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Provedor de dados:  BABT
País:  Brazil
Título:  Alveolus-capillary permeability on both normal and HIV seroreactive individuals
Autores:  Carriel,José Carlos
Maliska,Carmelindo
Piloto,José Henrique
Norberg,Antônio Neres
D’Almeida,Joaquim
Ferreira,Gilsy S.
Penas,Maria Expósito
Data:  2007-11-01
Ano:  2007
Palavras-chave:  HIV seroreactive
Alveolus-capillary permeability
99mTc-DTPA clearance
Pneumocystis pneumonia
Resumo:  The aim of this study was to evaluate the alveolus-capillary permeability by the lung clearance rate of 99mTc-DTPA(Technetium99m-diethylene triamine penta-acetate), (LCR-DTPA), both in normal and in asymptomatic HIV seroreactive patients. Thirty individuals were studied, 21 seronegative normal volunteers and 9 HIV seroreactive patients presenting normal chest radiography and no respiratory infection symptoms. LCR-DTPA was determined by inhaling 99mTc-DTPA and obtaining images in a gamma camera. The 99mTc-DTPA clearance rate in normal individuals was 0.99±0.15%.min-1 and in patients 2.31±1.25%.min-1. There was a significant statistical difference between the two groups (p< 0.05). Two patients who presented LCR-DTPA higher than 4.3 %.min-1 presented pneumocystis pneumonia one month later. Seroreactive AIDS patients, previously asymptomatic that presented pneumonia later showed higher LCR-DTPA than the seroreactive who did not develop the illness. These results suggested that LCR-DTPA could be a predictive method for the clinical development of pneumocystis pneumonia in asymptomatic HIV seroreactive patients.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000700008
Editor:  Instituto de Tecnologia do Paraná - Tecpar
Relação:  10.1590/S1516-89132007000700008
Formato:  text/html
Fonte:  Brazilian Archives of Biology and Technology v.50 n.6 2007
Direitos:  info:eu-repo/semantics/openAccess
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