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| Registros recuperados: 45 | |
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| Furuoka, Hidefumi; Yabuzoe, Atushi; Horiuchi, Motohiro; Tagawa, Yuichi; Yokoyama, Takashi; Yamakawa, Yoshio; Shinagawa, Morikazu; Sata, Tetsutaro. |
| Monoclonal antibodies to the prion protein (PrP) have been of critical importance in the neuropathological characterization of PrP-related disease in men and animals. To determine the influence of species-specific amino-acid substitutions recognized by monoclonal antibodies, and to investigate the immunohistochemical reactivity of the latter, analyses were carried out on brain sections of cattle with bovine spongiform encephalopathy, sheep with scrapie, mice infected with scrapie, and human beings with Creutzfeldt-Jakob disease (CJD) or Gerstmann-Sträussler-Sheinker disease (GSS). Immunoreactivity varied between the antibodies, probably as the result of differences in the amino-acid sequence of the prion protein in the various species. Some monoclonal... |
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Palavras-chave: BSE; Cattle; CJD; GSS disease; Man; Mouse; Scrapie; Sheep. |
| Ano: 2007 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/1054 |
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| KADOHIRA, Mutsuyo; HILL, Glen; SAWADA, Manabu; YOSHIDA, Seiko; 門平, 睦代; ヒル, グレン; 澤田, 学; 吉田, 省子. |
| Since the first case of bovine spongiform encephalopathy (BSE) was encountered in Japan in 2001, the country quickly responded with a change from passive to active surveillance. The response has not been a smooth one, though, and news media have contributed to opening the public’s eyes to inadequate behavior from government sources responsible for monitoring and protecting the health of consumers. The resultant information“gap” has served to augment the typical Japanese perceptions of risk assessment, as assessed in surveys from 2003 to 2005. Such false beliefs have caused consumers to call for 100% testing of animals for BSE despite accepted scientific standards which do not support such comprehensive and costly surveillance. Instead, testing agencies... |
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Palavras-chave: BSE; Risk assessment; Surveillance; Risk perception; リスク評価; サーベイランス; リスク認知. |
| Ano: 2011 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3110 |
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