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| Araújo,Cleiber Lucan Alves; Salles,Bruno Cesar Correa; Duarte,Stella Maris da Silveira; Rodrigues,Maria Rita; Paula,Fernanda Borges de Araújo. |
| This study was conducted to evaluate the effect of extracts of Passiflora edulis Sims leaves on the oxidative metabolism of rat peritoneal neutrophils using a model of acute inflammation. The extract was obtained by maceration in 70% ethanol, evaporation under reduced pressure and lyophilisation. Total phenolic content (TP) was determined by the Folin-Ciocalteu assay. The P. edulis extract, in different doses, was administered by gavage 1 h prior to inflammation induction by carrageenan (8 mg/kg, i.p.); five hours later, the neutrophils were obtained by intraperitoneal lavage. The tests performed in neutrophils were cytochrome C and chemiluminescence assay as well as myeloperoxidase (MPO), superoxide dismutase (SOD), glutathione peroxidase (GPx) and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Passiflora edulis Sims; Inflammation; Neutrophil; Reactive oxygen species (ROS); Antioxidant enzymes. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100562 |
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| Martins,Carolina Fernandes Ribas; Salles,Bruno César Corrêa; Brigagão,Maisa Ribeiro Pereira Lima; Rodrigues,Maria Rita; Ferreira,Eric Batista; Duarte,Stella Maris da Silveira; Paula,Fernanda Borges de Araujo. |
| abstract This study was conducted to evaluate the effects of the ethanolic extract of Passiflora edulis leaves on blood glucose, protein glycation, NADPH oxidase activity and macrophage phagocytic capacity after Candida albicans exposure in diabetic rats. The Passiflora edulis Sims leaves were dried to 40°C, powdered, extracted by maceration in 70% ethanol, evaporated under reduced pressure and lyophilised. The biochemical tests performed were total phenolic content (TP) as determined by the Folin-Ciocalteu assay, trapping potential DPPH assay and total iron-reducing potential. Diabetes was induced by alloxan injection. Protein glycation was determined by AGE and fructosamine serum concentrations. Extract-treated diabetic animals demonstrated lower... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Passiflora edulis Sims/pharmacognosy; Passiflora edulis Sims/ethanolic extract/effects; Blood glucose; Protein glycation; Reactive oxygen species; Diabetes/treatment/experimental study; Medicinal plants.. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000400869 |
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