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	Provedor de dados Anais da ABC (AABC) (2) Autor Dolabela,Maria Fâni (2) Póvoa,Marinete M. (2) Braga,Fernão C. (1) Jácome,Rose L.R.P. (1) Nascimento,José M.S. (1) Oliveira,Alaide B. (1) Oliveira,Alaíde B. (1) Oliveira,Salma G. (1) Peres,José M. (1) Varotti,Fernando P. (1) Mais... Palavra-chave Antimalarial activity (2) Alkaloids (1) Apocynaceae (1) Aspidosperma spp. (1) In vitro assays (1) Medicinal plants (1) Natural products (1) Phytomedicines (1) Plasmodium falciparum (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2012 (1) 2009 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última In vitro antimalarial activity of six Aspidosperma species from the state of Minas Gerais (Brazil) Anais da ABC (AABC) Dolabela,Maria Fâni; Oliveira,Salma G.; Peres,José M.; Nascimento,José M.S.; Póvoa,Marinete M.; Oliveira,Alaide B.. Ethnomedicinal informations point to some Aspidosperma species (Apocynaceae) as antimalarial plants in Brazil and have motivated the evaluation of six species which were collected in the state of Minas Gerais: A. cylindrocarpon Müll. Arg., A. parvifolium A. DC., A. olivaceum Müll. Arg., A. ramiflorum Müll. Arg., A. spruceanum Benth. ex Müll. Arg. and A. tomentosum Mart.. A total of 23 extracts of different plant parts in different solvents were assayed in vitro against chloroquine-resistant (W2) and chloroquine-sensitive (3D7) strains of Plasmodium falciparum. All the extracts were shown to be active with IC50 values in the range of 5.0 ± 0 2.8 µg/mL to 65.0 ± 4.2 µg/mL. TLC profile of the extracts revealed the presence of alkaloids in the six species... Tipo: Info:eu-repo/semantics/article Palavras-chave: Antimalarial activity; Plasmodium falciparum; In vitro assays; Aspidosperma spp.; Apocynaceae. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652012000400005 Plant-derived antimalarial agents: new leads and efficient phythomedicines. Part I. Alkaloids Anais da ABC (AABC) Oliveira,Alaíde B.; Dolabela,Maria Fâni; Braga,Fernão C.; Jácome,Rose L.R.P.; Varotti,Fernando P.; Póvoa,Marinete M.. Malaria remains one of the most serious world health problem and the major cause of mortality and morbidity in the endemic regions. Brazil is among the 30 high-burden countries and most of the cases occur in the Legal Amazonian Region. New chemotherapeutical agents are needed for the treatment of malaria. Many plant species are used in traditional medicines of malarious countries and a relatively few number of these have been investigated for evaluation of their antimalarial effect. Still lower is the number of those that have had the active natural compounds isolated and the toxicity determined. This area is, then, of great research interest. discovery project of antimalarial natural products from plants traditionally used to treat malaria must include in... Tipo: Info:eu-repo/semantics/article Palavras-chave: Natural products; Alkaloids; Antimalarial activity; Medicinal plants; Phytomedicines. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000400011 Registros recuperados: 2 Primeira ... 1 ... Última

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