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Martina Kutmon; Nicolas Rodriguez. |
The System Biology Format Converter (SBFC) aims is to provide a generic framework that potentially allows any conversion between two formats. Interoperability between formats is a recurring issue in Systems Biology. Although there are various tools available to convert models from one format to another, most of them have been independently developed and cannot easily be combined, specially to provide support for more formats. The framework is written in Java and can be used as a standalone executable. Recently a prototype has been developed with OSGi to achieve a more modular framework structure. This is a collaborative project and we hope that developers will provide support for more formats by creating new modules. SBFC allows anyone to easily add new... |
Tipo: Presentation |
Palavras-chave: Bioinformatics; Data Standards. |
Ano: 2011 |
URL: http://precedings.nature.com/documents/6370/version/1 |
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Boris Shmagin; Carol Johnston. |
Snow distribution in SD was studied with Factor Analysis (FA) of monthly total snowfall [in]. The long-term data obtained from the High Plains Regional Climate Center were used for the territory of South Dakota. The perspective for creating an Atlas of Climate and Water Resources for SD directed this study of total monthly snowfall with connection to landscape diversity.

The initial matrix {Xn*p} where n is number of stations and p is number of variables of monthly average for period of observations. The maximum number of stations n with mutual interval of observations for SD is equal 93 (n=93). These stations have mutual time interval of 18 years observations (1952-53 – 1969-70). Total monthly snowfall has... |
Tipo: Presentation |
Palavras-chave: Earth & Environment. |
Ano: 2008 |
URL: http://precedings.nature.com/documents/2445/version/1 |
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Mario Pineda-Krch; Richard Svanbäck; Michael Doebeli. |
Theoretical and empirical studies are showing evidence in support of evolutionary branching and sympatric speciation due to frequency‐dependent competition. However, phenotypic diversification due to underlying genetic diversification is only one possible evolutionary response to disruptive selection. Another potentially general response is phenotypic diversification in the form of phenotypic plasticity. It has been suggested that genetic variation is favored in stable environments, whereas phenotypic plasticity is favored in unstable and fluctuating environments. We investigate the “competition” between the processes of evolutionary branching and the evolution of phenotypic plasticity in a predator‐prey model... |
Tipo: Presentation |
Palavras-chave: Ecology; Evolutionary Biology. |
Ano: 2009 |
URL: http://precedings.nature.com/documents/3672/version/1 |
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Suzanne Savanick Hansen. |
Campus sustainability projects offer opportunities to link campus operations with academics. For ecologists, these links can include building upon urban long term ecological research such as urban nitrogen budgeting. In addition, the campus can serve as a tool to examine local biodiversity, urban storm water, and climate change issues in the classroom. This presentation will describe how an urban nitrogen budget at the University of Minnesota was developed. In addition, this presentation will describe how the Sustainability Office and the environmental studies department at Macalester College currently collaborate to develop campus sustainability academic projects. By linking to campus sustainability projects, ecologists have an opportunity to improve... |
Tipo: Presentation |
Palavras-chave: Earth & Environment. |
Ano: 2009 |
URL: http://precedings.nature.com/documents/4039/version/1 |
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Milind Watve; Maithili Jog. |
The parasite loads appear to differ widely within and between species of free ranging wild mammals. Using data on fecal propagule densities of 29 species of wild mammals from 20 wild life parks in India we tried to identify the ecological factors that are best predictors of parasite loads. Parasite loads were consistently negatively correlated with predatory pressures at both interspecific and intraspecific levels. Carnivores had higher mean parasite loads and the effect of diet and that of predatory pressure appeared to be independent of each other. No other ecological factors were significantly and consistently associated with fecal parasite loads. |
Tipo: Presentation |
Palavras-chave: Ecology. |
Ano: 2010 |
URL: http://precedings.nature.com/documents/4834/version/1 |
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Dharmendra Kumar Yadav; Feroz Khan; Arvind Singh Negi. |
Immuno-modulation is the process of alteration in immune response due to foreign intrusion of molecules inside the body. In the present communication QSAR and molecular docking studies for immuno-modulatory activity of derivatives of gallic acid were performed. Molecular docking studies showed higher binding affinity with INFα-2, IL-6, and IL-4 receptors. Binding site residues indicate hydrogen bonds formation with gallic acid derivative compounds G-3, G-4, G-5, G-6, G-7 and G-10. Further screening through quantitative structure activity relationship model establishes the immuno-modulatory activity of the compounds G-4, G-7, G-9, G-10, G-12 and G-13. Activity was predicted through a robust statistical model, developed by forward feed multiple... |
Tipo: Presentation |
Palavras-chave: Biotechnology; Cancer; Chemistry; Pharmacology; Bioinformatics; Plant Biology. |
Ano: 2011 |
URL: http://precedings.nature.com/documents/6620/version/1 |
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Lydie Lane. |
In September 2008, the UniProt/Swiss-Prot group achieved a major milestone: the first complete manual annotation of what is believed to be the full set of human proteins (derived from ~20'300 genes). This corpus of data is already quite rich in information pertinent to modern biomolecular medical research, but made us realize how large is the gap in our knowledge of human proteins in terms of functional information as well as protein characterization (PTMs, protein/protein interactions, subcellular locations, etc). This gap resides not only in the available experimental information, but also in the way this information has been stored, which is far from being sufficient to help researchers making sense of what all these human proteins do in our... |
Tipo: Presentation |
Palavras-chave: Bioinformatics; Data Standards. |
Ano: 2010 |
URL: http://precedings.nature.com/documents/5104/version/1 |
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Siddhartha S. Mukhopadhyay. |
The ever-growing application of clays in nanotechnology rests on fundamental principles of colloid chemistry. They make soils as nature’s great electrostatic chemical reactor. Highly anisotropic and often irregular particle shape, broad particle size distribution, different types of charges within the unit cells, heterogeneity of layer charges, pronounced CEC, dis-articulation and flexibility of layers, and different modes of aggregation make clays different from other colloidal materials. Their inseparable association with the genesis of life on Earth and evolutionary diversification of Neoproterozoic life is a safety-belt of nanotechnology. 

Nanotechnology promises to be the greatest technological... |
Tipo: Presentation |
Palavras-chave: Chemistry; Ecology; Earth & Environment. |
Ano: 2011 |
URL: http://precedings.nature.com/documents/5807/version/1 |
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Dragana Jovanovska; François Fages; Sylvain Soliman. |
BIOCHAM - BioChemical Abstract Machine is an environment for modeling biological systems and formalizing experimental knowledge. Mainly, it is composed of:
* a rule-based language for modeling biochemical systems (compatible with SBML)
* several simulators (boolean, differential, stochastic)
* a temporal logic based language to formalize the temporal properties of a biological system and validate models with respect to such specifications,
* unique features for developing/correcting/completing/reducing/coupling models, including the inference of kinetic parameters in high dimension from temporal logic constraints.

BIOCHAM is presented with a user... |
Tipo: Presentation |
Palavras-chave: Molecular Cell Biology; Bioinformatics. |
Ano: 2010 |
URL: http://precedings.nature.com/documents/5189/version/1 |
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Pinar Wennerberg; Sonja S. Zillner; Alexander Cavallaro. |
Formal knowledge about human anatomy, radiology or diseases is necessary to support clinical applications such as medical image search. This machine processable knowledge can be acquired from biomedical domain ontologies, which however, are typically very large and complex models. Thus, their straightforward incorporation into the software applications becomes difficult. In this paper we discuss first ideas on a statistical approach for modularizing large medical ontologies and we prioritize the practical applicability aspect. The underlying assumption is that the application relevant ontology fragments, i.e. modules, can be identified by the statistical analysis of the ontology concepts in the domain corpus. Accordingly, we argue that most frequently... |
Tipo: Presentation |
Palavras-chave: Bioinformatics. |
Ano: 2009 |
URL: http://precedings.nature.com/documents/3523/version/1 |
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Susanne Kögel; Jürgen Gross; Christoph Hoffmann. |
Introduced as a biological control agent in North America and middle Europe the Harlequin Ladybird _Harmonia axyridis_ has spread all over the countries and are capable to become an increasing problem for winegrowers and also households. Due to its preference to overwinter indoors _H. axyridis_ enters private homes and people may have allergic reactions to its odor or bites. During harvests, the beetles feed on grapes and may get crushed with them during processing causing release of hemolymph into the must. The hemolymph of ladybirds contains specific substances which consist mainly of pyrazines like the 3-isopropyl-2-methoxypyrazine. These chemical compounds are responsible for a specific alteration of the smell and taste of wine called... |
Tipo: Presentation |
Palavras-chave: Chemistry; Plant Biology. |
Ano: 2011 |
URL: http://precedings.nature.com/documents/5739/version/1 |
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Perumal P; Venkateswaralu B; D.N. Mohanty; Srinibas Das; Ashok Kumar Barik; P.C. Mishra. |
A pug aged 5 years was admitted in the Lyka pet clinic with difficulty in parturition. Breeding history of the dog was collected from the owner. X-ray was conducted which confirmed the presence of foetus. The bitch was manually handled to relieve the Dystocia following intravenous drip of N.S.S. and oxytocin. In the vent of unsuccessful attempt the bitch was surgically operated for C.S. and six fetuses of which four normal and two mummified were relieved. Routine post operative care were undertaken and the bitch recovered normally with out any complication. Photographic recording was also made during the recovery of mummified foetus. |
Tipo: Presentation |
Palavras-chave: Microbiology; Pharmacology. |
Ano: 2012 |
URL: http://precedings.nature.com/documents/7063/version/1 |
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Registros recuperados: 1.470 | |
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