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	Provedor de dados BJMBR (2) Autor Fuxe,K. (2) Chadi,G. (1) Fior-Chadi,D.R. (1) Palavra-chave Alpha-2-adrenoceptors (1) Angiotensin II receptors (1) Astrocyte (1) Basic fibroblast growth factor (1) Brain lesion (1) Central nervous system (1) FGF receptor (1) Image analysis (1) In situ hybridization (1) Neuropeptide Y receptors (1) Nucleus tractus solitarii (1) Quantitative radioautography (1) Radioautography (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 1998 (2) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Analysis of trophic responses in lesioned brain: focus on basic fibroblast growth factor mechanisms BJMBR Chadi,G.; Fuxe,K.. The actions of fibroblast growth factors (FGFs), particularly the basic form (bFGF), have been described in a large number of cells and include mitogenicity, angiogenicity and wound repair. The present review discusses the presence of the bFGF protein and messenger RNA as well as the presence of the FGF receptor messenger RNA in the rodent brain by means of semiquantitative radioactive in situ hybridization in combination with immunohistochemistry. Chemical and mechanical injuries to the brain trigger a reduction in neurotransmitter synthesis and neuronal death which are accompanied by astroglial reaction. The altered synthesis of bFGF following brain lesions or stimulation was analyzed. Lesions of the central nervous system trigger bFGF gene expression by... Tipo: Info:eu-repo/semantics/article Palavras-chave: Radioautography; In situ hybridization; Basic fibroblast growth factor; FGF receptor; Astrocyte; Image analysis; Central nervous system; Brain lesion. Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000200007 Quantitative receptor radioautography in the study of receptor-receptor interactions in the nucleus tractus solitarii BJMBR Fior-Chadi,D.R.; Fuxe,K.. The nucleus tractus solitarii (NTS) in the dorsomedial medulla comprises a wide range of neuropeptides and biogenic amines. Several of them are related to mechanisms of central blood pressure control. Angiotensin II (Ang II), neuropeptide Y (NPY) and noradrenaline (NA) are found in the NTS cells, as well as their receptors. Based on this observation we have evaluated the modulatory effect of these peptide receptors on <FONT FACE="Symbol">a</font>2-adrenoceptors in the NTS. Using quantitative receptor radioautography, we observed that NPY and Ang II receptors decreased the affinity of <FONT FACE="Symbol">a</font>2-adrenoceptors for their agonists in the NTS of the rat. Cardiovascular experiments agreed with the in vitro data.... Tipo: Info:eu-repo/semantics/article Palavras-chave: Quantitative radioautography; Nucleus tractus solitarii; Alpha-2-adrenoceptors; Neuropeptide Y receptors; Angiotensin II receptors. Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000200006 Registros recuperados: 2 Primeira ... 1 ... Última

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