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Nutritional programming by dietary carbohydrates in European sea bass larvae: not always what expected at juvenile stage ArchiMer
Zambonino-infante, Jose-luis; Panserat, S.; Servili, Arianna; Mouchel, Olivier; Madec, Lauriane; Mazurais, David.
Optimizing the metabolic use of these carbohydrate-rich plant products in fish feeds could be achieved through nutritional programming strategies of fish larvae. The present study aims at testing the long-term effect of an early-life high-carbohydrate nutritional (34% of starch in the feed) stimulus in European sea bass (Dicentrarchus labrax), by examining several biochemical and molecular parameters involved in carbohydrate metabolism in sea bass larvae and juveniles, compared to a control group fed standard larval regime (phase 1). As awaited, specific activities of digestive enzymes, from pancreatic and intestinal segments, involved in glucide digestion (amylase, sucrase) were enhanced together with an up-regulation of glucokinase gene and...
Tipo: Text Palavras-chave: Dicentrarchus labrax; Glucose metabolism; High-carbohydrate regimes; Marine fish larvae; Nutritional programming.
Ano: 2019 URL: https://archimer.ifremer.fr/doc/00470/58129/60552.pdf
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Early feeding of carnivorous rainbow trout (Oncorhynchus mykiss) with a hyperglucidic diet during a short period: effect on dietary glucose utilization in juveniles ArchiMer
Geurden, Inge; Aramendi, M; Zambonino, Jose-luis; Panserat, S.
Based on the concept of nutritional programming in higher vertebrates, we tested whether an acute hyperglucidic stimulus during early life could induce a long-lasting effect on carbohydrate utilization in carnivorous rainbow trout. The trout were fed a hyperglucidic diet (60% dextrin) at two early stages of development: either at first feeding Q days, stimulus 1) or after yolk absorption (5 days, stimulus 2). Before and after the hyperglucidic stimulus, they received a commercial diet until juvenile stage (> 10 g). Fish that did not experience the hyperglucidic stimuli served as controls. The short- and long-term effects of the stimuli were evaluated by measuring the expression of five key genes involved in carbohydrate utilization: a-amylase, maltase...
Tipo: Text Palavras-chave: Glucose metabolism; Intestinal glucose transport; Carbohydrate digestion; Nutritional programming; Fish nutrition.
Ano: 2007 URL: http://archimer.ifremer.fr/doc/2007/publication-2728.pdf
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The effects of dietary carbohydrate sources and forms on metabolic response and intestinal microbiota in sea bass juveniles, Dicentrarchus labrax ArchiMer
Gatesoupe, Joel; Huelvan, Christine; Le Bayon, Nicolas; Severe, Armelle; Aasen, Inga Marie; Degnes, Kristin F.; Mazurais, David; Panserat, Stephane; Zambonino, Jose-luis; Kaushik, Sadasivam.
The aim of this work was to investigate the catabolic process of three kinds of dietary carbohydrates in the gut of sea bass juveniles, with the possible contribution of the intestinal microbiota to the nutrition of the host, and the subsequent effects on intermediary metabolism. A first diet contained waxy maize (99% amylopectin), a highly digestible form of starch. A second diet was less quickly digestible due to its high amylose content of resistant starch. Two other diets contained fibre instead of starch, either only cellulose as control, or also other non-starch polysaccharides brought by lupin meal. The effect of the diets on the host confirmed previous results, with the stimulation of glucose storage in the liver in sea bass fed the starchy diets,...
Tipo: Text Palavras-chave: Digestive enzymes; Glucose metabolism; Intestinal microbiota; Viscerosomatic index; Gene expression; Metabolite analyses; Vegetable feedstuffs.
Ano: 2014 URL: http://archimer.ifremer.fr/doc/00166/27763/25944.pdf
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n-3 long chain polyunsaturated fatty acids: a nutritional tool to prevent insulin resistance associated to type 2 diabetes and obesity? ArchiMer
Delarue, Jacques; Lefoll, Christelle; Corporeau, Charlotte; Lucas, Daniele.
n-3 long chain polyunsaturated fatty acids (n-3 LC-PUFA), mainly eicosapentaenoic acid (EPA, 20:5 n-3) and docosahexaenoic acid (DHA, 22:6 n-3), are present in mammal tissues both from endogenous synthesis from desaturation and elongation of 18:3 n-3 and/or from dietary origin (marine products and fish oils). In rodents in vivo, n-3 LC-PUFA have a protective effect against high fat diet induced insulin resistance. Such an effect is explained at the molecular level by the prevention of many alterations of insulin signaling induced by a high fat diet. Indeed, the protective effect of n-3 LC-PUFA results from the following: (a) the prevention of the decrease of phosphatidyl inositol 3' kinase (PI3 kinase) activity and of the depletion of the glucose...
Tipo: Text Palavras-chave: Eicosapentaenoic acid (EPA); Docosahexaenoic acid (DHA); Peroxisome proliferator-activated receptors (PPAR); Non alcoholic steatohepatitis; Glucose metabolism; Insulin resistance.
Ano: 2004 URL: https://archimer.ifremer.fr/doc/00654/76580/77724.pdf
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Nutritional regulation and tissue specificity of gene expression for proteins involved in hepatic glucose metabolism in rainbow trout (Oncorhynchus mykiss) ArchiMer
Panserat, Stéphane; Plagnes Juan, E; Kaushik, Sadasivam.
Rainbow trout (Oncorhynchus mykiss) are known to use dietary carbohydrates poorly. One of the hypotheses to explain the poor utilisation of dietary glucose by these fish is a dysfunction in nutritional regulation of hepatic glucose metabolism. In this study, we obtained partial clones of rainbow trout cDNAs coding for a glucose transporter (Glut2), and for the enzymes 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (6PF-2K/F-2,6BPase), fructose-1,6-bisphosphatase (FBPase) and pyruvate kinase (PI(), Their deduced amino acid sequences were highly similar to those of mammals (up to 80% similarity), In a study of nutritional regulation, the Glut2 gene was highly expressed in the liver irrespective of the nutritional status of the trout, in agreement with...
Tipo: Text Palavras-chave: Oncorhynchus mykiss; Trout; Bifunctional enzyme; Pyruvate kinase; Fructose bisphosphatase; Glucose transporter; Glucose metabolism; Liver metabolism.
Ano: 2001 URL: http://archimer.ifremer.fr/doc/2001/publication-415.pdf
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Slow recovery of blood glucose in the insulin tolerance test during the prepartum transition period negatively impacts the nutritional status and reproductive performance postpartum of dairy cows. OAK
LEE, Hsu-Hsun; KIDA, Katsuya; MIURA, Ryotaro; INOKUMA, Hisashi; MIYAMOTO, Akio; KAWASHIMA, Chiho; HANEDA, Shingo; MIYAKE, Yoh-Ichi; MATSUI, Motozumi; 猪熊, 壽; 宮本, 明夫; 川島, 千帆; 羽田, 真悟; 松井, 基純.
In peripartum dairy cows, insulin resistance (IR) increases to adjust the direction of energy to lactation after calving. To investigate the effect of prepartum IR on postpartum reproductive performance, the insulin tolerance test (ITT) was applied to 15 cows at 3 weeks (Pre21) and 10 days (Pre10) before the predicted calving date. Blood glucose area under the curve (AUCglu) within 120 min after administration of 0.05 IU/kg-BW insulin was calculated. The occurrence of first ovulation, days to first artificial insemination (AI) and first AI conception rate were recorded. Nutritional status postpartum was evaluated by blood chemical analysis. Based on AUCglu changes from Pre21 to Pre10, cows were classified into either the AUC-up group (AUCglu increase, n=5)...
Palavras-chave: Dairy cows; Glucose metabolism; Insulin tolerance test; Reproductive performance; Transition period.
Ano: 2012 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4129
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MODELO TEÓRICO PARA EXPLICAR LA ACUMULACIÓN DE GOTAS LIPÍDICAS EN EMBRIONES BOVINOS MACHOS O HEMBRAS PRODUCIDOS in vitro Theoretical Model For Explaining Accumulation Of Fat Drops In In Vitro Produced Bovine Embryos Acta biol.Colomb.
CAMARGO,OMAR; RUIZ,TATIANA; OLIVERA,MARTHA.
La glucosa 6-fosfato deshidrogenasa (G6PD), codificada por un gen ubicado en el cromosoma X, es la enzima limitante de vía de las pentosas fosfato (PF). La entrada de la glucosa así como su flujo y el rendimiento metabólico de esta vía están determinados tanto por los mismos niveles glucosa así como por la actividad de la G6PD. Por esta vía, la glucosa regula la trascripción de varios genes lipogénicos. En algunos embriones hembra producidos in vitro, se registra un retardo en la normal inactivación de uno de sus cromosomas X, lo cual se traduce en una doble actividad de los genes allí ubicados, si se compara con los embriones macho producidos in vitro. Se postula entonces que, la sobre-regulación de la vía PF a consecuencia de la doble dosis de su enzima...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Compensación dosis cromosómica; Genes lipogénicos; Metabolismo glucosa; Chromosome dose compensation; Lipogenic genes; Glucose metabolism.
Ano: 2008 URL: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-548X2008000200006
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Glucose metabolism in rats submitted to skeletal muscle denervation BABT
Nunes,Wilton Marlindo Santana; Mello,Maria Alice Rostom de.
This study analyzed the local and systemic effects of immobilization by denervation of the skeletal muscle on glucose metabolism. The rats were submitted to section of the right paw sciatic nerve. A reduction was observed in glucose uptake by the isolated soleus muscle of the denervated paw after 3 and 7 days, but not after 28 days in relation to the control animals. There was no difference after 3 and 7 days in glucose uptake by the soleus muscle of the opposite intact paw in relation to the control. There was increased glucose uptake in the same paw 28 days after denervation. The rate of glucose removal in response to exogenous insulin after 28 days of denervation was significantly higher than in control animals and those observed after 3 and 7 days of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Denervation; Glucose metabolism; Skeletal muscle.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000500006
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Interregional correlations of glucose metabolism between the basal ganglia and different cortical areas: an ultra-high resolution PET/MRI fusion study using 18F-FDG BJMBR
Kim,J.H.; Son,Y.D.; Kim,J.M.; Kim,H.K.; Kim,Y.B.; Lee,C.; Oh,C.H..
Basal ganglia have complex functional connections with the cerebral cortex and are involved in motor control, executive functions of the forebrain, such as the planning of movement, and cognitive behaviors based on their connections. The aim of this study was to provide detailed functional correlation patterns between the basal ganglia and cerebral cortex by conducting an interregional correlation analysis of the 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) data based on precise structural information. Fifteen participants were scanned with 7-Tesla magnetic resonance imaging (MRI) and high resolution research tomography (HRRT)-PET fusion system using 18F-FDG. For detailed interregional correlation analysis, 24 subregions of the basal...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Basal ganglia; 18F-FDG PET/MRI; ROI-based interregional correlation analysis; Functional correlation; Glucose metabolism.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000100613
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Effect of protein malnutrition on the glycolytic and glutaminolytic enzyme activity of rat thymus and mesenteric lymph nodes BJMBR
The activity of important glycolytic enzymes (hexokinase, phosphofructokinase, aldolase, phosphohexoseisomerase, pyruvate kinase and lactate dehydrogenase) and glutaminolytic enzymes (phosphate-dependent glutaminase) was determined in the thymus and mesenteric lymph nodes of Wistar rats submitted to protein malnutrition (6% protein in the diet rather than 20%) from conception to 12 weeks after birth. The wet weight (g) of the thymus and mesenteric lymph nodes decreased due to protein malnutrition by 87% (from 0.30 ± 0.05 to 0.04 ± 0.01) and 75% (0.40 ± 0.04 to 0.10 ± 0.02), respectively. The protein content was reduced only in the thymus from 102.3 ± 4.4 (control rats) to 72.6 ± 6.6 (malnourished rats). The glycolytic enzymes were not affected by protein...
Palavras-chave: Protein malnutrition; Glucose metabolism; Glutamine metabolism; Thymus; Lymph nodes.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000600003
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A link between sleep loss, glucose metabolism and adipokines BJMBR
Padilha,H.G.; Crispim,C.A.; Zimberg,I.Z.; De-Souza,D.A.; Waterhouse,J.; Tufik,S.; de-Mello,M.T.
The present review evaluates the role of sleep and its alteration in triggering problems of glucose metabolism and the possible involvement of adipokines in this process. A reduction in the amount of time spent sleeping has become an endemic condition in modern society, and a search of the current literature has found important associations between sleep loss and alterations of nutritional and metabolic contexts. Studies suggest that sleep loss is associated with problems in glucose metabolism and a higher risk for the development of insulin resistance and type 2 diabetes mellitus. The mechanism involved may be associated with the decreased efficacy of regulation of the hypothalamus-pituitary-adrenal axis by negative feedback mechanisms in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Glucose metabolism; Insulin resistance; Sleep loss; Adipokines; Type 2 diabetes mellitus; Inflammatory status.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011001000003
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