Consulta: subjectFacets:"Efficacy"
Registros recuperados: 14
Data/hora: 11/06/2024 10:03:34

Risks of vaccination: a review
Provedor de dados: 80
Autores: Rashid,A; Rasheed,K; Asim,M; Hussain,A.
To be granted a product license, a vaccine must present adequate quality, safety and efficacy. Studies on these criteria often utilize target species in a laboratory setting. Vaccines that had been proven effective during laboratory analysis may not present the same features when sold on a large scale, after encountering field conditions, and furthermore, can even produce complications. Measures are already in place to detect adverse reactions as reported by veterinarians to manufacturers, so that vaccines under suspicion of failing can be identified and investigated. The present review article describes the main problems, specifically adverse reactions and lack of efficacy, that have been encountered following release of vaccines for general use.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Vaccine; Quality; Safety; Efficacy; Adverse reactions.
Ano: 2009
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000100003

A bioassay method for black flies (Diptera: Simuliidae) using larvicides
Provedor de dados: 82
Autores: Araújo-Coutinho,Carlos J.P.C.; Figueiró,Ronaldo; Viviani,Andréia P.; Nascimento,Érika S.; Cavados,Clara F.G.
This note presents an alternative method for bioassays using black fly larvae, with which we intend to provide a simpler but effective tool for accessing data on larvicide efficacy.
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Biological control; Efficacy; Technique.
Ano: 2005
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-566X2005000300022

ANNUAL GRASSES CONTROL WITH TOPRAMEZONE IN MIXTURE WITH ALS-INHIBITING HERBICIDES
Provedor de dados: 87
Autores: DAMALAS,C. A.; GITSOPOULOS,T. K.; KOUTROUBAS,S.D.; GEORGOULAS,I.
ABSTRACTPanicoid grasses are major weeds of maize and sugarcane as well as of several other important grains, including sorghum, pearl millet, and foxtail millet. Pot trials were conducted to study the activity and potential interactions of topramezone in mixture with recommended rates of rimsulfuron or nicosulfuron on three annual panicoid grasses (i.e. Echinochloa oryzoides,E.phyllopogon, and Panicum miliaceum). Target weeds were treated at the four- to five-leaf growth stage. On the basis of fresh weight reduction, topramezone alone provided 78% control of E.oryzoides, 68% control of E.phyllopogon, and 99% control of P.miliaceum. Topramezone plus rimsulfuron or nicosulfuron provided decreased control of both Echinochloa spp. compared with topramezone...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Efficacy; Nicosulfuron; Mixtures; Rimsulfuron.
Ano: 2015
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582015000300509

Self efficacy as a mediator of the relationship between dietary knowledge and behavior
Provedor de dados: 31
Autores: Rimal,   Arbindra; Moon,   Wanki.
This study examines the causal relationship between dietary knowledge and behavior by including self-efficacy in the models. Regression analyses supported the hypothesized relationships that self-efficacy mediates effects of dietary knowledge and social influences on dietary behavior. Self-efficacy also accounted for variance in eating behavior not explained by knowledge or demographic variables.  The coefficients for the relationship between dietary behavior and knowledge decreased for each of the four dietary models when the influence of self efficacy was added.  Interventions and health promotion campaigns should seek to directly address factors influencing diet related self-efficacy instead of focusing on disseminating information only.
Tipo: Conference Paper or Presentation
Palavras-chave: Efficacy; Mediation; Health Knowledge; Agricultural and Food Policy; Consumer/Household Economics; Health Economics and Policy.
Ano: 2009
URL: http://purl.umn.edu/46742

Eficácia e evolução dos indicadores socioeconômicos de famílias beneficiadas pelo programa de combate à pobreza rural /Projeto São José no Estado do Ceará
Provedor de dados: 31
Autores: Khan,   Ahmad Saeed; Silva,   Lucia Maria Ramos.
The objective of this study was to verify the evolution of economic indicators of the families, living in 27 communities, benefited by Rural Poverty Reduction Program in the state of Ceará. For this purpose, the years of 1998 (base year) and 2001 were selected. The information was obtained from the beneficiaries of projects such as water supply, rural electrification, agriculture mechanization and land reform. The results allowed to conclude that there was an improvement in living conditions, acquisition of durable goods and income level of population benefited by the Program. Also, comparison between per capita income of these families and rural population of the state was made.
Tipo: Journal Article
Palavras-chave: Efficacy; Welfare; Ceará; Agribusiness; Q12; Q28.
Ano: 2007
URL: http://purl.umn.edu/61927

A CHOICE-EXPERIMENT BASED ANALYSIS OF PROTECTION MOTIVATION THEORY: HEALTH RELATED BEHAVIOR OF CONSUMERS WITH CELIAC DISEASE
Provedor de dados: 31
Autores: Zhang,   Jing; Steiner,   Bodo E.
The underlying components of protection motivation theory (PMT; Rogers 1983) are explored through choice experiment-based analysis within a random utility framework, to account for some of the motivational, cognitive, and affective processes that likely affect celiacs’ propensity to use a novel health-risk reducing product. Those four groups of variables that are aimed to capture threat appraisal and coping appraisal processes as part of the standard PMT (Rogers 1975, 1983; Floyd et al. 2000) are found to contribute significantly to explaining the adaptive response of celiacs. Self-assessed vulnerability and perceived product efficacy form a most significant part of respondents’ threat appraisal process. Standard socio-demographic and lifestyle...
Tipo: Conference Paper or Presentation
Palavras-chave: Celiac disease; Protection motivation theory; Choice experiments; Confidence; Risk perceptions; Vulnerability; Efficacy; Agricultural and Food Policy; Consumer/Household Economics; Demand and Price Analysis; Food Consumption/Nutrition/Food Safety; Food Security and Poverty; Health Economics and Policy; D03; D12.
Ano: 2010
URL: http://purl.umn.edu/116454

Evaluation of proposed integrated diseases management strategies in blackberry cultivation according to its sustainability
Provedor de dados: 94
Autores: Narváez,Yimmy Alexander Zapata; Beltrán-Acosta,Camilo Rubén.
Abstract  The production of blackberry in Colombia is a source of income and rural employment in 18 departments; however, the plant is affected by diseases such as gray mold, anthracnose and powdery mildew that can cause losses of up to 70%. The control of these diseases is mainly carried out with chemical fungicides such as benomyl, carbendazim and mancozeb applied every 7 or 15 days. Nevertheless, being a continuous fructification plant of weekly harvest, the proximity between the application of the pesticides, the harvest, and its consumption represents a health risk due to the residually of these molecules, condition that affects its innocuousness and sustainability. Accordingly, this work aimed to develop an integrated management strategy for these...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Control; Efficacy; Food safety; Environmental impact; Residuality.
Ano: 2019
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-29452019000500406

Durability of the first combined antiretroviral regimen in patients with AIDS at a reference center in Belo Horizonte, Brazil, from 1996 to 2005
Provedor de dados: 55
Autores: Ribeiro,Flávia Andrade; Tupinambás,Unaí; Fonseca,Marise Oliveira; Greco,Dirceu Bartolomeu.
Finding a better first antiretroviral regimen is one of the strategies used to improve span and quality of life of HIV/AIDS patients. 891 patients were followed during 24 months or until interruption/abandonment of treatment, changing regimen or death. At the end of 6 months, 69% of the patients were still being treated with the first regimen, 54% at 12 months, 48% at 18 months and 39% at 24 months. AZT-3TC-EFV was the most prescribed regimen and with the lesser discontinuation. NNRTI regimens showed high effectiveness and durability compared to PI regimens. Irregular medication dispensation was the only risk factor for failure/interruption of treatment in multivariate analyses. Intolerance/adverse effects were mainly responsible for first regimen...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: HIV; AIDS; HAART; Durability; Efficacy.
Ano: 2012
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000100005

Peginterferon alfa-2a (40KD) (PEGASYS®) plus ribavirin (COPEGUS®) in retreatment of chronic hepatitis C patients, nonresponders and relapsers to previous conventional interferon plus ribavirin therapy
Provedor de dados: 55
Autores: Parise,E.; Cheinquer,H.; Crespo,D.; Meirelles,A.; Martinelli,A.; Sette,H.; Gallizi,J.; Silva,R.; Lacet,C.; Correa,E.; Cotrim,H.; Fonseca,J.; Paraná,R.; Spinelli,V.; Amorim,W.; Tatsch,F.; Pessoa,M.
Peginterferon alfa plus ribavirin is currently the treatment of choice for chronic hepatitis C. Peginterferon alfa-2a (40KD) plus ribavirin has given an overall sustained virological response of 18% in F3/F4 previous nonresponder US patients. We evaluated the effectiveness of peginterferon alfa-2a (40KD) plus ribavirin in Brazilian patients who were relapsers or nonresponders to previous interferon-based therapy. One-hundred-thirty-four patients with biopsy-proven chronic hepatitis C, HCV RNA positive, elevated ALT and who were either relapsers (n=37) or nonresponders (n=97) to at least 24 weeks of conventional interferon/ribavirin therapy were retreated with peginterferon alfa-2a (40KD) 180mg/qw and ribavirin 800mg bid for 48 weeks. Efficacy was assessed...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Peginterferon alfa; Ribavirin; Hepatitis C; Safety; Efficacy.
Ano: 2006
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000100003

Efficacy of a quadruple therapy regimen for Helicobacter pylori eradication after partial gastrectomy
Provedor de dados: 56
Autores: Zhang,F.; Bao,Z.J.; Shi,D.M.; Xiang,P.; Xiao,L.; Huang,Y.Q.; Zhang,G.S.; Yin,S.M.
We aimed to evaluate the effectiveness and safety of bismuth-containing quadruple therapy plus postural change after dosing for Helicobacter pylori eradication in gastrectomized patients. We compared 76 gastric stump patients with H. pylori infection (GS group) with 50 non-gastrectomized H. pylori-positive patients who met the treatment indication (controls). The GS group was divided into GS group 1 and GS group 2. All groups were administered bismuth potassium citrate (220 mg), esomeprazole (20 mg), amoxicillin (1.0 g), and furazolidone (100 mg) twice daily for 14 days. GS group 1 maintained a left lateral horizontal position for 30 min after dosing. H. pylori was detected using rapid urease testing and histologic examination of gastric mucosa before and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Helicobacter pylori; Gastrectomy; Gastric stump; Eradication; Efficacy.
Ano: 2016
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000200702

Psychopharmacotherapy of panic disorder: 8-week randomized trial with clonazepam and paroxetine
Provedor de dados: 56
Autores: Nardi,A.E.; Valença,A.M.; Freire,R.C.; Mochcovitch,M.D.; Amrein,R.; Sardinha,A.; Levitan,M.N.; Nascimento,I.; de-Melo-Neto,V.L.; King,A.L.; de O. e Silva,A.C.; Veras,A.B.; Dias,G.P.; Soares-Filho,G.L.; da Costa,R.T.; Mezzasalma,M.A.; de Carvalho,M.R.; de Cerqueira,A.C.; Hallak,J.E.; Crippa,J.A.; Versiani,M.
The objective of the present randomized, open-label, naturalistic 8-week study was to compare the efficacy and safety of treatment with clonazepam (N = 63) and paroxetine (N = 57) in patients with panic disorder with or without agoraphobia. Efficacy assessment included number of panic attacks and clinician ratings of the global severity of panic disorders with the clinical global impression (CGI) improvement (CGI-I) and CGI severity (CGI-S) scales. Most patients were females (69.8 and 68.4% in the clonazepam and paroxetine groups, respectively) and age (mean ± SD) was 35.9 ± 9.6 years for the clonazepam group and 33.7 ± 8.8 years for the paroxetine group. Treatment with clonazepam versus paroxetine resulted in fewer weekly panic attacks at week 4 (0.1 vs...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Paroxetine; Clonazepam; Panic disorder; Efficacy; Safety.
Ano: 2011
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000400015

Therapy of tacrolimus combined with corticosteroids in idiopathic membranous nephropathy
Provedor de dados: 56
Autores: Cui,W.; Lu,X.; Min,X.; Liu,M.; Guan,S.; Wang,Y.; Luo,M.; Li,W.; Li,Q.; Dong,W.; Miao,L.; Luo,P.
We evaluated the efficacy and safety of tacrolimus (TAC) combined with corticosteroids in treating patients with idiopathic membranous nephropathy (IMN). One hundred seventy-seven biopsy-proven IMN patients were recruited in this retrospective clinical study. Sixty patients received TAC (target blood concentration of 4–8 ng/mL) and 117 patients received daily cyclophosphamide (CYC, 100 mg) combined with prednisone. Remission rates at the end of the first, second and third month in the TAC group were significantly higher than that in the CYC group (1st: 35.0 vs 19.7%, P&lt;0.05; 2nd: 56.7 vs 38.5%, P&lt;0.05; 3rd: 76.7 vs 59.0%, P&lt;0.05). In the first 3 months, daily urinary protein and serum albumin in the TAC group obtained a better improvement than...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cyclophosphamide; Efficacy; Idiopathic membranous nephropathy; Retrospective clinical study; Tacrolimus.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000400703

Effects of vacuum sealing drainage on the treatment of cranial bone-exposed wounds in rabbits
Provedor de dados: 56
Autores: Chen,X.J.; Liu,S.; Gao,G.Z.; Yan,D.X.; Jiang,W.S.
This study was designed to assess the efficacy of vacuum sealing drainage (VSD) on skull exposure wounds in rabbits and to investigate the underlying mechanism of the process. Full-thickness excisional circular wounds 2×2 cm with or without periosteum involvement were created in 88 New Zealand white rabbits (mean body weight: 3.0±0.65 kg). Animals were randomly divided into 4 groups: periosteum-intact wounds treated with traditional dressing (p+control), periosteum-intact wounds treated with VSD (p+VSD), periosteum-lacking wounds treated with traditional dressing (p–control) and periosteum-lacking wounds treated with VSD (p–VSD). The wounds treated with traditional dressing were covered with Vaseline gauze, while VSD treatment was accompanied with...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Cranial bone-exposed wound; Vacuum sealing drainage; Periosteum; Wound healing; Efficacy.
Ano: 2017
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017001200602

Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents)
Provedor de dados: 56
Autores: Calixto,J.B.
This review highlights the current advances in knowledge about the safety, efficacy, quality control, marketing and regulatory aspects of botanical medicines. Phytotherapeutic agents are standardized herbal preparations consisting of complex mixtures of one or more plants which contain as active ingredients plant parts or plant material in the crude or processed state. A marked growth in the worldwide phytotherapeutic market has occurred over the last 15 years. For the European and USA markets alone, this will reach about $7 billion and $5 billion per annum, respectively, in 1999, and has thus attracted the interest of most large pharmaceutical companies. Insufficient data exist for most plants to guarantee their quality, efficacy and safety. The idea that...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Herbal medicine; Efficacy; Safety; Quality control; Market; Regulatory guidelines.
Ano: 2000
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000200004