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| Santos,Kely Cristina dos; Kurtz,Stella Maris Tessaro Figura; Müller,Simony Davet; Biavatti,Maique Weber; Oliveira,Rúbia Maria Monteiro Weffort de; Santos,Cid Aimbiré de Moraes. |
| Leaves from several Passiflora species are largely employed in the Brazilian folk medicine as anxiolytic and sedative. In this work the anxiolytic, sedative-like properties and liquid chromatography analysis of methanolic extract of Passiflora actinia were evaluated. The methanol extract and all of its fractions presented significant sedative-like effect in elevated plus-maze and open field tests. Only the aqueous fraction of the methanol extract showed selective anxiolytic activity (30 mg/kg). Chromatographic analysis of the active fractions showed the presence of isovitexin and absence of the classical Passiflora beta-carboline alkaloids or flavonoids such as vitexin, rutin, swertisin, hesperidin and orientin. The tincture obtained from P. actinia leaves... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Anxiolytic; Sedative; Isovitexin; Passiflora actinia; Passifloraceae. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000500005 |
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