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| Cao,Xuebing; Hou,Dongzhi; Wang,Lei; Li,Sai; Sun,Shengang; Ping,Qineng; Xu,Yan. |
| BACKGROUND: Chitosan, the N-deacetylated derivative of chitin, is a cationic polyelectrolyte due to the presence of amino groups, one of the few occurring in nature. The use of chitosan in protein and drug delivery systems is being actively researched and reported in the literature RESULTS: In this study, we used chitosan-coated levodopa liposomes to investigate the behavioral character and the expression of phosphorylated extracellular signal-regulated kinase (ERK1/2), dopamine- and cAMP-regulated phos-phoprotein of 32 kDa (DARPP-32) and FosB/AFosB in striatum of rat model of levodopa-induced dyskinesia (LID). We found that scores of abnormal involuntary movement (AIM) decreased significantly in liposome group (P < 0.05), compared with levodopa group.... |
| Tipo: Journal article |
Palavras-chave: Dyskinesia; Levodopa liposomes; ERK1/2; DARPP-32; FosB/AFosB. |
| Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602016000100032 |
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| Mu,Xia; Xu,Yan; Yang,Tingxiu; Zhang,Ji; Wang,Chong; Liu,Wei; Chen,Jing; Tang,Luyu; Yang,Huai. |
| Abstract Objective Hand hygiene (HH) is a critical component for controlling hospital-acquired infection (HAI). The present study was designed to develop an intervention approach to improve compliance with HH among healthcare workers in a hospital setting. Methods The HH intervention study was conducted in Guizhou Provincial People's Hospital, Guiyang, China and organized by its Department of HAI Management. It was an observational, prospective, quasiexperimental (before-after intervention) study. The study was divided into two phases: the baseline phase and the intervention phase. The investigative team included clinical monitoring staff and infection control practitioners who received a series of instructions on HH compliance, monitoring skills, and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hand hygiene; Compliance; Hospital-acquired infection. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000500413 |
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