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| TOMIHARI, Mizuki; NISHIHARA, Akira; SHIMADA, Terumasa; YANAGAWA, Masashi; MIYOSHI, Masafumi; MIYAHARA, Kazurou; OISHI, Akihiro; 富張, 瑞樹; 宮原, 和郎; 大西, 明弘. |
| Most anesthetics have an immuno-suppressive effect on cellular and neurohumoral immunity, and research shows that total intravenous anesthesia (TIVA) with propofol has a greater immuno-protective effect than inhalational anesthesia in human medicine. However, in veterinary clinics, these effects remain ambiguous. To clarify the details, we focused on propofol and isoflurane, investigating clinical blood hematology and immunological profiles drawn from healthy dogs under and after two anesthesia techniques. Twelve healthy adult beagles were included in this study, randomly assigned to the propofol anesthesia group (group P: n=6) or the isoflurane anesthesia group (group I: n=6). In both groups, the number of lymphocytes in peripheral blood decreased after 2... |
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Palavras-chave: Anesthesia; Canine; Immuno-suppression; Isoflurane; Propofol. |
| Ano: 2015 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4209 |
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| 佐藤, 巌紀; 西村, 麻紀; 三好, 雅史; 川本, 恵子; 古林, 与志安; 磯村, 洋; 宮原, 和郎; SATO, Genki; NISHIMURA, Maki; MIYOSHI, Masahumi; KAWAMOTO, Keiko; KOBAYASHI, Yoshiyasu; ISOMURA, Hiroshi; MIYAHARA, Kazurou. |
| 下唇の腫脹と下顎リンパ節の腫脹を伴った1 2 歳のT 細胞型皮膚型リンパ腫のシーズー犬に対してロムスチン （CCNU）による治療を行ったが効果は認められなかった．そこで，1回4Gyを2日おきに計5回，総線量20Gyで放射 線治療を実施したところ，腫脹の軽減が認められた．その後，飼い主希望により，積極的な治療は行わなかったが，数 回の放射線治療のたびに，改善が認められた．最終的に下唇と下顎リンパ節の腫瘤が増大し，第234 病日に斃死した．We administered lomustine (CCNU) to a 12-year-old Shih Tzu with T-cell type cutaneous lymphoma with swelling of the lower lip and mandibular lymph node. The treatment was ineffective and there was no reduction in the swelling in either area. Next, we carried out five radiation treatments (4Gy once every two days) with a total dose of radioactivity of 20Gy. Following the wishes of the owner, we did not perform further treatment. However, after several radiation treatments, there was a noticeable reduction in the swelling of the lower lip and... |
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Palavras-chave: 皮膚型リンパ腫; ロムスチン（CCNU）; 放射線治療; Cutaneous lymphoma; Lomustine (CCNU); Radiationtherapy. |
| Ano: 2010 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2940 |
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