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Registros recuperados: 10 | |
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Betim,Fernando Cesar Martins; Oliveira,Camila Freitas de; Souza,Angela Maria de; Szabo,Ellis Marina; Zanin,Sandra Maria Warumby; Miguel,Obdulio Gomes; Miguel,Marilis Dallarmi; Dias,Josiane de Fátima Gaspari. |
The present study was undertaken to assess the potential uses of the essential oil obtained from Ocotea nutans (Nees) Mez. The hydrodistilled essential oil from O. nutans leaves was analyzed by gas chromatography-mass spectrometry. Fifty-eight compounds representing 87,29% of the total leaf essential oil components were identified, of which biciclogermacrene(11.41%), germacrene-D (4.89%), bisabolol-11-ol(3.73%) and spathulenol (3.71%) were the major compounds. The essential oil from O. nutans were tested for antibacterial activity using the minimum inhibitory concentracion (MIC) method, Artemia salina method, larvicidal activity in Aedes aegypti, and antioxidant capacity.The antioxidant activity measured by the phosphomolybdenum complex and Prussian blue... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ocoteanutans/essential oil/evaluation; Antioxidant capacity; Aedesaegypti; Toxic potential. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100513 |
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Nunes,Patrícia Mayra Pavan; Silva,Cristiane Bezerra da; Paula,Cristiane da Silva; Smolarek,Fernanda Ferreira; Zeviani,Walmes Marques; Chaves,Suelen Cristina; Lorini,Fernando; Dias,Josiane de Fátima Gaspari; Miguel,Obdulio Gomes; Zanin,Sandra Maria Warumby; Miguel,Marilis Dallarmi. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: < Italic> Citrus sinensis< /italic> (L.) Osbeck/residues/utilization < Italic> Citrus sinensis< /italic> (L.) Osbeck/seeds/allelopathic potential Rutaceae/residues/utilization Fixed oil Fatty acid. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000200479 |
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Fabri,Natasha Tiemi; Gatto,Larissa Junqueira; Furusho,Alethéia Santos; Garcia,Meira Janette Ballestros; Marques,Francisco de Assis; Miguel,Marilis Dallarmi; Montrucchio,Deise Prehs; Zanin,Sandra Maria Warumby; Miguel,Obdulio Gomes; Dias,Josiane de Fátima Gaspari. |
The article has aimed to characterize the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez. leaves, in terms of its chemical composition and antioxidant, hemolytic, and phytotoxic potentials, as well as its toxicity against Artemia salina. The major constituents identified by CG-MS were d-elemene, spathulenol, and b-atlantol. When screened for potential biological activities, the essential oil presented low toxicity against Artemia salina, and a capacity of lysing red blood cells. Also, the evaluation of its in vitro antioxidant activity, using the phosphomolybdenum method, showed better results when compared to butylhydroxytoluene (BHT) and rutin. In conclusion, the results obtained showed certain in vitro toxicity, leading to an interesting... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ocotea diospyrifolia; Lauraceae; Spathulenol; Antioxidant; Toxicity. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100593 |
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Cansian,Fernanda Colombi; Merino,Francis José Zortéa; Dias,Josiane de Fátima Gaspari; Zanin,Sandra Maria Warumby; Miguel,Obdulio Gomes; Miguel,Marilis Dallarmi. |
Species from the Bignoniaceae Family, including the genus Tynanthus, are very prevalent in the tropical Americas, with specimens found in a large part of the Brazilian territory. These plants are commonly used in traditional medicine for several purposes, and some studies have described their chemical structure, in addition to other reports related to some species from this genus. This review aimed to gather information from published works concerning species of the genus Tynanthus, as well as to detect flaws in research related to these plants, which may have great biological and pharmaceutical importance. Also, this review points out some common chemical characteristics of these species, providing information that may help new researchers to improve... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tynanthus/pharmacognosy; Tynanthus/phytochemistry; Tynanthus/biological activity; Bignoniaceae/pharmacognosy; Bignoniaceae/phytochemistry; Medicinal plants. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300515 |
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Fujiwara,Gislene Mari; Campos,Ranieri; Costa,Camila Klocker; Dias,Josiane de Fátima Gaspari; Miguel,Obdulio Gomes; Miguel,Marilis Dallarmi; Marques,Francisco de Assis; Zanin,Sandra Maria Warumby. |
Stigmasterol - a plant sterol with several pharmacological activities - is susceptible to oxidation when exposed to air, a process enhanced by heat and humidity. In this context, microencapsulation is a way of preventing oxidation, allowing stigmasterol to be incorporated into various pharmaceutical forms while increasing its absorption. Microparticles were obtained using a blend of polymers of sodium alginate, starch and chitosan as the coating material through a one-stage process using the external gelation technique. Resultant microparticles were spherical, averaging 1.4 mm in size. Encapsulation efficiency was 90.42% and method yield 94.87%. The amount of stigmasterol in the oil recovered from microparticles was 9.97 mg/g. This technique proved... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Stigmasterol/microencapsulation; Microencapsulation; Sodium alginate/drugs coating; Chitosan/drugs coating; Starch/drugs coating; Natural polymers/drugs coating. |
Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000300015 |
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Kalegari,Milena; Miguel,Marilis Dallarmi; Dias,Josiane de Fátima Gaspari; Lordello,Ana Luísa Lacava; Lima,Cristina Peitz de; Miyazaki,Cristina Mayumi Sasaki; Zanin,Sandra Maria Warumby; Verdam,Maria Christina dos Santos; Miguel,Obdulio Gomes. |
Most active plants are toxic at high doses and it is therefore important to investigate the preliminary toxicity of plant extracts. The Rourea induta species is a potential drug with no phytochemical or biological studies registered in the literature. Thus, a phytochemical study and a toxicity analysis of the ethanolic extract obtained from the leaves of Rourea induta Planch., Connaraceae, was run. A long chain hydrocarbon, n-tetracosane, and four flavonoids were identified: quercetin, and three glycosylated derivates, quercetin-3-O-α-arabinofuranoside, quercetin-3-O-β-xyloside and quercetin-3-O-β-galactoside. This is the first time these have been isolated in this species. The structures were elucidated by 13C NMR, ¹H NMR, UV and IR spectroscopy. The... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rourea induta/phytochemistry; Connaraceae/phytochemistry; Flavonoids; N-tetracosane; Plant extracts/toxicity. |
Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000300023 |
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Andrade,Cláudia Alexandra de; Carvalho,João Luiz de Souza; Cunico,Miriam Machado; Lordello,Ana Luísa Lacava; Higaskino,Carmen Etsuko Kataoka; Almeida,Siumara Costa da Cruz; Dias,Josiane de Fátima Gaspari; Kerber,Vitor Alberto; Miguel,Marilis Dallarmi; Miguel,Obdúlio Gomes. |
The extracts and fractions from the flowers of A. podalyriifolia were analyzed previously for antibacterial activity using diffusion in disk, Antioxidant properties were evaluated by determining radical scavenging power (DPPH test) and total phenol content was measured (Folin method). The present study describes the in vitro antibacterial (determining minimum inhibitory concentration) and antioxidant activities (by thiobarbituric acid reactive species - TBARS method) for the ethanol extract, dichloromethane and ethyl acetate fractions and two flavanones (naringenin and 5-β-D-glycosyl-naringenin) isolated from the flowers of Acacia podalyriifolia A. Cunn. ex G. Don. The flavanones naringenin and 5-β-D-glycosyl-naringenin had not previously been obtained... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acacia podalyriifolia/qualitative analysis; Acacia podalyriifolia/phytochemistry; Acacia podalyriifolia/antibacterial activity; Acacia podalyriifolia/antioxidant properties; Flavanones; 5-β-D-glycosyl-naringenin; Naringenin. |
Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000400013 |
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Merino,Francis José Zortéa; Ribas,Daniele Felipe; Silva,Cristiane Bezerra da; Duarte,Ana Flávia Schvabe; Paula,Cristiane da Silva; Oliveira,Maislian de; Dias,Josiane de Fátima Gaspari; Miguel,Marilis Dallarmi; Miguel,Obdulio Gomes. |
The objective of this study was to evaluate the effects of the ethanolic crude extracts and fractions of the species Senecio westermanii Dusén on Lactuca sativa L. (lettuce) and Allium cepa L. (onion) seeds. We assessed the germination, growth, root respiration and photosynthesis of the target species in Petri dishes (9.0 cm diameter) containing filter paper n°6. The study was conducted using 50 seeds per plate and held in 4 replicates per concentration of each sample. In the germination there was an inhibitory effect of fractions hexane (FH) and chloroform (FCl) at concentrations of 500 and 1000 µg/mL. There was a reduction in the radicle growth of lettuce by 14 to 24% and a reduction of hypocotilum by 14 to 28%. As for the radicle of the onion was up 74%... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Senecio westermanii/extract/effects; Lactuca sativa; Allium cepa; Allelochemicals; Allelopathy.. |
Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000300606 |
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Garcia,Carlos Eduardo Rocha; Bolognesi,Vinícius José; Dias,Josiane de Fátima Gaspari; Miguel,Obdúlio Gomes; Costa,Camila Klocker. |
A oxidação lipídica é uma das principais alterações que acometem os derivados cárneos em razão da composição química rica em lipídios e íons ferro, utilização de processos térmicos e de moagem, além do frequente uso do cloreto de sódio, um reconhecido catalisador desta reação. Os antioxidantes são substâncias utilizadas para inibir ou retardar a rancidez oxidativa, porém, seu uso desperta a atenção de consumidores e agências reguladoras, quanto à segurança que acompanha o consumo de aditivos sintéticos. Este trabalho teve por objetivo avaliar o uso dos carotenoides bixina e norbixina como antioxidantes em produtos cárneos por meio da revisão de suas características químicas, métodos de obtenção, toxicidade e aplicações tecnológicas. Esses pigmentos são... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Aditivo; Antioxidante natural; Carne; Corante; Pigmento; Rancidez; Oxidação. |
Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782012000800029 |
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Registros recuperados: 10 | |
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