SABIIA - Sistema Aberto e Integrado de Informação em Agricultura (Sabiia)

Toledo,Paula Virginia Michelon; Tuon,Felipe Francisco; Arend,Lavinia; Aranha Junior,Ayrton Alves.

Acute pancreatitis associated with lamivudine therapy for chronic B hepatitis

Ano: 2014

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000500574

Tuon,Felipe Francisco; Guastini,Cristina Maria de Fátima; Boulos,Maria Ivete Castro.

Hyperamylasemia is a common complication during lamivudine use. We report a case of a pancreatitis following lamivudine therapy. A careful monitoring of amylase levels during treatment with lamivudine is discussed, mainly in the first weeks, considering the cost of this exam and further complication.

Sex, drugs, bugs, and age: rational selection of empirical therapy for outpatient urinary tract infection in an era of extensive antimicrobial resistance

Palavras-chave: Lamivudine; Pancreatitis; Amylases; Hyperamilasemina; Hepatitis; Chronic B hepatitis.

Ano: 2008

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000400001

Rocha,Jaime L.; Tuon,Felipe Francisco; Johnson,James R..

BACKGROUND: Optimal empirical therapy of urinary tract infection requires accurate knowledge of local susceptibility patterns, which may vary with organism and patient characteristics. METHODS: Among 9,798 consecutive, non-duplicate, community-source urine isolates from ambulatory patients > 13 years old, from clinical laboratory and an academic medical center in Curitiba, Brazil (May 1st to December 1st, 2009), susceptibility data for ampicillin, nitrofurantoin, trimethoprim-sulfamethoxazole, gentamicin, fluoroquinolones, and ceftriaxone/cefotaxime were compared with organism and patient gender and age. RESULTS: The female-to-male ratio decreased with age, from 28.1 (among 20-29 year-olds) to 3.3 (among > 80 year-olds). Overall, susceptibility...

Outbreak of vancomycin-resistant Enterococcus in a renal transplant unit

Palavras-chave: Urinary tract infections; Anti-bacterial agents; Drug resistance bacterial; Fluoroquinolones; Escherichia coli.

Ano: 2012

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000200002

Tuon,Felipe Francisco; Penteado-Filho,Sergio Ricardo; Camilotti,Janaina; Heijden,Inneke Marie van der; Costa,Silvia Figueiredo.

Human immunodeficiency virus and hepatitis C virus/hepatitis B virus co-infection in Southern Brazil: clinical and epidemiological evaluation

Ano: 2011

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000400021

Raboni,Sonia Mara; Tuon,Felipe Francisco; Beloto,Nayara Carvalho Polido; Demeneck,Henrique; Oliveira,Andre; Largura,Denis; Sagrado,Andressa Gervasoni; Lima,Bárbara Perdonsini; Franzoni,João Paulo; Pedroso,Maria Lucia.

Hepatitis B virus, hepatitis C virus and human immunodeficiency virus share a similar transmission pathway and are often diagnosed in the same patient. These patients tend to have a faster progression of hepatic fibrosis. This cross-sectional study describes the demographic features and clinical profile of human immunodeficiency virus/hepatitis co-infected patients in Parana, Southern Brazil. A total of 93 human immunodeficiency virus-infected patients attending a tertiary care academic hospital in Southern Brazil were included. Clinical, demographic and epidemiological data were evaluated. Hepatitis B virus and/or hepatitis C virus positive serology was found in 6.6% of patients. The anti-hepatitis C virus serum test was positive in 85% (79/93) of...

Tipo: Info:eu-repo/semantics/report

Palavras-chave: Human immunodeficiency virus; Hepatitis B; Hepatitis C; Co-infection.

Ano: 2014

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000600664

Fosfomycin in vitro resistance of Escherichia coli from the community

Biondo,Caroline M; Rocha,Jaime L; Tuon,Felipe Francisco.

Klebsiella ESBL bacteremia-mortality and risk factors

Ano: 2011

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000100021

Tuon,Felipe Francisco; Kruger,Margot; Terreri,Marcos; Penteado-Filho,Sergio R; Gortz,Lucas.

Background: Extended spectrum β-lactamase (ESBL)-producing bacteria have become recognized as a problem in South America. The aim of this study was to evaluate risk factors and mortality rate in bacteremia caused by ESBL-producing Klebsiella pneumoniae in a Brazilian hospital. Methods: A three-year retrospective cohort study with 104 cases of K. pneumoniae bacteremia (61 ESBL and 43 non-ESBL). Several clinical and laboratory variables were evaluated. The outcome of interest was 30-day mortality. The adequate treatment was evaluated according to antibiotic susceptibility. Results: Multivariable analysis showed that central venous catheter and mechanical ventilation were independent risk factors for ESBL. The duration of hospitalization before the bacteremia...

Daptomycin to bone and joint infections and prosthesis joint infections: a systematic review

Palavras-chave: Klebsiella pneumoniae; Beta-lactamases; Bacteremia; Carbapenems.

Ano: 2011

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000600016

Telles,João Paulo; Cieslinski,Juliette; Tuon,Felipe Francisco.

ABSTRACT Backgroud: Daptomycin has been used in bone and joint infections (BJI) and prosthesis joint infections (PJI) considering spectrum of activity and biofilm penetration. However, the current experience is based on case reports, case series, cohorts, and international surveys. The aim of this systematic review was to evaluate studies about daptomycin treatment efficacy in BJI/PJI compared to other antibiotic regimens. Methods: PubMed, LILACS, Scielo and Web of Science databases were searched for articles about daptomycin and treatment of BJI and PJI from inception to March 2018. Inclusion criteria were any published researches that included patients with BJI treated with daptomycin. Diagnosis of BJI was based on clinical, laboratory and radiological...

Mobile health application to assist doctors in antibiotic prescription - an approach for antibiotic stewardship

Palavras-chave: Daptomycin; Staphylococcus aureus; Osteomyelitis; Joint infection; Arthritis.

Ano: 2019

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000300191

Tuon,Felipe Francisco; Gasparetto,Juliano; Wollmann,Luciana Cristina; Moraes,Thyago Proença de.

ABSTRACT Background: Technologies applied to mobile devices can be an important strategy in antibiotic stewardship programs. Objective: The aim of this study was to determine the impact of a decision-making application on antibiotic prescription. Methods: This was an observational, analytical and longitudinal study on the implementation of an antimicrobial guide for mobile application. This study analyzed the period of 12 months before and 12 months after the app implementation at a university hospital based on local epidemiology, avoiding high cost drugs and reducing the potential for drug resistance including carbapenem. Antimicrobials consumption was evaluated in Daily Defined Dose/1000 patients-day and direct expenses converted into USD. Results:...

Mortality rate in patients with nosocomial Acinetobacter meningitis from a Brazilian hospital

Palavras-chave: Mobile health applications; Stewardship; Antibiotic; Infection control.

Ano: 2017

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000600660

Tuon,Felipe Francisco; Penteado-Filho,Sergio R; Amarante,Diogo; Andrade,Marcio A; Borba,Luis A.

BACKGROUND: The mortality rate due to Acinetobacter baumannii nosocomial meningitis (ANM) is high. OBJECTIVE: The aim of this study was to evaluate the factors that have influence over the outcomes in ANM patients. METHODS: A retrospective analysis of 22 cases of ANM was conducted in a hospital with high incidence of multidrug resistance. RESULTS: The mean age of patients was 43 years (21 to 91) and 54.5% were male. All ANM cases occurred within 60 days of admission and the mean duration of illness was of 18.2 days. All cases were associated with previous neurosurgical procedures: elective surgery (27.2%), external shunt (54.4%) and emergency surgery due to trauma (18.1%). Imipenem resistance was observed in 40.9% of cases, but ampicillin/sulbactam...

Palavras-chave: Acinetobacter; Meningitis; Acinetobacter baumannii; Neurosurgery; Imipenem; Ampicillin/sulbactam.

Ano: 2010

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000500003

Paragonimiasis in Brazil

Tuon,Felipe Francisco; Amato,Valdir Sabbaga; Amato Neto,Vicente.

Bacteremia and meningitis caused by OXA-23-producing Acinetobacter baumannii – molecular characterization and susceptibility testing for alternative antibiotics

Ano: 2008

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000100001

BJM

Schuertz,Kamile Francine; Tuon,Felipe Francisco; Palmeiro,Jussara Kasuko; Conte,Danieli; Telles,João Paulo Marochi; Trevisoli,Lucas Eduardo; Dalla-Costa,Libera Maria.

Abstract Background: Carbapenem-resistant Acinetobacter baumannii infection is a concern in developing countries due to high incidence, few therapeutic options, and increasing costs. Objective: Characterize and analyze the antibiotic susceptibility patterns of carbapenem-resistant A. baumannii isolates and evaluate clinical data of meningitis and bacteremia caused by this microorganism. Methods: Twenty-six A. baumannii isolates from 23 patients were identified by MALDI-TOF and automated methods and genotyped using pulsed field genotyping electrophoresis. Clinical data and outcomes were evaluated. Susceptibility of isolates to colistin, tigecycline, meropenem, imipenem, and doxycycline was determined. Results: Mortality due to A. baumannii infections...