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| Registros recuperados: 210 | |
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| Nicolas Le Novere; Emek Demir; Huaiyu Mi; Stuart Moodie; Alice Villeger. |
| Standard graphical representations have played a crucial role in science and engineering throughout the last century. Without electrical symbolism, it is very likely that our industrial society would not have evolved at the same pace. Similarly, specialised notations such as the Feynmann notation or the process flow diagrams did a lot for the adoption of concepts in their own fields. With the advent of Systems Biology, and more recently of Synthetic Biology, the need for precise and unambiguous descriptions of biochemical interactions has become more pressing. While some ideas have been advanced over the last decade, with a few detailed proposals, no actual community standard has emerged. The Systems Biology Graphical Notation (SBGN) is a graphical... |
| Tipo: Manuscript |
Palavras-chave: Bioinformatics; Data Standards. |
| Ano: 2011 |
URL: http://precedings.nature.com/documents/5902/version/1 |
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| Qi-Ren Zhang. |
| News shocked the physicist society that neutrinos may move faster than light. Most physicists affirm that this is impossible, according to the well-established relativity. Some try to find a new theory other than relativity to explain the phenomena. In the following we show it may be explained within relativity, if the quantum theory is also taken into account. |
| Tipo: Manuscript |
Palavras-chave: Data Standards. |
| Ano: 2012 |
URL: http://precedings.nature.com/documents/6887/version/1 |
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| S Bisai; R Khongsdier; K Bose; D Mahalanabis. |
| Malnutrition is an important public health problem worldwide. Therefore a study was undertaken to assess the prevalence of adolescent thinness, overweight and obesity in Midnapore town, West Bengal, India. A total of 974 adolescent boys aged 10-18 years were selected following multistage cluster sampling method from three higher secondary schools. Data was collected using pretested questionnaire following standard technique. Presence of thinness was evaluated using the cut-off values of international survey as suggested by Cole et al (2007). While overweight and obesity was determine by using international cut-off values develop by Cole et al (2000) based on international surveys as recommended by IOTF. Overall the prevalence of thinness, overweight and... |
| Tipo: Manuscript |
Palavras-chave: Developmental Biology; Ecology; Earth & Environment; Data Standards. |
| Ano: 2012 |
URL: http://precedings.nature.com/documents/7106/version/1 |
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| Julia Segre; Heidi Kong. |
| The Human Microbiome Project seeks to explore the diversity of microbiota that resides in and on the human body, including the skin, in health and disease. The NIH Intramural Skin Microbiome Consortium (NISMC) is a trans-disciplinary group of experts engaged in the practice of genomics, bioinformatics, large-scale DNA sequencing, dermatology, immunology, allergy, infectious disease, and clinical microbiology. Atopic dermatitis (AD, “eczema”) is a chronic relapsing skin disorder that affects ~15% of U.S. children and is associated with $1 billion of medical costs annually. AD is characterized by dry, itchy skin, infiltrated with immune cells. Colonization by _Staphylococcus aureus_ (_S. aureus_) is ten-fold more common in AD patients... |
| Tipo: Marker Paper / Data Plan |
Palavras-chave: Genetics & Genomics; Microbiology; Data Standards. |
| Ano: 2010 |
URL: http://precedings.nature.com/documents/5019/version/1 |
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| Mark Wilkinson; Benjamin Vandervalk; Luke McCarthy. |
| Background. 
The complexity and inter-related nature of biological data poses a difficult challenge for data and tool integration. There has been a proliferation of interoperability standards and projects over the past decade, none of which has been widely adopted by the bioinformatics community. Recent attempts have focused on the use of semantics to assist integration, and Semantic Web technologies are being welcomed by this community.

Description. 
SADI – Semantic Automated Discovery and Integration – is a lightweight set of fully standards-compliant Semantic Web service design patterns that simplify the publication of services of the type commonly found in... |
| Tipo: Manuscript |
Palavras-chave: Bioinformatics; Data Standards. |
| Ano: 2011 |
URL: http://precedings.nature.com/documents/6550/version/1 |
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| Anna Zhukova; Dagmar Waltemath; Nick Juty; Camille Laibe; Nicolas Le Novère. |
| To enable the accurate and repeatable execution of a computational simulation task, it is important to identify both the algorithm used and the initial setup. These minimum information requirements are described by the MIASE guidelines. Since the details of some algorithms are not always publicly available, and many are implemented only in a limited number of simulation tools, it is crucial to identify alternative algorithms with similar characteristics that may be used to provide comparable results in an equivalent simulation experiment. The Kinetic Simulation Algorithm Ontology (KiSAO) was developed to address this issue by describing existing algorithms and their inter-relationships through their characteristics and parameters. The use of KiSAO in... |
| Tipo: Presentation |
Palavras-chave: Bioinformatics; Data Standards. |
| Ano: 2011 |
URL: http://precedings.nature.com/documents/6330/version/1 |
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| David Shotton. |
| I propose five factors – peer review, open access, enriched content, available datasets and machine-readable metadata – as the Five Stars of Online Journal Articles, a constellation of five independent criteria within a multi-dimensional publishing universe against which online journal articles can be evaluated, to see how well they match up to current visions for research communications. Achievement along each of these publishing axes can vary, analogous to the different stars within the constellation shining with varying luminosities. I suggest a five-point scale for each by which a journal article can be evaluated, and a diagrammatic representation for such evaluations. While the criteria adopted for these scales are somewhat... |
| Tipo: Manuscript |
Palavras-chave: Data Standards. |
| Ano: 2011 |
URL: http://precedings.nature.com/documents/6542/version/1 |
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| Keisuke Ueno; Kouki Yonezawa; Katsuhiko Mineta; Toshinori Endo. |
| User annotation or comment interfaces are now widely used in several web sites such as journals, news, weblogs and Wikipedia. However, there are only a few biological databases with annotation interfaces. The _Ciona_ _intestinalis_ protein database (CIPRO) was created in order to provide integrated proteome data especially for experimental biologists. The current database contains 89,673 unique sequences covering all the known and predicted gene models. Typical tasks include which gene models are reliable and which function is plausible. The human-curated annotation is most important for the meaningful database.
Here we incorporate three new functions into the CIPRO2.5 database (http://cipro.ibio.jp/2.5/), providing enriched resources for... |
| Tipo: Presentation |
Palavras-chave: Bioinformatics; Data Standards. |
| Ano: 2010 |
URL: http://precedings.nature.com/documents/5064/version/1 |
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| Camille Laibe. |
| Quantitative models of biological systems provide an understanding of chemical and biological phenomena based on their underlying mechanisms. Moreover, they can be used for example, to predict the behaviour of a system under given conditions or direct future experiments. This has made quantitative models the perfect tools to answer a variety of questions in the biological sciences and has lead to a steady growth of the number of published models.

To maximise the benefits of this growing body of models, the field needs centralised model repositories that will encourage, facilitate and promote model dissemination and reuse. BioModels Database(http://www.ebi.ac.uk/biomodels/) has been developed to exactly fulfil those needs.... |
| Tipo: Presentation |
Palavras-chave: Bioinformatics; Data Standards. |
| Ano: 2012 |
URL: http://precedings.nature.com/documents/7013/version/1 |
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| Camille Laibe. |
| The MIRIAM Registry provides unique, perennial and location independent identifiers for data used in the biomedical domain. At its core is a shared catalogue of data collections, for each of which a unique namespace is created, and extensive metadata recorded. This namespace allows the generation of Uniform Resource Identifiers (URIs) to uniquely identify any record in a collection. We present here the new Identifiers.org service which is built upon the information stored in the Registry and which provides directly resolvable identifiers, in the form of Uniform Resource Locators (URLs). The flexibility of the identification scheme and resolving system allows its use in many different fields, where unambiguous and perennial identification of data entities... |
| Tipo: Presentation |
Palavras-chave: Data Standards. |
| Ano: 2011 |
URL: http://precedings.nature.com/documents/6479/version/1 |
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| Nicolas Rodriguez; Andreas Dräger. |
| The XML-based Systems Biology Markup Language (SBML) is the de facto standard file format for the storage and exchange of biochemical network models, and is supported by more than 180 software packages to date. Much of this success is due to SBML's clearly defined specifications and the availability of libSBML, a portable, robust and easy-to-use
library.
 
LibSBML provides many methods for manipulating and validating SBML files through its Application Programming Interface (API). Originally written in C and C++, libSBML also provides automatically-generated language bindings for Java, MATLAB, Perl, Python, and many more. However, the platform independence of Java is compromised in libSBML due to... |
| Tipo: Presentation |
Palavras-chave: Bioinformatics; Data Standards. |
| Ano: 2010 |
URL: http://precedings.nature.com/documents/4986/version/1 |
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| Registros recuperados: 210 | |
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