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Clinical and laboratory profile of HIV-positive patients at the moment of diagnosis in Bahia, Brazil BJID
Sá,Márcia Sampaio; Sampaio,Julio; Haguihara,Thiago; Ventin,Fernando Oak; Brites,Carlos.
In Brazil, current trends of the AIDS epidemic include an increase in transmission through heterosexual contact, predominantly from men to women, with more cases of AIDS in women and more children contaminated by vertical transmission. There is also a high proportion of cases in poor people or people living in small towns. HIV-infected patients with high levels of immunodeficiency are frequently hospitalized after their first visit to the clinic due to opportunistic infections, characteristic of advanced disease. This study characterized the clinical and laboratory pattern of AIDS in a sample of patients attended for the first time in the AIDS clinic of the Federal University of Bahia Hospital (HUPES) in Salvador, Brazil. We revised medical charts of cases...
Tipo: Info:eu-repo/semantics/article Palavras-chave: AIDS; HIV infection; Stage of disease; Brazil.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000400004
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Effect of pathogenic yeasts on human platelet aggregation BJID
Neiva,Teresinha de Jesus Carvalho; Santos,Jairo Ivo dos.
We investigated the effects of Candida albicans, Cryptococcus neoformans and the respective culture supernatants on human platelet aggregation (PA). Both yeasts were unable to aggregate the platelets directly. On the other hand, cells of these yeasts significantly (P < 0.01) inhibited PA at concentrations equal to or higher than 1 x 10(6) cells/mL for C. albicans and equal to or higher than 1 x 10(5) cells/mL for C. neoformans. When the supernatants of one-week broth cultures were added to the activated platelets no inhibition in aggregation was observed. Apparently somatic components of these yeasts, but not their metabolic products, exert an antagonistic effect on the aggregation of human platelets, possibly aiding the fungi in their evasion of the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Candida albicans; Cryptococcus neoformans; Platelet aggregation.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000600003
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Adolescents growing with HIV/AIDS: experiences of the transition from pediatrics to adult care BJID
Machado,Daisy Maria; Galano,Eliana; de Menezes Succi,Regina Célia; Vieira,Carla Maria; Turato,Egberto Ribeiro.
Abstract The main objective of this work is to describe the formation of the Transition Adolescent Clinic (TAC) and understand the process of transitioning adolescents with HIV/AIDS from pediatric to adult care, from the vantage point of individuals subjected to this process. A qualitative method and an intentional sample selected by criteria were adopted for this investigation, which was conducted in São Paulo, Brazil. An in-depth semi-structured interview was conducted with sixteen HIV-infected adolescents who had been part of a transitioning protocol. Adolescents expressed the need for more time to become adapted in the transition process. Having grown up under the care of a team of health care providers made many participants have reluctance toward...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV; AIDS; Health care transition; Adolescent.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000300002
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Clinical investigation for infections caused by Enterobacteriaceae in intensive care unit of Anhui, China BJID
Sun,Jing; Hu,Li-Fen; Wang,Min; Shi,Wei; Xu,Xi-Hai; Cheng,Jun; Ma,Tai; Luo,Xiao-Ming; Wang,Zhong-Xin; Ye,Ying; Li,Jia-Bin.
Tipo: Info:eu-repo/semantics/other
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000100023
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Parkinsonism in HIV infected patients during antiretroviral therapy – data from a Brazilian tertiary hospital BJID
Dehner,Luis Filipe; Spitz,Mariana; Pereira,João Santos.
Abstract Introduction Advances in the treatment of HIV infection in the last decades have increased life expectancy of these patients and raise the question of what kind of effect chronic infection and its treatment might exert on the behavior of age-related conditions such as neurodegenerative diseases. Patient data We performed a retrospective analysis of patients’ records to assess the frequency of the association between HIV infection and parkinsonian symptoms in our hospital population. Among 249 records we identified four individuals with reported parkinsonian symptoms initiated after HIV diagnosis. Three of them had no other identifiable cause of secondary parkinsonism. All had symptom onset before the age of 60. Based on this study sample one...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Parkinsonism; HIV; Antiretroviral therapy.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000500499
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Quality of life, risk behaviors and depression among carriers of hepatitis C virus and human T-cell lymphotropic virus type 1: a comparative study BJID
Henrique-Araújo,Ricardo; Quarantini,Lucas C.; Caribé,André C.; Argolo,Felipe C.; Jesus-Nunes,Ana Paula; Morais-de-Jesus,Mychelle; Dantas-Duarte,Adriana; Moreira,Tayne Miranda; Oliveira,Irismar Reis de.
Abstract Human T-cell lymphotropic virus type 1 (HTLV-1) has low prevalence rates, but is endemic in some regions of the world. It is usually a chronic asymptomatic infection, but it can be associated with serious neurologic and urinary conditions. Hepatitis C virus (HCV) is broadly spread out worldwide. The majority of these infections have a chronic course that may progress to cirrhosis and hepatocellular carcinoma. Objectives: To compare sociodemographic and mental health (risk behaviors, depression, and suicide) aspects, and quality of life among patients with HCV or HTLV-1. Methods: Observational, comparative and cross-sectional study involving outpatients with HCV or HLTV-1 infection. Sociodemographic characteristics, risk behaviors and quality of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatitis C virus; Human T-cell lymphotropic virus type 1; Quality of life; Risk behaviors; Depression; Suicide.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000400224
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Prevalence of potentially pathogenic free-living amoebae from Acanthamoeba and Naegleria genera in non-hospital, public, internal environments from the city of Santos, Brazil BJID
Teixeira,Lais Helena; Rocha,Silvana; Pinto,Rosa Maria Ferreiro; Caseiro,Marcos Montani; Costa,Sergio Olavo Pinto da.
Acanthamoeba and Naegleria species are free-living amoebae (FLA) found in a large variety of natural habitats. The prevalence of such amoebae was determined from dust samples taken from public non-hospital internal environments with good standards of cleanliness from two campuses of the same University in the city of Santos (SP), Brazil, and where young and apparently healthy people circulate. The frequency of free-living amoebae in both campuseswas 39% and 17% respectively, with predominance of the genus Acanthamoeba. On the campus with a much larger number of circulating individuals, the observed frequency of free-living amoebae was 2.29 times larger (P< 0.00005). Two trophozoite forms of Naegleria fowleri, are the only species of this genus known to...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Free - living amoebae; Acanthamoeba spp.; Naegleria spp.; Prevalence; Dust from internal environments; Brazil.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000600001
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Antimicrobial susceptibility, virulence determinant carriage and molecular characteristics of Staphylococcus aureus isolates associated with skin and soft tissue infections BJID
Yu,Fangyou; Liu,Yunling; Lv,Jinnan; Qi,Xiuqin; Lu,Chaohui; Ding,Yu; Li,Dan; Liu,Huanle; Wang,Liangxing.
ABSTRACT A better understanding of the antimicrobial susceptibility, carriage of virulence determinants and molecular characteristics of Staphylococcus aureus isolates associated with skin and soft tissue infections (SSTIs) may provide further insights related to clinical outcomes with these infections. From January 2012 to September 2013, a total of 128 non-duplicateS. aureus isolates were recovered from patients with SSTIs. All 128 S. aureus SSTI isolates carried at least five virulence genes tested. Virulence genes detected among at least 70% of all tested isolates included hld (100%), hla (95.3%),icaA (96.9%), clf (99.2%),sdrC (79.7%), sdrD (70.3%), andsdrE (72.7%). The prevalence of MRSA isolates with 10 virulence genes tested (54.4%, 31/56) was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Staphylococcus aureus; Skin and soft tissue infections; Molecular characteristic; Virulence genes.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000600614
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Treatment of patients infected with hepatitis C virus and presenting extrahepatic manifestations BJID
Tengan1,Fátima Mitiko; Barone,Antonio Alci.
Tipo: Info:eu-repo/semantics/other
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000700018
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Retraction notice to "The rapid and sustained responses of dendritic cells to influenza virus infection in a non-human primate model" [Braz. J. Infect. Dis. 18 (2014) 406-413] BJID
Jie,Zhijun; Sun,Wei; Wang,Shanze; Koster,Frederick; Li,Bilan; Harrod,Kevin S..
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000600677
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Early predictive efficacy of core antigen on antiviral outcomes in genotype 1 hepatitis C virus infected patients BJID
Feng,Bo; Yang,Rui-Feng; Zhang,Hai-Ying; Luo,Bi-Fen; Kong,Fan-Yun; Rao,Hui-Ying; Jin,Qian; Cong,Xu; Wei,Lai.
Response-guided therapy is of limited use in developing countries because hepatitis C virus RNA detection by sensitive molecular methods is time- and labor-consuming and expen- sive. We evaluated early predictive efficacy of serum hepatitis C virus core antigen kinetics on sustained virologic response in patients with genotype 1 hepatitis C virus during pegylated interferon plus ribavirin treatment. For 478 patients recruited, hepatitis C virus RNAs were detected at baseline, and at weeks 4, 12, 24, 48, and 72 using Cobas TaqMan. Architect hepatitis C virus core antigen was performed at baseline, and weeks 4 and 12. Predictive values of hepatitis C virus core antigen on sustained virologic response were compared to hepatitis C virus RNA. In the first 12...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatitis C; Genotype 1; HCV core antigen; HCV treatment.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000400390
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Human herpesvirus 6A active infection in patients with autoimmune Hashimoto's thyroiditis BJID
Seyyedi,Noorossadat; Dehbidi,Gholamreza Rafiei; Karimi,Mozhgan; Asgari,Amir; Esmaeili,Babak; Zare,Farahnaz; Farhadi,Ali; Dabbaghmanesh,Mohammad Hossein; Saki,Forough; Behzad-Behbahani,Abbas.
ABSTRACT Background: Hypothyroidism due to Hashimoto's thyroiditis (HT) is the commonest autoimmune endocrine illness in which antibodies against thyroid organ result in inflammation. The disease has a complex etiology that involves genetic and environmental influences. Viral infections may be involved in triggering of the disease as their molecular mimicry enhance autoimmune responses. Human herpesvirus-6 (HHV-6) is recognized for its contribution to some autoimmune diseases. Objective: In the current study, the prevalence of HHV-6 active infection in patients with HT and with non-autoimmune thyroid disorders were compared with patients with euthyroidism. In addition, a correlation between presence of HHV-6 infections and HT was investigated. Methods:...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Human herpesvirus 6; Prevalence; Hashimoto disease; Autoimmune diseases.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000600435
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Proposal of a clinical score to stratify the risk of multidrug-resistant gram-negative rods bacteremia in cancer patients BJID
Carena,Alberto A.; Laborde,Ana; Roccia-Rossi,Inés; Palacios,Cynthia J.; Jordán,Rosana; Valledor,Alejandra; Nenna,Andrea; Costantini,Patricia; Dictar,Miguel; Herrera,Fabián.
ABSTRACT Introduction: Multidrug-resistant gram-negative rods (MDR GNR) represent a growing threat for patients with cancer. Our objective was to determine the characteristics of and risk factors for MDR GNR bacteremia in patients with cancer and to develop a clinical score to predict MDR GNR bacteremia. Material and Methods: Multicenter prospective study analyzing initial episodes of MDR GNR bacteremia. Risk factors were evaluated using a multiple logistic regression (forward-stepwise selection) analysis including variables with a p < 0.10 in univariate analysis. Results: 394 episodes of GNR bacteremia were included, with 168 (42.6 %) being MDR GNR. Five variables were identified as independent risk factors: recent antibiotic use (OR = 2.8, 95 % CI...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bacteremia; Cancer; Multidrug-Resistant gram-negative rods.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702020000100034
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Distribution of serotypes and evaluation of antimicrobial susceptibility among human and bovine Streptococcus agalactiae strains isolated in Brazil between 1980 and 2006 BJID
Pinto,Tatiana Castro Abreu; Costa,Natália Silva; Souza,Aline Rosa Vianna; Silva,Ligia Guedes da; Corrêa,Ana Beatriz de Almeida; Fernandes,Flavio Gimenis; Oliveira,Ivi Cristina Menezes; Mattos,Marcos Corrêa de; Rosado,Alexandre Soares; Benchetrit,Leslie Claude.
Streptococcus agalactiae is a common agent of clinical and subclinical bovine mastitis and an important cause of human infections, mainly among pregnant women, neonates and nonpregnant adults with underlying diseases. The present study describes the genetic and phenotypic diversity among 392 S. agalactiae human and bovine strains isolated between 1980 and 2006 in Brazil. The most prevalent serotypes were Ia, II, III and V and all the strains were susceptible to penicillin, vancomycin and levofloxacin. Resistance to clindamycin, chloramphenicol, erythromycin, rifampicin and tetracycline was observed. Among the erythromycin resistant strains, mefA/E, ermA and, mainly, ermB gene were detected, and a shift of prevalence from the macrolide resistance phenotype...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Streptococcus agalactiae; Pulsed field gel electrophoresis; Epidemiology; Serotyping; Resistance profile.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000200003
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Bedbugs (Cimicidae infestation): the worldwide renaissance of an old partner of human kind BJID
Criado,Paulo Ricardo; Belda Junior,Walter; Criado,Roberta Fachini Jardim; Silva,Roberta Vasconcelos e; Vasconcellos,Cidia.
Bedbugs have been known as a human parasite for thousands of years, but scientific studies about this insect are recent and limited. Cimex lectularius, the common bedbug, was a well-known parasite in human dwellings until the end of the Second World War. Nowadays, bedbugs are considered uncommon in the industrialized world. Anecdotal reports suggest that bedbugs are getting more common in the United States, Canada, and United Kingdom. In Brazil, there are few reports about bedbug infestations in the literature. The aim of this article was to alert physicians, especially in Brazil, about this ectoparasitosis, including aspects of the bedbug biology, their parasitism in human host, treatment and prophylaxis.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hemiptera; Bedbugs; Cimex lectularius; Pyrethrins; DDT.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000100014
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First characterization of a Providencia stuartii clinical isolate from a Tunisian intensive care unit coproducing VEB-1-a, OXA-2, qnrA6 and aac(6')-Ib-cr determinants BJID
Mahrouki,Sihem; Chihi,Hela; Bourouis,Amel; Moussa,Mohamed Ben; Belhadj,Omrane.
A clinical Providencia stuartii isolate SM662 was recovered from a patient hospitalized in the intensive care unit at the Military hospital, Tunisia. This isolate was resistant to penicillins, cephalosporins, aminoglycosides and fluoroquinolones. A marked in vitro synergy between ceftazidime or cefotaxime and amoxicillin-clavulanic acid on Mueller-Hinton agar plates suggested the presence of an extended-spectrum-β-lactamase. In addition, an unusual synergy was found between cefepime or aztreonam, and cefoxitin or imipenem on a double disk synergy test suggesting a VEB-type extended-spectrum-β-lactamase. The characterization of β-lactamases and associated resistance genes was performed by isoelectric focusing, polymerase chain reaction and nucleotide...
Tipo: Info:eu-repo/semantics/other Palavras-chave: ESBL Providencia stuartii; QnrA6; Aac(6')-Ib-cr.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000200211
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2011 for BJID - some good news and acknowledgements BJID
Brites,Carlos.
Tipo: Info:eu-repo/semantics/other
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000600001
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Therapy with radio-attenuated vaccine in experimental murine visceral leishmaniasis showed enhanced T cell and inducible nitric oxide synthase levels, suppressed tumor growth factor-beta production with higher expression of some signaling molecules BJID
Datta,Sanchita; Roy,Syamal; Manna,Madhumita.
Background:Visceral leishmaniasis (VL) or Kala-Azar (KA) is one of the most deadly forms of disease among all neglected tropical diseases. There are no satisfactory drugs or vaccine candidates available for this dreaded disease. Our previous studies showed promising therapeutic and prophylactic efficacy of the live, radio-attenuated parasites through intramuscular (I.M.) and intraperitoneal (I.P.) route in BALB/c mice model.Methods:The T-cell proliferation level, the mRNA expression level of inducible nitric oxide synthase (iNOS) and tumor growth factor-beta (TGF-β) genes and finally the phosphorylation levels of phosphoinositide dependent kinase 1 (PDK1), phosphoinositide 3 kinase (PI3K) and p38 mitogen activated protein kinase (p38MAPK) molecules were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Radio-attenuated Leishmania; Parasites; PDK1; PI3K; P38MAPK.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000100036
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Time of catheter removal in candidemia and mortality BJID
Nucci,Marcio; Braga,Paula Rocha; Nouér,Simone A.; Anaissie,Elias.
ABSTRACT Background: The impact of central venous catheter (CVC) removal on the outcome of patients with candidemia is controversial, with studies reporting discrepant results depending on the time of CVC removal (early or any time during the course of candidemia). Objective: Evaluate the effect of time to CVC removal, early (within 48 h from the diagnosis of candidemia) vs. removal at any time during the course of candidemia, on the 30-day mortality. Methods: Retrospective cohort study of 285 patients with candidemia analyzing CVC removal within 48 h (first analysis) or at any time (second analysis). Results: A CVC was in place in 212 patients and was removed in 148 (69.8%), either early (88 patients, 41.5%) or late (60 patients, 28.3%). Overall, the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Candidemia; Central venous catheter; Mortality; Multivariate analysis; Candida.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000600455
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Characterization of the high-risk human papillomavirus infection in Jining, China BJID
Jia,Yinfeng; Guo,Huan; Liu,Feifei; Zhou,Guangqi; Dong,Haixin; Bi,Ling; Jia,Jialin; Sun,Hui.
Tipo: Info:eu-repo/semantics/other
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000200029
Registros recuperados: 2.072
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