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Newcastle disease virus vaccine strains: immunogenicity is not influenced by ICPI Rev. Bras. Ciênc. Avic.
Orsi,MA; Doretto Júnior,L; Reischak,D; Silva,LHA da; Spilki,FR; Buzinaro,MG; Arns,CW.
Intracerebral pathogenicity index (ICPI) and mean death time (MDT) were determined using commercial live vaccines against Newcastle disease available in Brazil. The ICPI profiles obtained for B1 vaccine strains were nonvirulent and varied from 0 to 0.19, and their MDT was 104-116 hours. The LaSota strains had an ICPI varying between 0.02 and 0.37 and MDT from 92 to 116 hours. ICPI and MDT for the Clone 30 were 0.11 and 104 hours, respectively. For Ulster vaccines, ICPI and MDT were 0 and >150 hours; for VG-GA was 0.03 and 140 hours; and for C2, 0.04 and >144 hours. Eye drop vaccination and IM challenge, at the 1st week and the 4th week, respectively, resulted in highest protection for B1 (95-100%) and LaSota (90-100%) strains. The variability in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Newcastle disease virus (NDV) vaccines; Intracerebral pathogenicity index (ICPI); Mean death time (MDT).
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2009000200009
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