| Registro completo |
| Provedor de dados: |
PAB
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| País: |
Brazil
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| Título: |
Genetic characterization of coat color genes in Brazilian Crioula sheep from a conservation nucleus
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| Autores: |
Cavalcanti,Lilian Cristina Gomes
Moraes,José Carlos Ferrugem
Faria,Danielle Assis de
McManus,Concepta Margaret
Nepomuceno,Alcebiades Renato
Souza,Carlos José Hoff de
Caetano,Alexandre Rodrigues
Paiva,Samuel Rezende
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| Data: |
2017-08-01
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| Ano: |
2017
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| Palavras-chave: |
Ovis aris
ASIP
Genetic resources conservation
Marker-assisted selection
MC1R
TYRP1
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| Resumo: |
Abstract: The objective of this work was to identify single nucleotide polymorphisms (SNPs) in resequencing data from MC1R, ASIP, and TYRP1 genes derived from Crioula sheep (Ovis aris) with different coat colors. Polymorphisms in the ASIP (agouti-signaling protein), MC1R (melanocortin 1 receptor), and TRYP1 (tyrosinase-related protein 1) genes were analyzed in 115 sheep from Embrapa’s conservation nucleus of crioula sheep, in Brazil. A total of 7,914 bp were sequenced per animal, and 14 SNPs were identified. Two additional assays were performed to detect duplications and deletions in the ASIP gene. Ninety-five percent of the coat color variation was explained by epistatic interactions observed between specific alleles in the MC1R and ASIP genes. Evidence suggests an important role of TYRP1 variants for wool color, despite their low frequencies. The marker panel was efficient enough in predicting coat color in the studied animals and, therefore, can be used to implement a marker-assisted selection program in the conservation nucleus of sheep of the crioula breed.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2017000800615
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| Editor: |
Embrapa Secretaria de Pesquisa e Desenvolvimento
Pesquisa Agropecuária Brasileira
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| Relação: |
10.1590/s0100-204x2017000800007
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| Formato: |
text/html
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| Fonte: |
Pesquisa Agropecuária Brasileira v.52 n.8 2017
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| Direitos: |
info:eu-repo/semantics/openAccess
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