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| Registros recuperados: 16 | |
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| Albuquerque,Sergio de; Lopes,Ruberval Armando; Sala,Miguel Angel; Abraháo,Ana Amelia Carraro; Ribeiro,Rosa Domingues. |
| Fueron estudiadas las alteraciones y el nivel de deterioro de las parótidas de animales infectados con la cepa RAL de Trypanosoma cruzi. Se utilizaron ratones albinos (Mus musculus) de ambos sexos, debido al dimorfismo sexual de las glándulas salivares, inoculados con 2 x 10(4) tripomastigotes sanguíneos de la cepa RAL del T. cruzi. Los animales fueron sacrificados al 12° día de infección, coincidiendo con el pico parasitémico. La parótida fue procesada histológicamente y, posteriormente, evaluada histopatológica y morfometricamente. Los resultados permitieron verificar intenso parasitismo en la glándula, la que presentó desorganización estructural y atrofia generalizada de acinos y conductos, más intensos en las hembras. Concluyendo, la cepa RAL del T.... |
| Tipo: Journal article |
Palavras-chave: Trypanosoma cruzi; Cepa RAL; Ratón; Parótida; Histopatología; Morfometría. |
| Ano: 2007 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000200004 |
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| Martins,Alex Tadeu; Santos,Fabiano de Sant´Ana dos; Scannavino,Fábio Luiz Ferreira; Pires,Juliana Rico; Zuza,Elizângela Partata; Junior,João Armando Padovani; Azoubel,Reinaldo; Di Mateo,Miguel Angel Sala; Lopes,Ruberval Armando. |
| The cyclamate, a sweetner substance derived from N-cyclo-hexyl-sulfamic acid, is largely utilized as a non-caloric artificial edulcorant in foods and beverages as well as in the pharmaceutical industry. The objective of this study was to evaluate karyometric and stereological alterations in the rat fetal pancreas resulting from the intraperitoneal administration of sodium cyclamate. The exocrine pancreas of ten fetuses of rats were evaluated, five treated and five controls chosen at random, in which five rats that received from the 10th to 14th days of pregnancy an intraperitoneal daily injection of sodium cyclamate at 60 mg/Kg of body weight during 5 days. At the 20th day of gestation, the animals were removed and weighed, as were their placentas; the... |
| Tipo: Journal article |
Palavras-chave: Sodium cyclamate; Exocrine pancreas; Karyometry; Stereology. |
| Ano: 2010 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000300038 |
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| Kassis,Elias Nairn; Azoubel,Reinaldo; Lopes,Ruberval Armando; Martins,Alex Tadeu; Matteo,Miguel Ángel Sala di; Gawlinski,Viviane Curi. |
| The present work studied the adverse effects of maternal exposure of rats to alcohol during lactation, on the development of their offspring. Histometric evaluation by karyometry and of the palatine epithelium of the sucking was performed. Two groups of animals, one coming from mothers exposed to drinking water containing 20% ethanol during the total lactation period and the other of controls coming from mothers receiving only alcohol-free drinking water during this period. On the 21 first day of lactation the young of each group were aleatorily selected and following anesthesia, their heads severed; after histological treatment, serial 6 |J,m sections on the frontal plane at the molar level, stained with hematoxilin and eosin, were obtained. The... |
| Tipo: Journal article |
Palavras-chave: Ethanol; Palatine epithelium; Lactation. |
| Ano: 2007 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000400013 |
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| Issa,João Paulo Mardegan; Tiossi,Rodrigo; Watanabe,Plauto Christopher Aranha; Siéssere,Selma; Regalo,Simone Cecílio Hallak; Lopes,Ruberval Armando; Di Matteo,Miguel Angel Sala; Iyomasa,Mamie Mizusaki; Defino,Helton Luiz Aparecido. |
| The purpose of this study was to evaluate the newly formed bone, comparing two different carriers for rhBMP-2, using the decortication and nondecorticatication surgical technique in Wistar rat mandibles, evaluated by radiographic densitometry method. It was used fifty six animals according to specific treatment, which were sacrificed after 3 and 6 weeks after this. It was concluded that the decortication surgical technique was able to optimize the osteoinduction properties of the rhBMP-2, independently of the material carrier used and the period of time, according to radiographic densitometry technique. |
| Tipo: Journal article |
Palavras-chave: Radiography; Densitometry; Mandible; RhBMP-2; Bone. |
| Ano: 2008 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000100014 |
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| Felippini,Ana Luiza de Carvalho; Sala,Miguel Angel; Lopes,Ruberval Armando; Silva,Gilberto André e. |
| The purpose of this study was to evaluate the effects of zinc, during lactation, on the junctional epithelium and inserted gum of the first upper molar of rats. The study used one-day old male rats, divided into two groups: those whose mother had been treated with 300 mg zinc chloride (ZnCl2) in the drinker water (treated group), and those whose mothers did not receive ZnCl2 (control group). After 21 days, the rat pups were sacrificed. Using karyometrical techniques, the greater (D) and smaller (d) nuclear diameters of the different layers of the junctional and inserted gum epithelia were determined, and the mean geometric diameter, D/d ratio, perimeter, area, volume, volume/area ratio, eccentricity, shape coefficient, and the contour index were estimated.... |
| Tipo: Journal article |
Palavras-chave: Zinc; Lactation; Junctional epithelium; Inserted gum. |
| Ano: 2013 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000100024 |
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| Issa,Joao Paulo Mardegan; Petenusci,Sergio Olavo; Siéssere,Selma; Regalo,Simone Cecilio Hallak; Lopes,Ruberval Armando; Di Matteo,Miguel Ángel Sala; Iyomasa,Mamie Mizusaki; Defino,Helton Luiz Aparecido. |
| The aim of this study was to evaluate the calcium dosage of the newly formed bone, in critical bone defects created on the calvarial tissue and filled by different substances, in male Wistar rats. A cylindrical critical bone defect (6x2mm) was created in the posterior portion, left side, on the calvarial bone in nine animals and filled with: animals' coagulum, monoolein gel, poloxamer gel, monoolein gel + 1µg rhBMP-2, monoolein gel + 3µg rhBMP-2, monoolein gel + 7µg rhBMP-2, poloxamer gel + 1µg rhBMP-2, poloxamer gel + 3µg rhBMP-2, poloxamer gel + 7µg rhBMP-2. The results of this study showed a positive correlation between the calcium dosage analysis and the newly formed bone |
| Tipo: Journal article |
Palavras-chave: Bone repair; Biomaterials; RhBMP-2; Carriers; Calcium. |
| Ano: 2007 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000300006 |
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| Felippini,Ana Luiza de C; Lopes,Ruberval Armando; Sala,Miguel Angel; Watanabe,Ii-Sei; Lopes,Túlio Roberto V.P; Issa,João Paulo M; Ribas,José Paulo. |
| El cobalto es uno de los principales componentes de las aleaciones metálicas fundidas, usadas frecuentemente en odontología. El metal es el constituyente de 45 a 70% de los trabajos protéticos. En virtud de la existencia de evidencias que elementos metálicos pueden causar toxicidad sistémica y local, este trabajo tuvo como objetivo evaluar los efectos del cobalto sobre el epitelio de unión y el epitelio del esmalte del primer molar superior de rata, durante la lactancia. Con esa finalidad fueron usadas ratas con 1 día de vida postnatal, cuyas madres recibieron 300 mg de cloruro de cobalto por litro de agua destilada en el bebedero, durante a la lactancia. Al cabo de 21 días, las crías fueron sacrificadas con sobredosis anestésica. Las cabezas fueron... |
| Tipo: Journal article |
Palavras-chave: Cobalto; Rata; Lactancia; Epitelio de Unión; Epitelio Reducido del Esmalte. |
| Ano: 2009 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000400021 |
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| Carrara Moreti,Dora Lúcia; Lopes,Ruberval Armando; Vinha,Dionisio; Sala,Miguel Angel; Semprini,Marisa; Friedrichi,Christiane. |
| El objetivo del presente trabajo fue caracterizar morfológica, morfométrica y estereológicamente las alteraciones causadas por la administración de albendazol en ratas preñadas en el hígado de los fetos. Fueron usadas ratas Wistar, que recibieron entre los días 9 y 11 de la preñez, una dosis diaria de 5 mg/kg de peso de albendazol. Las ratas control recibieron volumen semejante de suero fisiológico en los mismos días. Al 20 día, las ratas fueron sacrificadas por inhalación de éter, siendo retirados los fetos e inmediatamente fijados en alfac por 24 h. Los fetos, úteros y placentas, luego de fijados, fueron secados en papel de filtro y pesados en balanza de precisión, siendo medidos los cordones umbilicales con nonio. Los cuerpos de los fetos fueron... |
| Tipo: Journal article |
Palavras-chave: Hígado; Feto; Rata; Albendazol; Morfometría. |
| Ano: 2005 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022005000200003 |
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| Curi,Viviane; Azoubel,Reinaldo; Lopes,Ruberval Armando; Martins,Alex Tadeu; Sala Di Matteo,Miguel Ángel; Kassis,Elias Naim. |
| The present work studied the adverse effects of maternal exposure of rats to alcohol during lactation, on the development of their off spring. Histometric evaluation by karyometry and of the alveolar bone at the level of the first upper molar of the sucking was perfomed. Two groups of animáis, one coming from mothers exposed to drinking water containing 20% ethanol during the total lactation period and the other of controls coming from mothers receiving only alcohol-free drinking water during this period. On the 21 first day of lactation the young of each group were aleatorily selected and following anesthesia, their heads severed; after histological treatment, serial 6 μm sections on the frontal plañe at the molar level, stained with hematoxilin... |
| Tipo: Journal article |
Palavras-chave: Ethanol; Alveolar bone; Lactation. |
| Ano: 2008 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000400026 |
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| Lara,Cristina Picoli; Watanabe,Ii-Sei; Lopes,Ruberval Armando; Sala,Miguel Angel; Picoli,Fábio. |
| El cadmio del aire, agua y alimentos tiene potencial de afectar la salud de las personas, principalmente de aquellas que viven en regiones industrializadas. El cadmio afecta la función placentaria, pudiendo atravesar la barrera trofoblástica y provocar alteraciones en el desarrollo del feto; puede, también, ser excretado por la leche. El organismo es particularmente susceptible a la exposición al cadmio en el periodo perinatal. Se estudió el efecto de la intoxicación por cadmio en el epitelio vestibular y suelo de la boca de ratas expuestas a niveles bajos de cadmio en el agua del bebedero, durante la lactancia. Las ratas recibieron agua ad libitum conteniendo 300 mg/l de CdCl2 durante los 21 días de lactancia. Los animales controles recibieron un volumen... |
| Tipo: Journal article |
Palavras-chave: Mucosa oral; Cadmio; Lactancia; Rata; Histopatología; Morfometría. |
| Ano: 2003 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022003000300002 |
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| Aparecida Marinho,Sandra; Sala,Miguel Angel; Lopes,Ruberval Armando; de Moraes Grisi,Márcio Fernando; Belém Novaes Jr.,Arthur; Scombatti de Souza,Sérgio Luis; Taba Jr.,Mário. |
| SUMMARY: The effects of acetylsalicylic acid (ASA) on intrauterine growth restriction induced by maternal ethanol consumption were studied. A single intraperitoneal dose of ethanol (2.96 g/kg body weight), injected on the 10th day of pregnancy (PD10), significantly reduced maternal weight gain, fetal weight, amniotic fluid volume and umbilical cord length. Meanwhile, ethanol did not affect placental weight or litter size. A single intraperitoneal dose of ASA (200 mg/g body weight), injected on the PD10, did not modify maternal body weight gain, litter size, fetal and placental weights and amniotic fluid volume, but significantly diminished umbilical cord length. Intraperitoneal injections of either ASA (200 mg/g body weight) or ethanol (2.96 g/kg body... |
| Tipo: Journal article |
Palavras-chave: Rat; Fetus; ASA; Ethanol; Intrauterine development. |
| Ano: 2003 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022003000200002 |
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| Friedrichi,Christiane; Lopes,Ruberval Armando; Sala,Miguel Angel; Felippini,Ana Luiza de C; Issa,João Paulo M; Watanabe,Ii-Sei; Lopes,Túlio Roberto V. P. |
| El cadmio (Cd), presente en el aire, agua potable y alimentos, tiene potencial para afectar la salud humana, principalmente en las regiones altamente industrializadas. El Cd además de afectar la función placentaria, puede atravesar la barrera placentaria y perjudicar directamente el desarrollo fetal. En virtud de que el organismo es particularmente susceptible a la exposición al Cd durante el período perinatal, y que ese metal puede ser excretado en la leche, el objetivo del presente trabajo fue estudiar los efectos de la exposición continua a agua potable conteniendo bajos niveles de Cd durante la lactancia sobre las glándulas salivales de la rata. Ratas hembra recibieron agua potable conteniendo 300mg/l de CdCl2 ad libitum durante toda la lactancia.... |
| Tipo: Journal article |
Palavras-chave: Cadmio; Rata; Lactancia; Glándulas salivales; Histometría. |
| Ano: 2009 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000400028 |
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| Sala,Miguel Ángel; Lopes,Ruberval Armando; Abrahão,Ana Amelia Carraro; Meneguette,Cicero; Albuquerque,Sérgio de; Ribeiro,Rosa Domingues. |
| El objetivo de este trabajo fue evaluar cariometricamente las alteraciones causadas por diferentes cepas de T. cruzi en la placenta del ratón. Ratones hembras de 60 días, grávidas, fueron inoculadas, intraperitonealmente, con 2 x 10(5) tripomastigotes sanguíneos de las cepas colombiana, Y, Solivia o RC del T. cruzi. Fueron observadas claras diferencias en las alteraciones cariométricas de las células trofoblásticas gigantes y de las células trofoblásticas de la zona esponjosa. Los resultados demostraron que las cepas colombiana y RC causan alteraciones tanto en las células trofoblásticas gigantes como en las células del trofoblasto esponjoso, mientras que las cepas Y y Bolivia provocan alteraciones solamente en las células trofoblásticas gigantes. Es... |
| Tipo: Journal article |
Palavras-chave: Enfermedad de Chagas Experimental; Trypanosoma cruzi; Ratón; Placenta; Cariometría. |
| Ano: 2008 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000300018 |
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| Motta,Ana Carolina Fragoso; Migliari,Dante Antonio; Gioso,Marco Antonio; Komesu,Marilena Chinali; Sala,Miguel Angel; Lopes,Ruberval Armando. |
| Cadmium (Cd) is a heavy metal that exerts a variety of toxic effects, chronic and acute, in exposed organisms. The aim of this study was to investigate the carcinogenic potential of Cd in the palatal and gingival epithelium of Wistar rats. Two groups of animals were studied: group 1 consisted of 5 rats exposed to cadmium chloride (CdCl2) in drinking water (300 mg/L) for 6 months; group 2 also consisted of 5 rats placed in the same conditions as those of group 1, but kept free of Cd for 6 additional months. Two other groups (C1 and C2) with the same number of animals, but not exposed to CdCl2, were used as a control for groups 1 and 2, respectively. All animals were weighed before and after the experimental period. After animals being killed, tissues of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cadmium chloride; Ooral cancer; Carcinogenesis; Rat. |
| Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-95962004000300006 |
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| Registros recuperados: 16 | |
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