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	Provedor de dados Anais da ABC (AABC) (1) Biol. Res. (1) Genet. Mol. Biol. (1) Autor ALBALA,CECILIA (1) AYUSO,DOLORES (1) CIFUENTES,MARIANA (1) Carolina,Romero (1) Fernando,Lizcano (1) GONZÁLEZ,ANA (1) IZQUIERDO,MERCEDES (1) PEÑA,FRANCISCO (1) ROJAS,CECILIA V (1) Vargas,Diana (1) Mais... Palavra-chave Adipocyte (3) Backfat thickness (1) Cholesterol (1) Deacetylation (1) Demethylation (1) Extensive (1) Histones (1) Intramuscular fat (1) JMJD2C (1) Lipogenesis (1) Lipolysis (1) Obesity (1) PPARγ (1) Trichostatin A (1) Triglyceride metabolism (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Journal article (1) Ano 2018 (1) 2011 (1) 2008 (1) País Brazil (2) Chile (1) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Regulation of adipogenesis by nucelar receptor PPARγ is modulated by the histone demethylase JMJD2C Genet. Mol. Biol. Fernando,Lizcano; Carolina,Romero; Vargas,Diana. A potential strategy to combat obesity and its associated complications involves modifying gene expression in adipose cells to reduce lipid accumulation. The nuclear receptor Peroxisome Proliferator-activated receptor gamma (PPARγ) is the master regulator of adipose cell differentiation and its functional activation is currently used as a therapeutic approach for Diabetes Mellitus type 2. However, total activation of PPARγ induces undesirable secondary effects that might be set with a partial activation. A group of proteins that produce histone demethylation has been shown to modify the transcriptional activity of nuclear receptors. Here we describe the repressive action of the jumonji domain containing 2C/lysine demethylase 4 C (JMJD2C/KDM4C) on PPARγ... Tipo: Info:eu-repo/semantics/article Palavras-chave: PPARγ; Histones; Demethylation; JMJD2C; Deacetylation; Adipocyte; Trichostatin A. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000100004 Changes in adipose cells of Longissimus dorsi muscle in Iberian pigs raised under extensive conditions Anais da ABC (AABC) AYUSO,DOLORES; GONZÁLEZ,ANA; PEÑA,FRANCISCO; IZQUIERDO,MERCEDES. ABSTRACT Twenty-four Iberian castrated male pigs were used to characterize and evaluate the effect of the duration of “Montanera” in the adipocytes size and its relation with the backfat thickness and intramuscular fat. The animals were fed under extensive conditions during 30, 60 and 90 days in the “Dehesa” before slaughtered. Carcass weight, percentage of intramuscular fat, thickness of backfat and its three layers and adipocytes size of the intramuscular fat were obtained. The group which expended 90 days on fattening obtained the highest adipocytes, with an area higher by a 50% than those that only expended 30 days. The differences in diameter and perimeter adipocyte were not as marked as area. A significant positive correlation between the diameter,... Tipo: Info:eu-repo/semantics/article Palavras-chave: Extensive; Adipocyte; Backfat thickness; Intramuscular fat. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000100247 Differences in lipogenesis and lipolysis in obese and non-obese adult human adipocytes Biol. Res. CIFUENTES,MARIANA; ALBALA,CECILIA; ROJAS,CECILIA V. It has been proposed that differences in adipocyte function and/or metabolism between obese and lean individuáis may manifest themselves in functional adipose tissue abnormalities that lead to metabolic disorders in obesity. We studied lipogenesis and lipolysis of omental adipocytes from obese (OB) and non-obese (NOB) humans. The specific activity of the lipogenic marker enzyme G3PDH was 50% lower in total adipocytes of OB compared to that of NOB subjects. Omental adipocytes from OB subjects also had lower basal lipolytic levéis, and a lower lipolytic response to p-adrenergic stimulus. Cholesterol depletion of adipocyte plasma membrane using methyl β-cyclodextrin caused a lipolytic effect on adipocytes of both groups together, but when obese and... Tipo: Journal article Palavras-chave: Adipocyte; Cholesterol; Lipogenesis; Lipolysis; Obesity; Triglyceride metabolism. Ano: 2008 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000200009 Registros recuperados: 3 Primeira ... 1 ... Última

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