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Fetal Central Nervous System and Thymic Alterations Following Cyclophosphamide Treatment of Pregnant Mice International Journal of Morphology
Prakash,; Singh,Gajendra; Singh,Sukh Mahendra.
The present study assessed central nervous system (CNS) and immune system changes in murine fetuses after cyclophosphamide (CP) exposure during intrauterine life. A single CP dose of 0, 10, or 20mg/kg body weight was administered by intraperitoneal inj ection to pregnant mice (20/group) on day 11 of gestation (GD 11) and fetuses were evaluated on day 19 of gestation (GD 19). Fetuses were examined for external changes, and then the brains and thymuses were removed for further evaluations of histological changes, protein content, apoptotic cell count, DNA fragmentation, and in vitro cell proliferation using 1 fetus/litter for each assessment. Brains and thymuses from CP-exposed fetuses were smaller in size and distorted in overall shape compared to those...
Tipo: Journal article Palavras-chave: Cyclophosphamide; Brain; Thymus; Mice; Teratology.
Ano: 2007 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000400016
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Morphometry of Vertebral Pedicles: a Comprehensive Anatomical Study in the Lumbar Region International Journal of Morphology
Prakash,; Prabhu,Latha V; Vadgaonkar,Rajanigandha; Pai,Mángala M; Ranade,Anu V; Singh,Gajendra.
This comprehensive anatomical study on bones and X-rays regarding pedicles of lumbar vertebrae was performed in two parts. In the first part of the present work direct gross measurements of 3 different diameters (v, d, and 1) of both the pedicles of LI to L5 vertebrae (200 male and 200 female) were recorded through sliding vernier caliper. In the second part plain anteroposterior radiographs of the lumbar spine from 500 individuals (250 males and 250 females) were collected, and divided in 6 age groups and 2 different diameters (t and h) were recorded. The minimum horizontal diameter (d) of both the pedicles increased from LI to L5. Whereas, the vertical height (v) of both the pedicles increased from LI to L2, decreased from L2 to L3 and increased from L3...
Tipo: Journal article Palavras-chave: Pedicle; Vertebra lumbar; Spine; Morphometry.
Ano: 2007 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000200026
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Histological Changes in Ovaries of Mice Exposed to Butea monosperma: Preliminary Study International Journal of Morphology
Gupta,Neelam; Singh,Gajendra; Singh,S. M; Reddy,K. R. C.
In Ayurvedic practice Butea monosperma (Palash) is in clinical use for hundreds of years as a contraceptive. Seeds of Butea monosperma are also used as an anthelmitic (Ansani et al., 1979) and antimicrobial (Avirutnant & Pongpan, 1983). Butea monosperma (Fabaceae family) locally known as Palash (Dhak) if given for 3 consecutive days acts as an antifertility agent for which it has been is traditionally used since time immemorial. The objective of the present study was to search the effect of Butea monosperma seeds on the ovary of mice. Observations in the present study were massive degeneration of ova in almost all the follicles, irrespective of the stage of their development. The ova from treated animals showed different stages of necrotic process....
Tipo: Journal article Palavras-chave: Palash; Butea monosperma; Apoptosis; Disintegration; Follicles.
Ano: 2010 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000400051
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A Variation of Phrenic Nerve: Case Report and Review International Journal of Morphology
Prakash,; Prabhu,Latha V; Kumar,Jwalaram; Madhyastha,Sampath; Singh,Gajendra.
During routine dissection in the Department of Anatomy following anatomical variations of phrenic nerve were observed on right side in the neck region of a middle aged cadaver. The phrenic nerve in its early course close to its origin was giving a communicating branch to C5 root of brachial plexus and at the level of the root of neck just before entering the thorax, the phrenic nerve was placed anterior to the subclavian vein. This unique case of phrenic nerve variation gains tremendous importance in context of subclavian vein cannulation, implanted venous access portals, and supraclavicular nerve block for regional anesthesia
Tipo: Journal article Palavras-chave: Phrenic nerve; Neck; Anatomical variations.
Ano: 2006 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000500029
Registros recuperados: 4
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