|
|
| Lira,S.M.; Canabrava,N.V.; Benjamin,S.R.; Silva,J.Y.G.; Viana,D.A.; Lima,C.L.S.; Paredes,P.F.M.; Marques,M.M.M.; Pereira,E.O.; Queiroz,E.A.M.; Guedes,M.I.F.. |
| Diabetes mellitus is one of the most common chronic degenerative diseases, and it is estimated to increase worldwide to around 415 million and to impact 642 million in 2040. Research shows that some plants are sources of bioactive compounds against diabetes. Thus, the objective of this work was to evaluate the oral toxicity and the hypoglycemic effect of the aqueous extract of the leaves of Cnidoscolus quercifolius Pohl. Diabetes was induced in Swiss mice with streptozotocin and the mice were treated with an aqueous extract of C. quercifolius leaves for a period of 30 days. Phytochemical analysis showed that the extract was rich in flavonoids, catechins and triterpenoid, which did not show any mortality and behavioral alterations in mice treated with 200,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Faveleira; Diabetes mellitus; Medicinal plants; Hypoglycemic activity; Aqueous extracts. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017001000612 |
| |
