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	Provedor de dados ArchiMer (2) Autor Boudry, Gaelle (2) Falentin, Helene (1) Guernec, Gregory (1) Hamard, Alice (1) Jan, G (1) Le Cam, Aurelie (1) Le Floc'H, Nathalie (1) Le Huerou-luron, Isabelle (1) Loux, Valentin (1) Mazurais, David (1) Montfort, Jerome (1) Parayre, Sandrine (1) Saraoui, Taous (1) Seve, Bernard (1) Mais... Palavra-chave Gene expression (1) Paracellular permeability (1) Small intestine (1) Threonine (1) Tipo do documento Text (2) Ano 2013 (1) 2010 (1) País France (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última A unique in vivo experimental approach reveals metabolic adaptation of the probiotic Propionibacterium freudenreichii to the colon environment ArchiMer Saraoui, Taous; Parayre, Sandrine; Guernec, Gregory; Loux, Valentin; Montfort, Jerome; Le Cam, Aurelie; Boudry, Gaelle; Jan, G; Falentin, Helene. Background Propionibacterium freudenreichii is a food grade bacterium consumed both in cheeses and in probiotic preparations. Its promising probiotic potential, relying largely on the active release of beneficial metabolites within the gut as well as the expression of key surface proteins involved in immunomodulation, deserves to be explored more deeply. Adaptation to the colon environment is requisite for the active release of propionibacterial beneficial metabolites and constitutes a bottleneck for metabolic activity in vivo. Mechanisms allowing P. freudenreichii to adapt to digestive stresses have been only studied in vitro so far. Our aim was therefore to study P. freudenreichii metabolic adaptation to intra-colonic conditions in situ. Results We... Tipo: Text Ano: 2013 URL: http://archimer.ifremer.fr/doc/00171/28205/26433.pdf A moderate threonine deficiency affects gene expression profile, paracellular permeability and glucose absorption capacity in the ileum of piglets ArchiMer Hamard, Alice; Mazurais, David; Boudry, Gaelle; Le Huerou-luron, Isabelle; Seve, Bernard; Le Floc'H, Nathalie. High dietary threonine extraction by the digestive tract suggests that threonine contributes to maintain gut physiology. In the present study, we evaluated the impact of a low (6.5 g of threonine/kg diet; LT group) or a control well-balanced threonine diet (9.3 g of threonine/kg diet; C group) given to piglets for 2 weeks on ileal permeability and Na+-dependant glucose absorption capacity in Ussing chambers. The paracellular permeability was significantly increased in the ileum of LT compared to C piglets (P=.017). The Na+-dependent glucose absorption capacity showed a nonsignificant increase in the LT piglets. In addition, we analysed ileal gene expression profiles in the LT and C groups using porcine multitissue cDNA microarrays. Compared to the C... Tipo: Text Palavras-chave: Threonine; Small intestine; Paracellular permeability; Gene expression. Ano: 2010 URL: http://archimer.ifremer.fr/doc/00014/12531/9425.pdf Registros recuperados: 2 Primeira ... 1 ... Última

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