | ABSTRACT:  The aim of this study was to evaluate the hematological, biochemical, and blood gas alterations of goat whole blood stored in different blood bags. Seven male, adult, crossbreed goats were used, weighing 62±1.8 kg. Nine hundred milliliters of whole blood from each animal was collected and stored in blood bags (450 ml in each), CPDA-1 (citrate phosphate dextrose-adenine) and CPD/SAG-M (citrate phosphate dextrose with saline-glucose-mannitol) as additive solutions, and kept refrigerated (2-4 ºC) for 42 days. Blood samples were collected from the plastic bags at baseline (T0) and after seven, 14, 21,28, 35, and 42 days for hematological, biochemical, blood gas, and microbiological evaluations. Free hemoglobin, degree of hemolysis, lactate, and pO2were increased in both bags, whereas hydrogen potential (pH) and the total hemoglobin concentration decreased overtime(P&lt;0.05). The red blood cell count, glucose, sodium, and potassium remained stable, compared to the baseline. The CPD/SAG-M bag presented a lower red cell count, globular volume, total hemoglobin, and sodium, and a higher degree of hemolysis and plasma hemoglobin, compared with the CPDA-1 bag. The whole goat blood remained viable for therapeutic use; although, there were some important changes in the variables of the 42-day stored blood in relation to fresh blood (T0). We concluded that the CPDA-1 bag is more suitable for use in the storage of goat blood because of its lower commercial value.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019001000604
Editor: | Universidade Federal de Santa Maria
Relação: | 10.1590/0103-8478cr20190267
Formato: | text/html
Fonte: | Ciência Rural  v.49 n.10 2019
Fonte: | info:eu-repo/semantics/openAccess