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Registros recuperados: 24 | |
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Manterola,Carlos; Otzen,Tamara. |
Splenectomy indications are hematologic disease, traumatic damage and iatrogenic injury. The aim of this study was to present an evidence-based overview of some clinical aspects of interest related with iatrogenic splenic injury and subsequent splenectomy. An overview of the available evidence was conducted. Articles that evaluated clinical aspects of interest related with iatrogenic splenic injury and subsequent splenectomy, without language limits, publication date and designs. BVS, PubMed, SciELO and TRIP databases were reviewed. Evaluated variables were: Frequency and etiology of surgical spleen injuries, treatment options, frequency of splenectomy, associated postoperative morbidity (POM) and mortality, recommendation for splenectomy. Classification... |
Tipo: Journal article |
Palavras-chave: "Splenectomy"; "Digestive System Surgical Procedures"; Gastrointestinal Surgical Procedures; Antireflux surgery; Postoperative morbidity. |
Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000400058 |
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Manterola,Carlos; Otzen,Tamara; Lorenzini,Nicolas; Díaz,Andrés; Torres-Quevedo,Rodrigo; Claros,Nataniel. |
La calidad del reporte de los resultados de una investigación no es óptima, razón por la cual, se han desarrollado numerosas iniciativas tendientes a mejorar este aspecto a lo largo de los años. El objetivo de este artículo es mencionar y describir las iniciativas existentes para el reporte de resultados de investigación biomédica en diversos escenarios de investigación clínica y situaciones especiales. Se realizó una búsqueda en las bases de datos THE COCHRANE LIBRARY, MEDLINE, SciELO y Redalyc; y en los buscadores Clinical Evidence, TRIP database, Fisterra, Rafabravo, EQUATOR Network, portal de BIREME y Programa HINARI; para obtener las listas de verificación existentes. Los documentos recuperados fueron agrupados de la siguiente forma: relacionados con... |
Tipo: Journal article |
Palavras-chave: Reporte de resultados; Listas de verificación; Terapia; Diagnóstico; Pronóstico; Evaluaciones económicas. |
Ano: 2013 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000300029 |
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Otzen,Tamara; Manterola,Carlos. |
La representatividad de una muestra, permite extrapolar y por ende generalizar los resultados observados en ésta, a la población accesible; y a partir de ésta, a la población blanco. Por ende, una muestra será representativa o no; sólo si fue seleccionada al azar, es decir, que todos los sujetos de la población blanco tuvieron la misma posibilidad de ser seleccionados en esta muestra y por ende ser incluidos en el estudio; y por otro lado, que el número de sujetos seleccionados representen numéricamente a la población que le dio origen respecto de la distribución de la variable en estudio en la población, es decir, la estimación o cálculo del tamaño de la muestra. Es así como el análisis de una muestra permite realizar inferencias, extrapolar o generalizar... |
Tipo: Journal article |
Palavras-chave: Muestreo; Técnicas de muestreo; Muestreo aleatorio; Muestreo sistemático; Muestreo estratificado; Muestreo por conglomerados; Inferencia. |
Ano: 2017 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000100037 |
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Manterola,Carlos; Otzen,Tamara. |
Echinococcosis is an endemic zoonosis in the south of Chile; we therefore have occasion to treat a large number of patients, particularly in the liver. Hepatic echinococcosis (HE) has its own morbidity and mortality due to evolutionary complications, to which the risk of complications related to the surgical procedures is added, the morbidity which has been reported up to 80 %. This is associated with a history of previous surgeries for HE, evolutionary complications of the cyst, the need for additional procedures such as the treatment of the disease in other simultaneous locations, etc. Moreover, reported mortality is up to 10 %, a situation that remains unchanged despite technological and therapeutic advances. The surgical treatment of HE can be divided... |
Tipo: Journal article |
Palavras-chave: Echinococcosis; Hydatidosis; Echinococcosis; Hepatic Echinococcosis; Hepatic/surgery; Hepatic Hydatid Cyst; Pericystectomy; Hepatic resections; Capitonnage; Omentoplasty. |
Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000200044 |
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Sanhueza,Antonio; Otzen,Tamara; Manterola,Carlos; Araneda,Nelson. |
In experimental studies the outcome variable is measured at initial time, usually called "baseline", and then in several times called "follow-up" measurement(s). The study question of interest in an experimental study is whether there is a significant difference effect between treatment and comparison group, after intervention. In addition, one wants to estimate the difference effect between groups. This paper studies some of the strategies, including a simulation process, that one can be used for analyzing data coming from an experimental study as above, and considers using or not using the baseline measurements. Three parametric and two non-parametric strategies are evaluated considering only one follow-up measurement. The baseline measurement is... |
Tipo: Journal article |
Palavras-chave: Experimental Studies; Follow-Up Studies; Biostatistics; Statistics; Nonparametric. |
Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000100054 |
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Manterola,Carlos; Cartes-Velasquez,Ricardo; Otzen,Tamara. |
Globally, the assessment of methodological quality (MQ) in biomedical research is an area of dynamic development over recent years. Understood as a complex and multidimensional construct, various groups have proposed tools for its assessment. Our team has designed and validated scales to assess MQ of therapy and prognosis studies. However, as with other instruments, it is necessary to specify in detail how it is applied, in such a way as to be able to standardize the measurements made with this instrument. A detailed description is presented of the 3 domains (type of research design [single item domain], size of population studied [single item domain], and methodology 7 items) and 9 items comprising the scale, specifying for each item how to assess the... |
Tipo: Journal article |
Palavras-chave: Investigative Techniques; Methods/epidemiology; Methodological studies; Diagnosis; Diagnostic tests; Reproducibility of Results; Evaluation Studies as Topic; Epidemiological Studies; Evidence-Based Medicine. |
Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000100012 |
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Manterola,Carlos; Otzen,Tamara. |
Echinococcus Granulosus (EG) is the major cause of cystic echinococcosis in humans and livestock in the world. In Chile is a zoonosis of great importance. The most frequently affected geographic areas are the Regions of Aysén, Los Rios, Los Lagos, Coquimbo and the Araucanía. Hence, it was discovered that in endemic areas of hydatidosis there could be several strains and genotypes of EG. In addition, there is evidence that some strains and genotypes are more infectious for human beings than others. This interesting phenomenon of the biology of EG has been studied using molecular biology techniques based on polymerase chain reaction (PCR) and DNA sequence analysis, which has made it possible to characterize the cestode species complex called EG sensu lato (s... |
Tipo: Journal article |
Palavras-chave: Echinococcus granulosus; Genotypes; Cytochrome c oxidase subunit I; PCR-RAPD. |
Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000400048 |
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Manterola,Carlos; Cartes-Velasquez,Ricardo; Otzen,Tamara. |
The assessment of methodological quality (MQ) in biomedical research is an area of dynamic development over recent years globally. Understood as a complex and multidimensional construct, various groups have proposed tools for its assessment. Our team has designed and validated scales to assess MQ of therapy, diagnosis, and prognosis studies. However, as with other instruments, it is necessary to specify in detail how it is applied, in order to standardize the measurements made with this instrument. The aim of this article is to provide a guideline for the standardized application of the MInCir MQ scale for therapy or therapeutic procedure studies. A detailed description of the 3 domains and 6 items comprising the scale, specifying for each of them how to... |
Tipo: Journal article |
Palavras-chave: Investigative Techniques; Methods/epidemiology methodological studies; Therapy; Intervention studies; Evaluation Studies as Topic; Epidemiologic Studies; Evidence-Based Medicine. |
Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000400045 |
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Manterola,Carlos; Otzen,Tamara. |
Los estudios experimentales, se caracterizan por la valoración del efecto de una o más intervenciones, habitualmente de forma comparativa con otra intervención, o un placebo; y el carácter prospectivo, de la recolección de los datos y el seguimiento de los grupos en estudio. Bajo la denominación de estudios experimentales, existe una diversidad de diseños, desde los ensayos clínicos (EC) y sus variantes, hasta los estudios cuasi-experimentales y los experientos naturales. El objetivo de este manuscrito, es reportar los principios básicos, características y estructura de un EC. |
Tipo: Journal article |
Palavras-chave: Estudios experimentales; Ensayo clínico; Asignación aleatoria; Enmascaramiento. |
Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000100054 |
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Manterola,Carlos; Otzen,Tamara; Calo,Lilian. |
Despite the large amount of information available on the Internet, getting valid scientific information and evidence may not be a simple task. The aim of this study was to identify the different databases, search engines and libraries available to retrieve published scientific information in health sciences Database publication type. A search on Altavista, Google and Yahoo, Ixquick and Copérnico metasearch engines and in the database "Documents in Information Science" (DoIS) was performed. The search strategy used the terms "database management systems", "medical informatics", "search engine" and "decision making". A summary document of the information collected was created. Addresses found were grouped into: databases, search engines and libraries. The... |
Tipo: Journal article |
Palavras-chave: Database; Publication Type; Medical Informatics; Search engine; Decision making; Evidence-Based Medicine. |
Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000400057 |
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Manterola,Carlos; Otzen,Tamara; Cartes-Velásquez,Ricardo; del Sol,Mariano; Olate,Sergio; Romero,Fernando; Astudillo,Paula. |
The number of doctoral programs in the biomedical field has risen in recent decades, but with a concentration in Santiago and little expansion into the provinces. The aim of this article is to describe the initial results obtained by the Doctorate in Medical Sciences program of the Universidad de La Frontera, Chile. Observational study, conducted in the Department of Surgery at the Universidad de La Frontera, Chile. All cohorts in the program from 2008 to 2015 were included. The outcome variables were: Graduation rate and scientific productivity of the graduates (WoS and SciELO publications). Other variables of interest were: academic faculty productivity (WoS and SciELO publications), and characteristics of students who entered the program (age, sex,... |
Tipo: Journal article |
Palavras-chave: Education Graduate Education; Medical; Graduate Education; Dental; Graduate Education; Medical Education; Medical; Continuing Doctorate programs Ph.D. programs Postdoctoral programs. |
Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000300058 |
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Registros recuperados: 24 | |
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