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	Provedor de dados BJMBR (2) J. Venom. Anim. Toxins (1) Autor Fernandes,I. (3) Macedo-Soares,M.F. (2) Oshiro,T.M. (2) Enobe,C.S. (1) Itami,D.M. (1) Pires,R.R. (1) Rafael,A. (1) Mais... Palavra-chave Ascaris suum (2) Allergen (1) IgE (1) Immunomodulation (1) Immunosuppression (1) Monoclonal antibodies (1) Monoclonal antibody (1) Mais... Tipo do documento Info:eu-repo/semantics/other (3) Ano 2004 (1) 2001 (1) 1997 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última NEUTRALIZING ABILITY OF IgG(T) AND IgGa ISOTYPES PRESENT IN HORSE HYPERIMMUNE SERUM AGAINST SNAKE VENOM J. Venom. Anim. Toxins Fernandes,I.. Tipo: Info:eu-repo/semantics/other Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301997000100009 Production and characterization of a monoclonal antibody against an Ascaris suum allergenic component BJMBR Pires,R.R.; Oshiro,T.M.; Itami,D.M.; Fernandes,I.; Macedo-Soares,M.F.. Ascaris suum allergenic components (PIII) separated by gel filtration chromatography of an adult worm extract were used to immunize BALB/c mice. Popliteal lymph node cells taken from the immunized animals were fused with SP2/O myeloma cells using polyethylene glycol (MW 1450) as fusogen. The hybridomas were cultured in HAT-containing medium and cloned at limiting dilutions. Supernatants from the growing hybrids were screened by ELISA using plates coated with PIII or the A. suum crude extract. The monoclonal antibody obtained, named MAC-3 (mouse anti-A. suum allergenic component), is an IgG1 kappa mouse immunoglobulin that specifically recognizes a 29,000 molecular weight protein (called allergenic protein) with an affinity constant of 1.7 x 10(9) M-1. The... Tipo: Info:eu-repo/semantics/other Palavras-chave: Ascaris suum; Allergen; IgE; Monoclonal antibodies. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000800009 Comparison of different monoclonal antibodies against immunosuppressive proteins of Ascaris suum BJMBR Oshiro,T.M.; Rafael,A.; Enobe,C.S.; Fernandes,I.; Macedo-Soares,M.F.. The extract of Ascaris suum suppresses the humoral and cellular immune responses to unrelated antigens in the mouse. In order to further characterize the suppressive components of A. suum, we produced specific monoclonal antibodies which can provide an important tool for the identification of these proteins. The A. suum immunosuppressive fractions isolated by gel filtration from an extract of adult worms were used to immunize BALB/c mice. Popliteal lymph node cells taken from the immunized animals were fused with SP2/O myeloma cells and the cloned hybrid cells obtained were screened to determine the specificity of secreted antibodies. Three monoclonal antibodies named MAIP-1, MAIP-2 and MAIP-3 were selected and were shown to react with different epitopes... Tipo: Info:eu-repo/semantics/other Palavras-chave: Ascaris suum; Immunosuppression; Immunomodulation; Monoclonal antibody. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000200009 Registros recuperados: 3 Primeira ... 1 ... Última

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