|
|
|
|
|
| Oliveira,Isadora S; Ferreira,Isabela G; Alexandre-Silva,Gabriel M; Cerni,Felipe A; Cremonez,Caroline M; Arantes,Eliane C; Zottich,Umberto; Pucca,Manuela B. |
| Abstract Scorpion venoms are natural sources of molecules that have, in addition to their toxic function, potential therapeutic applications. In this source the neurotoxins can be found especially those that act on potassium channels. Potassium channels are responsible for maintaining the membrane potential in the excitable cells, especially the voltage-dependent potassium channels (Kv), including Kv1.3 channels. These channels (Kv1.3) are expressed by various types of tissues and cells, being part of several physiological processes. However, the major studies of Kv1.3 are performed on T cells due its importance on autoimmune diseases. Scorpion toxins capable of acting on potassium channels (KTx), mainly on Kv1.3 channels, have gained a prominent role for... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Voltage-gated potassium channels; Kv1.3; Scorpion toxins; KTx; Immunosuppression. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100202 |
| |
|
|
| Rabelo,Guilherme Rodrigues; Marques,Jonas de Brito Campolina; Zottich,Umberto; Dias,Germana Bueno; Miguel,Emílio Castro; Gomes,Valdirene Moreira; Da Cunha,Maura. |
| Pachystroma longifolium is an evergreen species of Euphorbiaceae that occurs in tabuleiro forest, a type of lowland Atlantic Forest. The site chosen for this study was a fragment of tabuleiro forest that has a history of being selectively logged for timber. P. longifolium is very successful at colonizing disturbed areas in this forest fragment in comparison with preserved fragments. In the present work, which was based on using different microscopy (electron and light microscopy, X-ray analysis) and biochemistry techniques, we describe the leaf and latex traits of P. longifolium and their role as defense mechanisms against desiccation and herbivory. Our results suggest the richness of P. longifolium populations, in the disturbed forest area studied, is... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Anatomical strategies; Crystals; Cuticles; Laticifers; Leaf anatomy. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-33062011000100018 |
| |
|
|
| Miguel,Emilio de Castro; Pireda,Saulo; Barros,Claudia Franca; Zottich,Umberto; Gomes,Valdirene Moreira; Miguens,Flavio Costa; Cunha,Maura Da. |
| ABSTRACT Secretory structures are formed by many types of plants and are present on numerous different organs. Among the many types of known secretory structures, colleters are predominant on plants of the Rubiaceae. One remarkable characteristic of secretory tissues is the export of exudates; however, the precise mechanism involved in this process is still unclear. To better understand the mechanisms of exudate externalization it is necessary to understand the ultrastructure and dynamics of the outer cell wall of the secretory structures during the secretory process, and so we investigated these aspects of the colleters of Bathysa nicholsonii. The outer cell wall (OCW) exhibits multiple layers: a basal polysaccharide rich layer; a cuticular membrane,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Colleters; Outer cell wall; Rubiaceae; Secretion accumulation site; Secretion mechanism; Secretory structures; Secretory tissues. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-33062017000300411 |
| |
|
|
|
