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One hundred million years of interhemispheric communication: the history of the corpus callosum BJMBR
Aboitiz,F.; Montiel,J..
Analysis of regional corpus callosum fiber composition reveals that callosal regions connecting primary and secondary sensory areas tend to have higher proportions of coarse-diameter, highly myelinated fibers than callosal regions connecting so-called higher-order areas. This suggests that in primary/secondary sensory areas there are strong timing constraints for interhemispheric communication, which may be related to the process of midline fusion of the two sensory hemifields across the hemispheres. We postulate that the evolutionary origin of the corpus callosum in placental mammals is related to the mechanism of midline fusion in the sensory cortices, which only in mammals receive a topographically organized representation of the sensory surfaces. The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Commissures; Evolution; Interhemispheric transfer; Lateralization; Synchronization.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000400002
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Critical steps in the early evolution of the isocortex: Insights from developmental biology BJMBR
Aboitiz,F.; Montiel,J.; López,J..
This article proposes a comprehensive view of the origin of the mammalian brain. We discuss i) from which region in the brain of a reptilian-like ancestor did the isocortex originate, and ii) the origin of the multilayered structure of the isocortex from a simple-layered structure like that observed in the cortex of present-day reptiles. Regarding question i there have been two alternative hypotheses, one suggesting that most or all the isocortex originated from the dorsal pallium, and the other suggesting that part of the isocortex originated from a ventral pallial component. The latter implies that a massive tangential migration of cells from the ventral pallium to the dorsal pallium takes place in isocortical development, something that has not been...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cdk5; Dorsal ventricular ridge; Reelin; Tangential migration; Ventral pallium.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002001200006
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