Consulta: creatorFacets:"Adjafre, Beatriz Lima"
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Data/hora: 13/06/2024 04:09:00

Venom of the giant ant Dinoponera quadriceps attenuates inflammatory pain in mouse cutaneous wound healing model
Provedor de dados: 3
Autores: Assreuy, Ana Maria Sampaio; Adjafre, Beatriz Lima; Sousa, Évilla Rayanne Oliveira; Alves, Ana Paula Negreiros Nunes; Pires, Alana de Freitas; Quinet, Yves; Mota, Mário Rogério Lima.
Arthropod venoms are potential sources of bioactive substances, providing tools for the validation of popular use and new drugs design. Ants belonging to the genus Dinoponera are used in the folk medicine to treat inflammatory conditions. It was previously demonstrated that the venom of the giant ant Dinoponera quadriceps (DqV), containing a mixture of polypeptides, elicit antinociceptive effect in mice models of chemical, mechanical and thermal nociception. The aim of this study was to evaluate DqV antiinflammatory and antihypernociceptive effects in a mice model of traumatic cutaneous wound. Colonies of D. quadriceps were collected in the ‘‘Serra de Maranguape’’ (State of Ceará, northeastern Brazil), a small mountain range located on the coastal zone,...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: DqV; Hypernociception; Leukocyte infiltrate; Scar.
Ano: 2020
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/47680