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Provedor de dados: |
Biocell
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País: |
Argentina
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Título: |
Effects of the ascorbic acid supplementation on NADH-diaphorase myenteric neurons in the duodenum of diabetic rats
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Autores: |
Pereira,Marli Aparecida Dos Santos
Bagatin,Maria Claúdia
Zanoni,Jacqueline Nelisis
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Data: |
2006-08-01
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Ano: |
2006
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Palavras-chave: |
Diabetes mellitus
Ascorbic acid
Myenteric neurons
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Resumo: |
We assessed the ascorbic acid (AA) supplementation on the myenteric neurons in the duodenum of rats. Fifteen rats with 90 days of age were divided into three groups: control (C), diabetics (D) and ascorbic acid treated diabetics (DA). After 120 days of daily treatment with AA, the duodenum was submitted to the NADH-diaphorase (NADH-d) histochemical technique, which allowed us to evaluate the neuronal density in an area of 8.96 mm² for each duodenum, and also to measure the cellular profile area of 500 neurons per group. The supplementation promoted an increase on AA levels. The neuronal density (p <0.05) was higher in the group DA when compared to group D. There were no significant differences in the neuronal areas, when we compared groups C (204 ± 16.5) and D (146.3 ± 35.84) to groups D and DA (184.5 ± 5.6) (p>0.05). The AA-supplementation avoided the density reduction of the NADHd myenteric neurons in the duodenum of diabetic rats.
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Tipo: |
Info:eu-repo/semantics/article
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Idioma: |
Inglês
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Identificador: |
http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452006000200005
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Editor: |
Sociedad Latinoamericana de Microscopía Electrónica.; Centro Regional de Investigaciones Científicas y Tecnológicas (Mendoza, Argentina)
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Formato: |
text/html
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Fonte: |
Biocell v.30 n.2 2006
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Direitos: |
info:eu-repo/semantics/openAccess
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