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Provedor de dados: |
BABT
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País: |
Brazil
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Título: |
Alveolus-capillary permeability on both normal and HIV seroreactive individuals
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Autores: |
Carriel,José Carlos
Maliska,Carmelindo
Piloto,José Henrique
Norberg,Antônio Neres
DAlmeida,Joaquim
Ferreira,Gilsy S.
Penas,Maria Expósito
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Data: |
2007-11-01
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Ano: |
2007
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Palavras-chave: |
HIV seroreactive
Alveolus-capillary permeability
99mTc-DTPA clearance
Pneumocystis pneumonia
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Resumo: |
The aim of this study was to evaluate the alveolus-capillary permeability by the lung clearance rate of 99mTc-DTPA(Technetium99m-diethylene triamine penta-acetate), (LCR-DTPA), both in normal and in asymptomatic HIV seroreactive patients. Thirty individuals were studied, 21 seronegative normal volunteers and 9 HIV seroreactive patients presenting normal chest radiography and no respiratory infection symptoms. LCR-DTPA was determined by inhaling 99mTc-DTPA and obtaining images in a gamma camera. The 99mTc-DTPA clearance rate in normal individuals was 0.99±0.15%.min-1 and in patients 2.31±1.25%.min-1. There was a significant statistical difference between the two groups (p< 0.05). Two patients who presented LCR-DTPA higher than 4.3 %.min-1 presented pneumocystis pneumonia one month later. Seroreactive AIDS patients, previously asymptomatic that presented pneumonia later showed higher LCR-DTPA than the seroreactive who did not develop the illness. These results suggested that LCR-DTPA could be a predictive method for the clinical development of pneumocystis pneumonia in asymptomatic HIV seroreactive patients.
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Tipo: |
Info:eu-repo/semantics/article
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Idioma: |
Inglês
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Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000700008
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Editor: |
Instituto de Tecnologia do Paraná - Tecpar
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Relação: |
10.1590/S1516-89132007000700008
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Formato: |
text/html
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Fonte: |
Brazilian Archives of Biology and Technology v.50 n.6 2007
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Direitos: |
info:eu-repo/semantics/openAccess
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