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Registros recuperados: 117
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The changing pattern of methicillin-resistant staphylococcus aureus clones in Latin America: implications for clinical practice in the region BJID
Rodríguez-Noriega,Eduardo; Seas,Carlos.
Methicillin-resistant Staphylococcus aureus (MRSA) clones belonging to the Brazilian, Pediatric, Cordobes/Chilean and New York/Japan clonal complexes are widely distributed across Latin America, although their individual distribution patterns and resistance to antimicrobial drugs are constantly changing. Furthermore, clones with increased virulence are beginning to appear more frequently both in hospital and community settings, and there is evidence that virulence factors can be transferred between hospital- and community-associated clones through recombination. These changing patterns have significant implications for clinical practice in the region. Most importantly, clinicians need to be aware of the changing antimicrobial resistance profile of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: MRSA; Clones; Molecular epidemiology; Latin America.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000800004
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Susceptibility rates in Latin American nations: report from a regional resistance surveillance program (2011) BJID
Jones,Ronald N.; Guzman-Blanco,Manuel; Gales,Ana C.; Gallegos,Belisario; Castro,Aura Lucia Leal; Martino,Marines Dalla Valle; Vega,Silvio; Zurita,Jeannete; Cepparulo,Mario; Castanheira,Mariana.
OBJECTIVE: To establish a resistance (R) surveillance program monitoring antimicrobial susceptibility patterns in Latin America (LATAM; Argentina [ARG], Brazil [BRA], Chile, Colombia [CBA], Costa Rica, Ecuador [ECU], Guatemala [GUA], Mexico [MEX], Panama [PAN], Peru, and Venezuela [VEN]). METHODS: In 2011, 4979 organisms were collected from 11 nations (20 laboratories) for susceptibility testing in a central laboratory design. Antimicrobials were tested by CLSI methods and results interpreted by CLSI and EUCAST breakpoints. Most common Gram-positive (Staphylococcus aureus [SA, 921], other staphylococci [CoNS; 299], enterococci [218], Streptococcus pneumoniae [SPN; 182], β-haemolytic streptococci [115]) and Gram-negative (E. coli [EC; 644], Klebsiella spp....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Latin America; Surveillance; Resistance; ESBL; Β-Lactamases.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000600009
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Ceftolozane-tazobactam activity against drug-resistant Enterobacteriaceae and Pseudomonas aeruginosa causing healthcare-associated infections in Latin America: report from an antimicrobial surveillance program (2013-2015) BJID
Pfaller,Michael A.; Shortridge,Dee; Sader,Helio S.; Gales,Ana; Castanheira,Mariana; Flamm,Robert K..
ABSTRACT This study evaluated the in vitro activity of ceftolozane-tazobactam and comparator agents tested against Latin American isolates of Enterobacteriaceae and Pseudomonas aeruginosa from patients with health care-associated infections. Ceftolozane-tazobactam is an antipseudomonal cephalosporin combined with a well-established β-lactamase inhibitor.A total of 2415 Gram-negative organisms (537 P. aeruginosa and 1878 Enterobacteriaceae) were consecutively collected in 12 medical centers located in four Latin American countries. The organisms were tested for susceptibility by broth microdilution methods as described by the CLSI M07-A10 document and the results interpreted according to EUCAST and CLSI breakpoint criteria. Results: Ceftolozane-tazobactam...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ceftolozane-tazobactam; Drug resistance; Enterobacteriaceae; P. aeruginosa; Latin America; Surveillance.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000600627
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Metabolic syndrome in HIV-infected patients receiving antiretroviral therapy in Latin America BJID
Alvarez,C; Salazar,R; Galindez,J; Rangel,F; Castañeda,ML; Lopardo,G; Cuhna,CA; Roldan,Y; Sussman,O; Gutierrez,G; Cure-Bolt,N; Seas,C; Carcamo,C; Castrillo,M.
OBJECTIVE: To evaluate the prevalence of and the associated factors for metabolic syndrome (MS) among Latin American HIV-infected patients receiving antiretroviral therapy (ART) using baseline data from the RAPID II study. METHODS: A longitudinal study to evaluate the metabolic profile, cardiovascular disease (CVD) risk and associated treatment practices to reduce this risk has been conducted in seven Latin American countries (the RAPID II study). Adult HIV patients with at least six months of RT were enrolled. MS was defined following ATP-III criteria. Demographic and anthropometric data, serum biochemical and clinical parameters were compared in patients with and without MS using bivariate and multivariate analysis. RESULTS: A total of 4,010 patients...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Metabolic syndrome (MS); HIV; ART; Latin America.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000300010
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Extended spectrum β-lactamase producers among nosocomial Enterobacteriaceae in Latin America BJID
Guzmán-Blanco,Manuel; Labarca,Jaime A.; Villegas,Maria Virginia; Gotuzzo,Eduardo.
To review the epidemiology of nosocomial extended spectrum β-lactamase-producing Enterobacteriaceae in Latin America, a systematic search of the biomedical literature (PubMed) was performed for articles published since 2005. Rates of nosocomial infections caused by extended spectrum β-lactamase-producing Enterobacteriaceae in Latin America have increased since 2005. Up to 32% of Escherichia coli and up to 58% of Klebsiella pneumoniae isolates are extended spectrum β-lactamase-positive, rates that are higher than in other world regions. From a region-wide perspective, 11-25% of E. coli isolates and 45-53% of K. pneumoniae isolates were nonsusceptible to third-generation cephalosporins. At the country level, there was a wide range in Enterobacteriaceae...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Escherichia coli; Klebsiella; Latin America; Bacterial resistance.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000400421
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Thermotolerance of Histoplasma capsulatum at 40 °C predominates among clinical isolates from different Latin American regions BJID
Sahaza,Jorge H.; Rodríguez-Arellanez,Gabriela; Canteros,Cristina E.; Reyes-Montes,María del Rocío; Taylor,Maria Lucia.
ABSTRACT The yeast phase of 22 Histoplasma capsulatum clinical isolates from Mexico, Argentina, Colombia, and Guatemala and three reference strains, one from Panama and two from the United States of America (USA), were screened for thermosensitivity characteristics using different analyses. Growth curves at 0, 3, 6, 12, 24, and 30 h of incubation at 37 and 40 °C, the growth inhibition percentage at 40 °C, and the doubling time at 37 and 40 °C were determined for all yeasts studied. Most of the isolates examined exhibited thermotolerant phenotypes at 40 °C, whereas a thermosensitive phenotype at 40 °C was only detected in the Downs reference strain from the USA. Growth inhibition values lower than 33.8% supported the predominance of the thermotolerant...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Latin America; H. capsulatum; Yeasts; Thermotolerance; Thermosensitivity.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702020000100044
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Ceftaroline activity tested against contemporary Latin American bacterial pathogens (2011) BJID
Flamm,Robert K.; Sader,Helio S.; Jones,Ronald N..
A total of 2484 target bacterial pathogens were collected (one per patient episode) from patients in 16 Latin American medical centers located in seven nations during 2011. Isolate identity was confirmed at a coordinating laboratory and susceptibility testing was performed for ceftaroline and comparator agents according to reference broth microdilution methods. A total of 30.0% of isolates were from respiratory tract, 29.4% from skin and skin structure, 21.4% from blood stream, 7.9% from urinary tract and 11.3% from other sites. Ceftaroline was active againstStaphylococcus aureus (42.8% MRSA) with 83.6% of the isolates at <1mg/L and all isolates at <2mg/L (MIC5090, 0.25/2mg/L). National MRSA rates ranged from a low of 28.8% in Colombia to a high of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ceftaroline; Latin America; AWARE.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000200187
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Activity of ceftaroline and comparators against pathogens isolated from skin and soft tissue infections in Latin America - results of AWARE surveillance 2012 BJID
Hoban,Daryl; Biedenbach,Douglas; Sahm,Daniel; Reiszner,Edina; Iaconis,Joseph.
ABSTRACT As part of the Assessing Worldwide Antimicrobial Resistance Evaluation (AWARE) surveillance program in 2012 the in vitro activity of ceftaroline and relevant comparator antimicrobials was evaluated in six Latin American countries (Argentina, Brazil, Chile, Colombia, Mexico and Venezuela) against pathogens isolated from patients with hospital associated skin and soft tissue infections (SSTIs). The study documented that ceftaroline was highly active (MIC90 0.25 mg/L/% susceptible 100%) against methicillin-susceptible Staphylococcus aureus, methicillin-resistant S. aureus (MIC90 2 mg/L/% susceptible 83.3%) and ß-hemolytic streptococci (MIC90 0.008-0.015 mg/L/% susceptible 100%). The activity of ceftaroline against selected species of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ceftaroline; Skin pathogens; Latin America.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000600596
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Relationship between viral load and behavioral measures of adherence to antiretroviral therapy in children living with human immunodeficiency virus in Latin America BJID
Duarte,Horacio A.; Harris,Donald Robert; Tassiopoulos,Katherine; Leister,Erin; Negrini,Silvia Fabiana Biason de Moura; Ferreira,Flávia Faleiro; Cruz,Maria Letícia Santos; Pinto,Jorge; Allison,Susannah; Hazra,Rohan.
Few studies have examined antiretroviral therapy adherence in Latin American children. Standardized behavioral measures were applied to a large cohort of human immunodeficiency virus-infected children in Brazil, Mexico, and Peru to assess adherence to prescribed antiretroviral therapy doses during the three days prior to study visits, assess timing of last missed dose, and evaluate the ability of the adherence measures to predict viral suppression. Time trends in adherence were modeled using a generalized estimating equations approach to account for possible correlations in outcomes measured repeatedly in the same participants. Associations of adherence with human immunodeficiency virus viral load were examined using linear regression. Mean enrollment age...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pediatric; ART; Adherence; Latin America.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000300263
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Treatment of methicillin-resistant Staphylococcus aureus in Latin America BJID
Luna,Carlos M; Rodríguez-Noriega,Eduardo; Bavestrello,Luis; Gotuzzo,Eduardo.
The global spread of methicillin-resistant Staphylococcus aureus (MRSA) means it is now a pathogen of worldwide public health concern. Within Latin America, MRSA is highly prevalent, with the proportion of S. aureus isolates that are methicillin-resistant on the rise, yet resources for managing the infection are limited. While several guidelines exist for the treatment of MRSA infections, many are written for the North American or European setting and need adaptation for use in Latin America. In this article, we aim to emphasize the importance of appropriate treatment of MRSA in the healthcare and community settings of Latin America. We present a summary of the available guidelines and antibiotics, and discuss particular considerations for clinicians...
Tipo: Info:eu-repo/semantics/article Palavras-chave: MRSA; Treatment; Antibiotic therapy; Latin America.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000800007
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Online continuing interprofessional education on hospital-acquired infections for Latin America BJID
Medina-Presentado,Julio C.; Margolis,Alvaro; Teixeira,Lucia; Lorier,Leticia; Gales,Ana C.; Pérez-Sartori,Graciela; Oliveira,Maura S.; Seija,Verónica; Paciel,Daniela; Vignoli,Rafael; Guerra,Silvia; Albornoz,Henry; Arteta,Zaida; Lopez-Arredondo,Antonio; García,Sofía.
Abstract Introduction: Latin America is a large and diverse region, comprising more than 600 million inhabitants and one million physicians in over 20 countries. Resistance to antibacterial drugs is particularly important in the region. This paper describes the design, implementation and results of an international bi-lingual (Spanish and Portuguese) online continuing interprofessional interactive educational program on hospital-acquired infections and antimicrobial resistance for Latin America, supported by the American Society for Microbiology. Methods: Participation, satisfaction and knowledge gain (through pre and post tests) were used. Moreover, commitment to change statements were requested from participants at the end of the course and three...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Internet; Continuing education; Interprofessional education; MOOC; Hospital-acquired infections; Latin America.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000200140
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Prevention strategies for methicillin-resistant Staphylococcus aureus (MRSA) in Latin America BJID
Alvarez,Carlos; Labarca,Jaime; Salles,Mauro.
After the first reports of the emergence of methicillin-resistant Staphylococcus aureus (MRSA) in the 1970s, numerous measures intended to prevent its transmission were initiated in hospitals. However, in most cases, large-scale measures failed to be implemented and the transmission of MRSA has since led to a global pandemic. Presently, doubts still remain about the best approach to prevent and control MRSA and more often than not, control measures are not implemented. Therefore, we review here the current situation in Latin America with respect to existing policies for control of MRSA, and evaluate the evidence for control measures in hospitals and the community. We look at the risk factors for infection and transmission of MRSA between hospital patients...
Tipo: Info:eu-repo/semantics/article Palavras-chave: MRSA; Prevention; Infection control; Latin America.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000800006
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Strategies to reduce mortality and morbidity due to AIDS-related cryptococcal meningitis in Latin America BJID
Vidal,Jose E.; Oliveira,Augusto C. Penalva de; Dauar,Rafi F.; Boulware,David R..
Latin America is the region with the third most AIDS-related cryptococcal meningitis infections globally. Highly active antiretroviral therapy (HAART) has reduced the number of infections; however, the number of deaths and the case-fatality rate continues to be unacceptable. In this review, we focus on the burden of AIDS-related cryptococcosis in Latin America and discuss potential strategies to reduce early mortality from Cryptococcus. In this review, we highlight the importance of: (1) earlier HIV diagnosis and HAART initiation with retention-in-care to avoid AIDS; (2) pre-HAART cryptococcal antigen (CRAG) screening with preemptive fluconazole treatment; (3) better diagnostics (e.g. CRAG testing); and (4) optimal treatment with aggressive management of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cryptococcal meningitis; Cryptococccosis; Epidemiology; Diagnosis; Treatment; Mortality; Latin America.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000300008
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Rates of antimicrobial resistance in latin america (2004-2007) and in vitro activity of the glycylcycline tigecycline and of other antibiotics BJID
Rossi,Flávia; García,Patricia; Ronzon,Bernardo; Curcio,Daniel; Dowzicky,Michael J.
As a part of the Tigecycline Evaluation and Surveillance Trial (T.E.S.T.), Gram-positive and Gram-negative bacterial isolates were collected from 33 centers in Latin America (centers in Argentina, Brazil, Chile, Colombia, Guatemala, Honduras, Jamaica, Mexico, Panama, Puerto Rico, and Venezuela) from January 2004 to September 2007. Argentina and Mexico were the greatest contributors of isolates to this study. Susceptibilities were determined according to Clinical Laboratory Standards Institute guidelines. Resistance levels were high for most key organisms across Latin America: 48.3% of Staphylococcus aureus isolates were methicillin-resistant while 21.4% of Acinetobacter spp. isolates were imipenem-resistant. Extended-spectrum β-lactamase were reported in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antibacterial resistance; Latin America; Tigecycline; Surveillance.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000500012
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The contribution of Latin American research to HPV epidemiology and natural history knowledge BJMBR
Sichero,L.; Picconi,M.A.; Villa,L.L..
Our aim was to review the major contributions of studies conducted in different Latin American (LA) countries to the field of human papillomavirus (HPV) epidemiology, natural history, risk of disease, and prevention strategies, mainly in the uterine cervix. Although cytological screening is established in several countries in LA, incidence and mortality rates from cervical cancer (CC) are still extremely high. Finally, data from large cohort studies conducted in LA countries provided seminal data to propose primary and secondary prevention modalities: the HPV vaccine has been introduced in the national immunization programs of several LA countries and multiple screening experiences using HPV testing are under evaluation in the region.
Tipo: Info:eu-repo/semantics/article Palavras-chave: HPV; Latin America; Immunization; Cervical cancer; Natural history; Screening.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2020000200302
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The importance of integrons for development and propagation of resistance in Shigella: the case of Latin America BJM
Barrantes,Kenia; Achí,Rosario.
Abstract In Latin America, the disease burden of shigellosis is found to coexist with the rapid and rampant spread of resistance to commonly used antibiotics. The molecular basis of antibiotic resistance lies within genetic elements such as plasmids, transposons, integrons, genomic islands, etc., which are found in the bacterial genome. Integrons are known to acquire, exchange, and express genes within gene cassettes and it is hypothesized that they play a significant role in the transmission of multidrug resistance genes in several Gram-negative bacteria including Shigella. A few studies have described antibiotic resistance genes and integrons among multidrug resistant Shigella isolates found in Latin America. For example, in Brazil, Bolivia, Chile, Costa...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Shigella; Antibiotic resistant; Integron; Gene cassettes; Latin America.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000400800
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Food security and livestock: The case of Latin America and the Caribbean Ciencia e Investigación Agraria
Rodríguez,Diego Ignacio; Anríquez,Gustavo; Riveros,José Luis.
The main hurdle to achieving food security in Latin America and the Caribbean is the inability of many poor families to access the foods necessary for a healthy diet, in a context in which food prices and family incomes are fundamental determinants. Animal husbandry plays a key role in the food security of the region, providing products rich in high-quality proteins and micronutrients and is vital for millions of households that depend on livestock for their livelihoods to generate income and have access to basic services. Furthermore, the production and trade of livestock products contributes to the stabilization of the food supply, acting as a buffer during economic crises and disasters both at the individual and community levels. Small farm agriculture...
Tipo: Journal article Palavras-chave: Food policies; Food security; Latin America; Livestock; Malnutrition; Rural livelihood; Small farm agriculture.
Ano: 2016 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202016000100001
Registros recuperados: 117
Primeira ... 123456 ... Última
 

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