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| Registros recuperados: 26 | |
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| MIYAHARA, Kazuro; YOKOO, Naoya; SAKURAI, Haruhisa; IGARASHI, Ikuo; SAKATA, Yu; YOSHIDA, Yutaka; SAITO, Atsushi; HIROSE, Tsuneo; SUZUKI, Naoyoshi; 宮原, 和郎; 五十嵐, 郁男. |
| Growth of the tumor autoinduced by 20-methylcholanthrene (MC) in rats was inhibited after administration of Toxoplasma lysate antigen (TLA). The antitumor activity of TLA was most obvious in the early stage of tumoral growth. When TLA was administered to rats before the appearance of tumor, tumor formation was delayed slightly. Histopathological studies revealed dense growths of spindle tumor cells in untreated control rat, while enlarged central necrosis with the infiltration of lymphocytes and neutrophils was apparent in TLA-treated rats. According to the immunohistological examination of tumor tissue with anti-Thy-1 antibody, the rats treated with TLA showed large Thy-1 positive granular cells, whereas the untreated rats indicated only a few small Thy-1... |
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Palavras-chave: Antitumor activity; Methylcholanthrene-autoinduced tumor; Rat; Thy-1 positive granular cell; Toxoplasma lysate antigen. |
| Ano: 1992 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4064 |
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| 青木, 大介; 滄木, 孝弘; 下田, 崇; 富樫, 義彦; 風間, 武彦; 吉林台; 宮原, 和郎; 古林, 与志安; 古岡, 秀文; 松井, 高峯; 佐々木, 直樹; 石井, 三都夫; 猪熊, 壽. |
| 分娩後5か月経過している2歳8カ月齢(症例1)および分娩後6か月経過している3歳0カ月齢(症例2) ホルスタイン種雌乳牛が、食欲不振、泌乳量減少、頻拍、心雑音、頚静脈怒張~拍動等の症状を呈し、循環器の疾患が疑われた。症例lでは心臓超音波検査によりまた症例2では病理検査にて心室中隔欠損が確認された。痩削、頚静脈拍動、頻脈などの循環器症状に加えて、心雑音の聴取をみた場合は、分娩後数カ月を経過した成牛であっても、心内膜炎のほかに心奇形も考慮し、診断には超音波検査を行うことが有効と考えられた。 |
| Ano: 2008 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2770 |
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| 佐藤, 巌紀; 西村, 麻紀; 三好, 雅史; 川本, 恵子; 古林, 与志安; 磯村, 洋; 宮原, 和郎; SATO, Genki; NISHIMURA, Maki; MIYOSHI, Masahumi; KAWAMOTO, Keiko; KOBAYASHI, Yoshiyasu; ISOMURA, Hiroshi; MIYAHARA, Kazurou. |
| 下唇の腫脹と下顎リンパ節の腫脹を伴った1 2 歳のT 細胞型皮膚型リンパ腫のシーズー犬に対してロムスチン （CCNU）による治療を行ったが効果は認められなかった．そこで，1回4Gyを2日おきに計5回，総線量20Gyで放射 線治療を実施したところ，腫脹の軽減が認められた．その後，飼い主希望により，積極的な治療は行わなかったが，数 回の放射線治療のたびに，改善が認められた．最終的に下唇と下顎リンパ節の腫瘤が増大し，第234 病日に斃死した．We administered lomustine (CCNU) to a 12-year-old Shih Tzu with T-cell type cutaneous lymphoma with swelling of the lower lip and mandibular lymph node. The treatment was ineffective and there was no reduction in the swelling in either area. Next, we carried out five radiation treatments (4Gy once every two days) with a total dose of radioactivity of 20Gy. Following the wishes of the owner, we did not perform further treatment. However, after several radiation treatments, there was a noticeable reduction in the swelling of the lower lip and... |
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Palavras-chave: 皮膚型リンパ腫; ロムスチン（CCNU）; 放射線治療; Cutaneous lymphoma; Lomustine (CCNU); Radiationtherapy. |
| Ano: 2010 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2940 |
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| Registros recuperados: 26 | |
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