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| Registros recuperados: 943 | |
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| Mukund,H; Gawade,SP. |
| Wasp venom is mixture of complex proteins that have several physical and pharmacological properties. The photochemical detoxification of Vespa orientalis venom is expected to generate photooxidized venom sac extract (PVSE). Antigenically active PVSE is obtained by exposing the venom sac extract (VSE) of Vespa orientalis to ultraviolet radiation in the presence of methylene blue. The aim of the present work was to evaluate the effect of PVSE on learning and memory of rats. Detoxification of PVSE was evident since treated mice had longer survival time than the group of mice treated with VSE. Photooxidized VSE of V. orientalis revealed enhancement on learning and memory by shortening the time to reach food (TRF) in T-maze. In a 28-day study with rats, we... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Vespa venom; Photochemical processes; Learning; Memory; Maze learning. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000400009 |
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| Lee,SW; Najiah,M; Wendy,W; Nadirah,M; Faizah,SH. |
| A total of 40 bacteria have been successfully isolated from internal organs of the American bullfrog (Rana catesbeiana) raised in Malaysia, namely, eight isolates of Aeromonas spp., 21 of Edwardsiella spp., six of Flavobacterium spp. and five of Vibrio spp. In terms of antibiotic susceptibility testing, each isolate was tested against 21 antibiotics, resulting in 482 (57.3%) cases of sensitivity and 61 (7.3%) cases of partial sensitivity. Meanwhile, 297 (35.4%) bacterial isolates were registered as resistant. The multiple antibiotic resistance (MAR) index of each bacterial species indicated that bacteria from raised bullfrogs have been exposed to tested antibiotics with results ranging from 0.27 to 0.39. Additionally, high percentages of heavy metal... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rana catesbeiana; Antibiogram; Heavy metal resistance; Multiple antibiotic resistance; Aeromonas spp.; Edwardsiella spp.; Flavobacterium spp.; Vibrio spp. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000200016 |
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| Sette,Christiane Salgado; Wachholz,Patrick Alexander; Masuda,Paula Yoshiko; Figueira,Renata Borges Fortes da Costa; Mattar,Fernanda Rodrigues de Oliveira; Ura,Deise Godoy. |
| AbstractThe infection by Mycobacterium marinum in humans is relatively uncommon. When it occurs, it mainly affects the skin, usually with a chronic, indolent and benign evolution. The diagnosis requires a high index of suspicion, and a significant delay may be observed between the first symptoms to the final diagnosis. This present case reports a M. marinum infection in an immunocompetent patient that had a chronic undiagnosed injury on the dominant hand for at least five years. The patient had several medical consultations, without proper suspicion, hampering adequate diagnostic investigation. Histopathology detected tuberculoid granulomas, but showed no acid-fast bacilli. The culture in appropriate medium and the polymerase chain reaction-restriction... |
| Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Mycobacterium infections; Mycobacterium marinum; Case report; Granuloma. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992015000100412 |
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| Silva,R. J.; Andrade,P. A.; Monteiro e Silva,H. A.; Rossellini,M.; Barrella,T. H.. |
| Haplometroides buccicola (Trematoda, Digenea, Plagiorchiidae) was reported in the mouth and oesophagus of Phalotris lativittatus (Serpentes, Colubridae) from Botucatu, São Paulo State, Brazil. This is the first report on the occurrence of H. buccicola parasitizing P. lativittatus. The Haplometroides genus was also discussed and the most important morphological characters for the identification of the species H. buccicola and H. odhneri are presented. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Haplometroides buccicola; Trematoda; Plagiorchiidae; Phalotris lativitattus; Serpentes; Colubridae. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992005000300013 |
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| Squaiella-Baptistão,Carla Cristina; Magnoli,Fábio Carlos; Marcelino,José Roberto; Sant’Anna,Osvaldo Augusto; Tambourgi,Denise V.. |
| Abstract Background Among other applications, immunotherapy is used for the post-exposure treatment and/or prophylaxis of important infectious diseases, such as botulism, diphtheria, tetanus and rabies. The effectiveness of serum therapy is widely proven, but improvements on the immunoglobulin purification process and on the quality control are necessary to reduce the amount of protein aggregates. These may trigger adverse reactions in patients by activating the complement system and inducing the generation of anaphylatoxins. Herein, we used immunochemical methods to predict the quality of horse F(ab′)2 anti-botulinum AB, anti-diphtheric, antitetanic and anti-rabies immunoglobulins, in terms of amount of proteins and protein aggregates. Methods Samples... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Heterologous immunoglobulin; F(ab′)2 fragment; Antitoxins; Anti-rabies; Protein profile; Complement system. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992018000100309 |
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| Cheng,Chin-Lung; Mao,Yan-Chiao; Liu,Po-Yu; Chiang,Liao-Chun; Liao,Shu-Chen; Yang,Chen-Chang. |
| Abstract Background Deinagkistrodon acutus envenomation is associated with severe hematological and wound complications but is rarely described. Case presentation Herein, we report three cases of victims bitten by D. acutus and indicate that rapid-onset severe coagulopathy and thrombocytopenia are distinct features of D. acutus snakebite, which are not observed in other crotaline snakebites (i.e., Trimeresurus stejnegeri and Protobothrops mucrosquamatus) in Taiwan. The toxic effects could occur as early as 2 to 3 h following D. acutus envenomation and persist if the administration of specific antivenom is delayed or even not commenced. Based on our findings, 2 to 4 vials of specific antivenom as the first dose should be administered to victims and... |
| Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Coagulopathy; Thrombocytopenia; Envenomation; Deinagkistrodon acutus; Snakebite. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992017000100504 |
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| Troiano,J. C.; Gould,E. G.; Gould,I.. |
| A comparative study on the sensitivity of erythrocytes from different vertebrate species (avian, mammalian and reptilian) to the hemolytic action caused by cardiotoxin isolated from Naja naja atra venom was carried out. Cardiotoxin was able to induce direct hemolysis in washed erythrocytes from several animals, except for llama. The EC50 values from hemolysis of the most sensitive (cat) and the most resistant (snake) animal varied approximately tenfold. According to the cell behavior, it was possible to characterize four types of behavior: The first was observed in cat, horse and human cells; the second in rat, rabbit and dog erythrocytes; and the third only in llama erythrocytes, which were resistant to cardiotoxin concentrations up to 300 µg/ml. Finally,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hemolysis; Cobra; Venom; Erythrocytes; Animals. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000100004 |
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| Parida,Siba Prasad; Dutta,Sushil Kumar; Pal,Arttatrana. |
| Background : Hematology and plasma biochemistry parameters are useful in the assessment and management of snake physiological status. Although reference ranges are readily available for many snake species, they are lacking for most venomous ophidians. We determined hematology and plasma biochemistry reference ranges for the wild-caught Indian cobra, Naja naja.Results : Blood samples, taken from the ventral tail vein, were assessed for erythrocyte count, total leukocyte count, hemoglobin concentration, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration, considering the sex of snakes. Results revealed the erythrocyte numbers (male, 390000 ± 12503.33/mm3 and female, 347500 ± 7505.55/mm3), shapes and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Reference range; Snake; Naja naja; Hematology; Plasma biochemistry. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200320 |
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| Nencioni,ALA; Barreto,SA; Lebrun,I; Florio,JC; Lourenço,GA; Dorce,VAC. |
| TsTX is an α-type sodium channel toxin that stimulates the discharge of neurotransmitters from neurons. In the present study we investigated which neurotransmitters are released in the hippocampus after TsTX injection and if they are responsible for electrographic or histopathological effects. Microdialysis revealed that the toxin increased glutamate extracellular levels in the hippocampus; however, levels of gamma-aminobutyric acid (GABA), glycine, 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and 3,4-dihydroxyphenylacetic acid (DOPAC) were not significantly altered. Neurodegeneration in pyramidal cells of hippocampus and electroencephalographic alterations caused by the toxin were blocked by pretreatment with riluzole, a glutamate release... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Scorpion toxin; Microdialysis; Hippocampus; Neurotransmitters; Neurodegeneration; Riluzole. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000200007 |
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| Huazhang,L; Wen-xue,L; Quan-xin,Z; Guang-yu,Y; Jun-tao,L; Li,M; Wei,Z. |
| To evaluate scallop safety in the Guangzhou seafood market, contents of shellfish toxins in adductor muscle, mantle skirts, gills and visceral mass of scallops were examined using enzyme-linked immunosorbent assay (ELISA) and mouse unit assay. The results showed that: paralytic shellfish poisoning contents were up to 37.44 μg/100 g by ELISA and 319.99 MU/100 g by mouse unit assay, which did not exceed the limits of national standards (80 μg/100g and 400 MU/100 g); the contents of diarrhetic shellfish poisoning were 142.04 μg/100g and 0.2 MU/100 g, which exceeded the national standard limits (60 μg/100g); neurotoxic shellfish poisoning was undetectable; the contents of amnesic shellfish poisoning reached 220.12 μg/100g (no... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Paralytic shellfish poisoning; Diarrheic shellfish poisoning; Neurotoxic shellfish poisoning; Amnesic shellfish poisoning; Enzyme-linked immunosorbent assay; Mouse unit assay. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000100010 |
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| Erdeş,Efe; Doğan,Tuğba Somay; Coşar,İlhan; Danışman,Tarık; Kunt,Kadir Boğaç; Şeker,Tamay; Yücel,Meral; Özen,Can. |
| Background Scorpion venoms are rich bioactive peptide libraries that offer promising molecules that may lead to the discovery and development of new drugs.Leiurus abdullahbayrami produces one of the most potent venoms among Turkish scorpions that provokes severe symptoms in envenomated victims.Methods In the present study, the peptide profile of the venom was investigated by electrophoretic methods, size-exclusion and reversed-phase chromatography and mass spectroscopy. Cytotoxic and antimicrobial effects were evaluated on a breast cancer cell line (MCF-7) and various bacterial and fungal species.Results Proteins make up approximately half of the dry weight of L. abdullahbayrami crude venom. Microfluidic capillary electrophoresis indicated the presence of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Scorpion venom; Toxin; Peptide; Leiurus abdullahbayrami; Microfluidic capillary; Electrophoresis; Peptidomics; Venomics; Cytotoxicity; Antimicrobial activity; Turkey. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200338 |
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| Quinet,Y; Vieira,RHSF; Sousa,MR; Evangelista-Barreto,NS; Carvalho,FCT; Guedes,MIF; Alves,CR; de Biseau,JC; Heredia,A. |
| Crematogaster ants use their contact venoms to compete with other ants. Although those venoms are used primarily as repellent and toxic secretions, they may have other functions. The present study aimed to test the antibacterial property of abdominal venom of three neotropical Crematogaster ant species (C. distans, C. pygmaea and C. rochai) against gram-negative (Escherichia coli and Pseudomonas aeruginosa) and gram-positive (Enterococcus faecalis and Staphylococcus aureus) bacteria. Sterile filter paper was soaked with C. distans, C. pygmaea or C. rochai crude venom and placed on an agar dish that was inoculated with bacterial suspensions. The agar dish was incubated overnight at 37ºC and examined for zones of growth inhibition. For each tested venom and... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Hymenoptera; Formicidae; Crematogaster; Sting apparatus; Contact venoms. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992012000400013 |
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| Registros recuperados: 943 | |
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