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EFFECTS OF SODIUM CYCLAMATE IN KIDNEYS OF RATS FETUSES: A MORPHOMETRIC STUDY International Journal of Morphology
Ferraz de Arruda,José Germano; Tadeu Martins,Alex; Pereira Godoy,José Maria; Fácio Jr,Fernando Nestor; Azoubel,Reinaldo.
The cyclamate is used as artificial non-caloric sweetner in a wide variety of foods and beverages, being 30 times as sweet as sugar without the bitter after-taste of saccharin. It appears in the composition of the products as sodium and calcium cyclamates and cyclamic acid. The purpose of this research was to assess the effect of sodium cyclamate in kidneys of rats fetuses considering morphometric changes of glomerulus, proximal and distal convoluted tubules, and collecting duct. Ten pregnant rat (Rattus norvegicus) weighting an average of 238 g were divided into two groups: 5 in the control group and 5 in treated group with sodium cyclamate. Between the 10th and the 14th pregnancy day, 5 rats received an intraperitoneal daily injection of 60 mg/kg of body...
Tipo: Journal article Palavras-chave: Kidney; Sodium cyclamate; Morphometry; Experimental study.
Ano: 2004 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022004000200005
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