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Queiroz-Neto,A.; D'Angelis,F.H.F.; Harkins,J.D.; Tobin,T.. |
With the aim of determining the possible toxicity of amitraz after its prolonged use in horses, six English Thoroughbred horses received intravenous injections of amitraz (0.05, 0.10 or 0.15 mg/kg) weekly for four months, constituting the experimental group. Eight other animals (control group), via the same route following the same drug administration schedule and period of time, received the vehicle, dimethylformamide. At the end of this period, blood was collected from all the animals, and a comparison was made of the means of the values obtained for the various blood analyses: complete hemogram, alkaline phosphatase, gamma-glutamyltransferase, blood urea nitrogen, lactate dehydrogenase, aspartate aminotransferase, creatine phosphokinase, glucose,... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Horse; English Thoroughbred; Amitraz; Toxicity; Blood characteristics; Electrolytes. |
Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352002000400003 |
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Queiroz-Neto,A.; Carregaro,A.B.; Zamur,G.; Harkins,J.D.; Tobin,T.; Mataqueiro,M.I.; Gonçalves,S.C.. |
The effect of the intravenous injection of amitraz (0.1mg/kg) to horses on cardiac activity, respiratory rate, intestinal motor activity, rectal temperature, sweating and masticating was evaluated and compared to the effect of intravenous administration of xylazine (1mg/kg, iv) on heart rate, respiratory rate and intestinal activity. Amitraz caused a significant decrease in heart activity, respiratory rate and intestinal movements, but these effects were not as pronounced as those caused by xylazine. Amitraz also caused a significant relaxation of the rectal smooth muscle, and an apparent increase in sweating and in the frequency of horses found masticating hay. Rectal temperature was not influenced by amitraz. The results indicated that amitraz, at the... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Horse; Amitraz; Xylazine; Cardiac activity; Respiratory activity; Intestinal activity. |
Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352000000100008 |
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