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Effects of Preweaning Polysensorial Enrichment upon Development of the Parietal Cortical Plate of Undernourished Rats: A Stereological Study International Journal of Morphology
González,Héctor; Adaro,Luis; Hernández,Alejandro; Fernández,Víctor.
This investigation was undertaken in order to quantify the effects of early polysensorial enrichment on the development of cortical pyramids, located in the parietal cortex of rats simultaneously submitted to protein-energy undernutrition. A short period of stimulation during suckling significantly decreases the cellular density in the cortical plate (phylogenetic-ontogenetic evolutionary index). Results suggest that the cerebral cortex develops according to a sophisticated neuronal network, which exhibits a notable degree of structural specificity, regulated by genetic and environmental clues. The most obvious prediction is that environmental influences are probably transduced as a structural expression in the developing parietal cortical plate.
Tipo: Journal article Palavras-chave: Environmental enrichment; Cortical gradients; Undernutrition; Parietal cortex; Stereology.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000400016
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Anatomy of corpus callosum in prenatally malnourished rats Biol. Res.
Olivares,Ricardo; Morgan,Carlos; Pérez,Hernán; Hernández,Alejandro; Aboitiz,Francisco; Soto-Moyano,Rubén; Gil,Julio; Ortiz,Alexis; Flores,Osvaldo; Gimeno,Miguel; Laborda,Jesús.
The effect of prenatal malnutrition on the anatomy of the corpus callosum was assessed in adult rats (45-52 days old). In the prenatally malnourished animals we observed a significant reduction of the corpus callosum total area, partial areas, and perimeter, as compared with normal animals. In addition, the splenium of corpus callosum (posterior fifth) showed a significant decrease of fiber diameters in the myelinated fibers without changing density. There was also a significant decrease in diameter and a significant increase in density of unmyelinated fibers. Measurements of perimeter's fractal dimensions from sagittal sections of the brain and corpus callosum did not show significant differences between malnourished and control animals. These findings...
Tipo: Journal article Palavras-chave: Corpus callosum; Prenatal malnutrition; Rat; Splenium.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000100012
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