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| Malheiros,Camila Krüger Cardoso; Silva,Joyce Sayonara Barbosa; Hofmann,Tânia Cristiane; Messina,Thiane Martins; Manfredini,Vanusa; Piccoli,Jacqueline da Costa Escobar; Faoro,Débora; Oliveira,Luís Flávio Souza; Machado,Michel Mansur; Farias,Fabiane Moreira. |
| ABSTRACT The bark tea of Ceiba speciosa, a tropical tree of the Malvaceae family, is used in the Northwestern Region of Rio Grande do Sul state, Brazil, to reduce blood cholesterol levels. However, there are no scientific data on the efficacy and safety of this plant. The aim of the present study was to evaluate the in vitro antioxidant and toxic potential of bark extracts of C. speciosa. We performed a preliminary phytochemical analysis by high-performance liquid chromatography-diode array detection (HPLC-DAD) and evaluated the oxidative damage to proteins and lipids, the radical scavenging effect, and genotoxicity of the lyophilized aqueous extract (LAECs) and the precipitate obtained from the raw ethanol extract (Cs1). The phytochemical profile... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ceiba speciose/phytochemistry; Ceiba speciose/antioxidant activity; Phenolic content; Comet assay; DPPH scavenging capacity; Natural medicine; Safety. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000200616 |
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| Prichoa,Franciele Carla; Roman,Silvane Souza; Manfredini,Vanusa. |
| The use of plant species is emerging as an important alternative in the treatment of injuries. Therefore, the extract of Sonchus oleraceus 10% was employed in the repair of skin lesions. A total of 36 male Wistar rats were subjected to a punch injury and divided into three groups: a negative control, receiving no treatment, a positive control, treated with Dersani, and the experimental group treated with the extract. The injury was assessed macroscopically and microscopically. Morphometric data was collected at the 3rd, 5th and 7th postoperative day, and the experimental group showed greater changes in shrinkage of the lesion compared to control groups. On the 3rd postoperative day, the injury in the experimental group showed less necrotic tissue, lower... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sonchus oleraceus/pharmacognosy; Skin lesions/treatment; Skin lesions/experimental study; Wound healing/experimental study; Medicinal plants. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000300019 |
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