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Muscle Response to the Association of Statin and Physical Exercise in Rats International Journal of Morphology
Bonfim,Mariana Rotta; Camargo Filho,José Carlos Silva; Vanderlei,Luiz Carlos Marques; Padulla,Susimary Aparecida Trevizan; Accioly,Marilita Falângola; Souza,Dorotéia Rossi Silva; Azoubel,Reinaldo.
Physical exercise and statins, which are recommended for the treatment of dyslipidemia, are independently associated to the occurrence of muscle injury. The objective is analyze the effect of aerobic exercise associated to the use of simvastatin on the morphology of the gastrocnemius muscle. Thirty Wistar rats were divided into six groups, two of which received a standard diet (1 sedentary and 1 exercised) and four (1 sedentary with medication, 1 sedentary without medication, 1 exercised with medication, 1 exercised without medication) received a hypercholesterolemic diet (standard diet with the addition of cholesterol and coconut oil). Simvastatin (20 mg/Kg) was administered five days a week for eight weeks, together with aerobic training on a treadmill...
Tipo: Journal article Palavras-chave: Hydroxymethylglutaryl-CoA Reductase Inhibitors; Exercise; Skeletal Muscle.
Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000400031
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Effects of Passive Smoking Associated with Physical Exercise in the Skeletal Muscles of Rats During Pregnancy and Lactation International Journal of Morphology
Valsoni,Bruna Corral Garcia; Bonfim,Mariana Rotta; Camargo,Regina Celi Trindade; Abreu,Luiz Carlos de; Souza,Dorotéia Rossi Silva; Camargo Filho,José Carlos Silva.
The objective of this study was to analyze the effects of passive smoking, in soleus and gastrocnemius muscles associated with physical exercise by swimming during pregnancy and lactation of rats. Twenty-four rats were divided: GF (exposed to cigarette smoke), GC (control), GFN (underwent to the swimming program and exposed to cigarette smoke) and GN (underwent to the swimming program). On the first day of pregnancy procedure of exposure to cigarette smoke began, consisting in 30 minutes twice a day for six weeks. During the same period the swimming program began, which lasted 60 min every day untilthe 21st day of lactation. Soleus and gastrocnemius muscles, were obtained for histological, histochemical, morphometric analysis and fiber profiling. In...
Tipo: Journal article Palavras-chave: Passive Smoking; Physical Exercise; Pregnancy; Lactation; Skeletal Muscle.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000200015
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Effects of Statin and Aerobic Physical Exercise Association in the Cardiomyocytes of the Rat: Morphometric Study International Journal of Morphology
Padulla,Susimary Aparecida Trevizan; Azoubel,Reinaldo; Bonfim,Mariana Rotta; Accioly,Marilita Falángola; Camargo Filho,José Carlos Silva; Padovani,João Armando; Brandao,Antonio Carlos; Souza,Dorotéia Rossi Silva.
Physical exercise and statins, recommended interventions to dyslipidaemia treatment, are independently related to cardiomyocytes alterations, characterized by miocardic hypertrophy and apoptosis, respectively. Thus, the objective of the present study was to analyze the effects of statin and aerobic physical exercise association in the morphometric parameters of cardiac cell nucleus. 40 male rats adults were divided into four groups: exercised (DE); sedentary (DS), exercised and statin use (DES); sedentary and statin use (DSS). The animals received during the whole experimental period a hiperlipidic diet added 20% of coconut oil and 1.25% of cholesterol; after 30 days of its ingestión, a blood collection was made to verify the dyslipidaemia. Simvastatin (20...
Tipo: Journal article Palavras-chave: Hydroxymethylglutaryl-CoA Reductase Inhibitors; Exercise; Cardiomyocite nuclei.
Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000100015
Registros recuperados: 3
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