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Critical steps in the early evolution of the isocortex: Insights from developmental biology BJMBR
Aboitiz,F.; Montiel,J.; López,J..
This article proposes a comprehensive view of the origin of the mammalian brain. We discuss i) from which region in the brain of a reptilian-like ancestor did the isocortex originate, and ii) the origin of the multilayered structure of the isocortex from a simple-layered structure like that observed in the cortex of present-day reptiles. Regarding question i there have been two alternative hypotheses, one suggesting that most or all the isocortex originated from the dorsal pallium, and the other suggesting that part of the isocortex originated from a ventral pallial component. The latter implies that a massive tangential migration of cells from the ventral pallium to the dorsal pallium takes place in isocortical development, something that has not been...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cdk5; Dorsal ventricular ridge; Reelin; Tangential migration; Ventral pallium.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002001200006
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