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| Registros recuperados: 239 | |
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| LEITE,C.V.S.; NARESSE,L.E.; ARANTES,H.L.; LOPES,A.F.; THOMAZINI-SANTOS,I.A.; GIANNINI,M.J.S; MERCADANTE,M.C.; BARRAVIERA,B.; KOBAYASI,S.. |
| The objective of this study was to evaluate the efficacy of fibrin adhesive made up of snake venom and bubaline fibrinogen by rat colon anastomosis. Eighty rats were randomly assigned into 2 experimental groups: GI control (anastomosis with extramucous interrupted suture) and GII (repair suture + fibrin glue). The animals were studied at the following 4 times: T0 preoperative, T1 7th day postoperative, T2 14th day postoperative, and T3 21 st day postoperative. The macroscopic characteristics of the intestinal segment open and closed anastomosis and the bursting strength of the anastomosed segments were observed at each of the above times. The results showed that the anastomosed segments coapted and there was no difference in the bursting strength... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Fibrin glue; Experimental healing; Bursting strength; Experimental anastomosis; Snake venom; Colon anastomosis. |
| Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302000000200004 |
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| ROODT,A.R. de; DOLAB,J. A.; SEGRE,L.; SIMONCINI,C.; HAJOS,S. E.; FERNANDEZ,T.; DOKMETJIAN,J. C.; LITWIN,S.; ACCATTOLI,C.; VIDAL,J. C.. |
| The immunochemical reactivity and neutralizing capacity of polyvalent Vipera antivenom (Vipera ammodytes, Vipera aspis, Vipera berus, Vipera lebetina, and Vipera xanthina) were tested on the enzymatic and biological activities of Crotalus durissus terrificus and the following Bothrops venoms from Argentina (Bothrops alternatus, Bothrops ammodytoides, Bothrops neuwiedii, Bothrops jararaca, Bothrops jararacussu, and Bothrops moojeni). The Vipera antivenom reacted weakly when tested by double immunoprecipitation (DIP) and reacted with all the venoms when tested by ELISA. Several components in all the venoms studied were recognized in Western blots. Vipera antivenom deactivated to different degrees in vitro procoagulant, (indirect) hemolytic, and proteolytic... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antivenom; Vipera; Bothrops; Crotalus; Cross-reactivity; Cross-neutralization. |
| Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301999000100006 |
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| ABE,T.; SUMATORA,M.; HASHIMOTO,Y.; YOSHIHARA,J.; SHIMAMURA,Y.; FUKAMI,J.. |
| Cardioleputin, a new cardioactive toxin, was purified from a stonefish venom using column chromatographies. The purified toxin was found to be an unstable protein that was susceptible to heat and freeze-thawing. This protein showed to have a molecular size of 46,000 daltons, and its amino acid composition was rich in serine and glycine, but low in basic amino acids. The crude venom induced a sudden drop in blood pressure and heart rate of rats right after administration. Both the blood pressure and heart rate returned to their original values as time elapsed, and thereafter continued to show a gradual decrease. In addition, crude venom actively affected the contractile response and suppressed the heart rate of guinea pig atria. The purified toxin caused... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cardioactive toxin; Cardioleputin; Synanceja verrucosa. |
| Ano: 1996 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301996000200006 |
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| GUIDOLIN,R.; STEPHANO,M. A.; MORAIS,J. F.; SAKAGUTI,E. H.; PRADO,S. M. A.; FRATELLI,F.; VANCETTO,M. D. C.; HIGASHI,H. G.. |
| The present investigation reveals the possibility of simultaneous immunization of horses with Bothrops or Crotalus snake venoms and Tetanus antigens for the production of anti-Bothrops-Tetanus or anti-Crotalus-Tetanus mixed serum, with high titers of the respective specific antibodies. Bothrops antivenoms with an average neutralizing titer of 4.16 mg venom/ml were obtained from plasma of horses with titers lower than 0.5 mg venom/ml when Tetanus antigens were not used. This suggests the existence of a synergism between Bothrops venoms and Tetanus antigens in the stimulation of the antibody response. The pooled plasma of the animals had a neutralizing titer of 21.0 mg/ml reference Bothrops venoms and 3,300 IU/ml to Tetanus antigens after purification by... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antivenoms; Immunization; Bothrops; Tetanus. |
| Ano: 1998 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301998000100007 |
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| BACH,E. E.; KIMATI,H.. |
| Low molecular weight metabolites produced by Bipolaris bicolor, Bipolaris sorokiniana, and Drechslera tritici-repentis are considered to be toxins that facilitate disease in wheat cultivars. Several such toxins were isolated from these fungi. Electrophoresis demonstrated bands of proteins that reduced shoot inhibition in susceptible plants but not in resistant plants. Chlorophyll content was reduced during the first 10 hours of light in the susceptible plants and after 18 hours in the resistant plants. The enzyme beta-1,3-glucanase increased in the resistant plants after treatment with toxins, but in the susceptible plants this enzyme decreased compared to the control. This suggests that the toxin was a protein and the susceptible plants needed other... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Toxin; Wheat pathogens; Protein toxin. |
| Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301999000200006 |
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| Oshima-Franco,Y.; Leite,G. B.; Valério,A. A.; Hyslop,S.; Andriao-Escarso,S.; Giglio,J. R.; Prado-Franceschi,J.; Cruz-Höfling,M. A.; Rodrigues-Simioni,L.. |
| Bothrops jararacussu venom and its major toxin bothropstoxin-I (BthTX-I) possess myotoxic and neurotoxic properties. The efficacy of a rabbit antivenom raised against B. jararacussu venom in the neutralization of physiological, biochemical, and morphological changes induced by the venom and its major toxin BthTX-I was studied in mouse isolated phrenic nerve-diaphragm (PND) and extensor digitorum longus (EDL) preparations. The times required for 50% neuromuscular blockade in PND and EDL preparations for venom were 70+11.5 (S.E.M., n=5) min and 58+8 (n=16) (50 mu g/mL), and for BthTX-I 31+6 (n=3) min and 30+3 (n=5) min (20 mu g/mL), respectively. After 120 min incubation, creatine kinase (CK) concentrations in solution containing the EDL preparations were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bothrops venom; Myotoxin; Neutralization; Neuromuscular junction; Histological analysis; Bothrops jararacussu. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302002000200004 |
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| SARTORI FILHO,R.; PRESTES,N. C.; THOMAZINI,I. A.; MENDES-GIANNINI,M. J.; TOSCANO,E.; CANAVESSI,A. M. O.; BARRAVIERA,B.. |
| Sequelae due to testicular biopsy such as hemorrhage, adhesion and fibrosis may be limiting factors to the use of this surgical procedure. Fibrin glue (FG) derived from snake venom was used to minimize these sequelae, as well as to evaluate its healing property in tunica vaginalis and scrotal skin of rams. Applicability of fibrin glue derived from snake venom was tested in different tissues of other animals such as in sciatic nerve and colon of rats and skin of rabbits. In the present study, 30 healthy adult rams were used. They were divided into 3 groups of 10 animals each as follows: G1: fibrin glue group (application of fibrin glue on puncture sites and skin incisions after bilateral testicular biopsy with a Tru-Cut needle); G2: swab/nylon group... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Fibrin tecidual adhesive; Snake venoms; Biopsy; Testicle; Ovine. |
| Ano: 1998 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301998000100003 |
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| FERNANDES Jr.,A.; SUGIZAKI,M.F.; FOGO,M.L.; FUNARI,S.R.C.; LOPES,C.A.M.. |
| The in vitro activity of propolis against 118 Staphylococcus aureus, 108 Escherichia coli, 60 Salmonella typhimurium, 50 Candida albicans, 23 Candida parapsilosis, 19 Candida tropicalis and 14 Candida guilliermondii isolated from human infections was studied by the agar dilution method. Among the bacteria, the Gram-negative were the least susceptible organisms showing minimal inhibitory concentration (MIC) for 90% of the strains tested ranging from 22.5 mg/ml - 10,2% V/V to 23.1 mg/ml - 10.5% V/V. The MIC's for Candida ranged from 0.80 mg/ml to > 11 mg/ml (0.40% V/V to > 5.0% V/V), the strains of C. parapsilosis being the least susceptible. The relative order of susceptibility among all isolates, was: S.aureus > C. tropicalis >... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Propolis; Antimicrobial activity; Bacteria; Yeast pathogens; Candida sp. |
| Ano: 1995 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301995000200003 |
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| FRANCO,R. L.; ROCHA,C. C.; JORGE,M. T.; RIBEIRO,L.A.. |
| In Brazil, more than 80% of venomous snakebites are caused by Bothrops and about 10% by Crotalus. This study evaluated 133 reported cases that occurred between 1994 and 1996 in the 52 municipalities covered by the Pouso Alegre Regional Health Center in southern Minas Gerais State. Most of the patients were male (89.5%). The most frequently attacked age bracket was that of people in their twenties, and the most frequently bitten anatomical regions were the lower limbs (77.7%), principally the feet (34.6%). Of the 124 cases stating the snake genus, 62.9% were caused by Crotalus and 37.1% by Bothrops. The conclusion of this study is that although the epidemiology of snakebites in Minas Gerais State is similar to other regions of the country, the percentage of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Crotalus; Snakebite; Brazil. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302001000100005 |
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| Registros recuperados: 239 | |
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