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Sales-Campos,H.; Basso,P.J.; Alves,V.B.F.; Fonseca,M.T.C.; Bonfá,G.; Nardini,V.; Cardoso,C.R.B.. |
Crohn's disease (CD) and ulcerative colitis (UC) are intestinal disorders that comprise the inflammatory bowel diseases (IBD). These disorders have a significant effect on the quality of life of affected patients and the increasing number of IBD cases worldwide is a growing concern. Because of the overall burden of IBD and its multifactorial etiology, efforts have been made to improve the medical management of these inflammatory conditions. The classical therapeutic strategies aim to control the exacerbated host immune response with aminosalicylates, antibiotics, corticosteroids, thiopurines, methotrexate and anti-tumor necrosis factor (TNF) biological agents. Although successful in the treatment of several CD or UC conditions, these drugs have limited... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Inflammatory bowel disease; Crohn's disease; Ulcerative colitis; Treatment; Immune modulation; Cellular therapy. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000200096 |
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