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| Onishi, Kenji; Sarumoh, Bolu Muhammad; Hagiwara, Daisuke; Watanabe, Akira; Kamei, Katsuhiko; Toyotome, Takahito. |
| Azole-resistant strains of Aspergillus fumigatus containing a tandem repeat in the cyp51A promoter and amino acid substitution(s) have been isolated in the environment worldwide; however, this type of resistant strain had never been isolated from the environment in Japan. Our previous study indicated that an azole-resistant A. fumigatus strain OKH50 containing a 34-bp tandem repeat in cyp51A promoter with L98H substitution in Cyp51A was isolated from a patient in Obihiro of Hokkaido, Japan. In this study, we collected azole-resistant Aspergillus spp. by air sampling from the environment in Japan. One Aspergillus-like colony was isolated from one of 10 sampling sites surveyed. The strain Env1 was confirmed as A. fumigatus by nucleotide sequencing and... |
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Palavras-chave: Aspergillus fumigatus; Azole; Cyp51A; TR34/L98H. |
| Ano: 2017 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4565 |
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| Iwasa, Mitsuhiro; Maruyama, Masumi; Nakamura, Eri; Yamashita, Nobuo; Watanabe, Akira; 岩佐, 光啓. |
| The effects of antiparasitic drug, ivermectin, on the dung-breeding flies were studied in laboratory and field experiments in Hokkaido, Japan. In two pour-on treatments (500μg/kg), ivermectin was excreted in dung for up to 14 and 21 days after treatment, with peaks at 3 days and 1 day, respectively. Dung from treated cattle prevented the larval development of Haematobia irritans and Neomyia cornicina up to 14 days and reduced the larval and pupal survival rates at 21 days after treatment. In the field experiment using emergence traps, the numbers of emerged flies from dung pats were 3,655 (18 families) in control dung and 2,234 (16 families) in treated dung. Especially, Musca bezzii, Ravinia striata, Sepsis duplicata, Sepsis thoracica, Sepsis cynipsea,... |
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Palavras-chave: Ivermectin; Pour-on; Haematobia irritans; Neomyia cornicina; Non-target species; Dung-breeding flies. |
| Ano: 2005 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/651 |
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