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Xylitol inhibits J774A.1 macrophage adhesion in vitro BABT
Ferreira,Aline Siqueira; Souza,Maria Aparecida de; Raposo,Nádia Rezende Barbosa; Ferreira,Ana Paula; Silva,Silvio Silvério da.
The aim of this work was to evaluate the effect of xylitol on J774A.1 macrophage adhesion. Adhesion consisted of a three-hour interval, at room temperature, followed by washing and cell incubation at 37ºC/5% CO2/ 48h. Xylitol was used to treat the cells either before (for 24h) or after the cell incubation (for 48h) at 5% as final concentration in both the situations. It was found that xylitol was effective in preventing the adhesion in both the conditions in spite of the former being 100-fold greater and significant (p < 0.001). The results pointed to an important xylitol action on macrophage adhesion, which should be further investigated as an inflammatory control.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Adhesion; J774A; 1 macrophages; Xylitol.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000600017
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